Hepatincolaceae (Alphaproteobacteria) are Distinct From Holosporales and Independently Evolved to Associate With Ecdysozoa
Environmental Microbiology,
Год журнала:
2025,
Номер
27(1)
Опубликована: Янв. 1, 2025
ABSTRACT
The
Hepatincolaceae
(
Alphaproteobacteria
)
are
a
group
of
bacteria
that
inhabit
the
gut
arthropods
and
other
ecdysozoans,
associating
extracellularly
with
microvilli.
Previous
phylogenetic
studies,
primarily
single‐gene
analyses,
suggested
their
relationship
to
Holosporales
,
which
includes
intracellular
in
protist
hosts.
However,
genomics
is
still
its
early
stages.
In
this
study,
number
available
genomes
was
increased
examine
evolutionary
functional
characteristics.
It
found
previous
grouping
incorrect
due
sequence
compositional
biases
form
an
independent
branch
within
.
This
led
reinterpretation
features,
proposing
new
scenario
involves
adaptation
host
association
compared
distinct
specificities.
exhibit
greater
nutritional
flexibility,
utilising
various
molecules
thriving
anaerobic
conditions.
they
have
less
complex
mechanism
for
modulating
interactions,
likely
direct
than
those
bacteria.
addition,
representatives
show
several
lineage‐specific
traits
related
differences
species
life
Язык: Английский
Symbionts of predatory protists are widespread in the oceans and related to animal pathogens
Cell Host & Microbe,
Год журнала:
2025,
Номер
33(2), С. 182 - 199.e7
Опубликована: Фев. 1, 2025
Язык: Английский
An Evolutionary-Focused Review of the Holosporales (Alphaproteobacteria): Diversity, Host Interactions, and Taxonomic Re-ranking as Holosporineae Subord. Nov
Microbial Ecology,
Год журнала:
2025,
Номер
88(1)
Опубликована: Март 14, 2025
Abstract
The
order
Holosporales
is
a
broad
and
ancient
lineage
of
bacteria
obligatorily
associated
with
eukaryotic
hosts,
mostly
protists.
Significantly,
this
similar
to
other
evolutionary
distinct
bacterial
lineages
(e.g.
Rickettsiales
Chlamydiae
).
Here,
we
provide
detailed
comprehensive
account
on
the
current
knowledge
.
First,
acknowledging
up-to-date
phylogenetic
reconstructions
recent
nomenclatural
proposals,
reevaluate
their
taxonomy,
thus
re-ranking
them
as
suborder,
i.e.
Holosporineae
,
within
Rhodospirillales
Then,
examine
diversity
presenting
20
described
genera
many
yet
undescribed
sub-lineages,
well
variety
respective
environments
provenance
which
belong
several
different
supergroups.
Noteworthy
representatives
are
infectious
intranuclear
Holospora
host
manipulator
‘
Caedimonas
’,
farmed
shrimp
pathogen
Candidatus
Hepatobacter’.
Next,
put
these
in
context
whole
by
comparing
available
data
least
studied
representatives,
including
genome
sequences.
Accordingly,
reason
most
probable
trajectories
for
interactions,
specificity,
emergence
potential
pathogens
aquaculture
possibly
humans,
future
research
directions
investigate
those
open
points
Язык: Английский
Cellular interactions and evolutionary origins of endosymbiotic relationships with ciliates
The ISME Journal,
Год журнала:
2024,
Номер
18(1)
Опубликована: Янв. 1, 2024
Abstract
As
unicellular
predators,
ciliates
engage
in
close
associations
with
diverse
microbes,
laying
the
foundation
for
establishment
of
endosymbiosis.
Originally
heterotrophic,
demonstrate
ability
to
acquire
phototrophy
by
phagocytizing
algae
or
sequestering
algal
plastids.
This
adaptation
enables
them
gain
photosynthate
and
develop
resistance
unfavorable
environmental
conditions.
The
integration
acquired
intrinsic
phagotrophy
results
a
trophic
mode
known
as
mixotrophy.
Additionally,
can
harbor
thousands
bacteria
various
intracellular
regions,
including
cytoplasm
nucleus,
exhibiting
species
specificity.
Under
prolonged
specific
selective
pressure
within
hosts,
bacterial
endosymbionts
evolve
unique
lifestyles
undergo
particular
reductions
metabolic
activities.
Investigating
research
advancements
endosymbiotic
cases
will
contribute
elucidate
patterns
cellular
interaction
unravel
evolutionary
origins
complex
traits.
Язык: Английский
Addictive manipulation: a perspective on the role of reproductive parasitism in the evolution of bacteria–eukaryote symbioses
Biology Letters,
Год журнала:
2024,
Номер
20(9)
Опубликована: Сен. 1, 2024
Wolbachia
bacteria
encompass
noteworthy
reproductive
manipulators
of
their
arthropod
hosts.
which
influence
host
reproduction
to
favour
own
transmission,
also
exploiting
toxin–antitoxin
systems.
Recently,
multiple
other
bacterial
symbionts
arthropods
have
been
shown
display
comparable
manipulative
capabilities.
Here,
we
wonder
whether
such
phenomena
are
truly
restricted
We
focused
on
protists,
primary
models
for
evolutionary
investigations
eukaryotes
due
diversity
and
antiquity,
but
still
overall
under-investigated.
After
a
thorough
re-examination
the
literature
bacterial–protist
interactions
with
this
question
in
mind,
conclude
that
‘addictive
manipulators’
protists
do
exist,
probably
widespread,
overlooked
until
now
as
consequence
fact
commonly
host-centred,
thus
ineffective
detect
behaviour.
Additionally,
posit
systems
crucial
these
addictive
manipulation
result
recurrent
repurposing.
This
indicates
intriguing
functional
analogy
molecular
homology
plasmid–bacterial
interplays.
Finally,
remark
affiliated
specific
lineages
ancient
associations
diverse
eukaryotes.
suggests
possible
role
paving
way
evolution
associated
multicellular
organisms.
Язык: Английский
“Candidatus Intestinibacterium parameciiphilum”—member of the “Candidatus Paracaedibacteraceae” family (Alphaproteobacteria, Holosporales) inhabiting the ciliated protist Paramecium
International Microbiology,
Год журнала:
2023,
Номер
27(3), С. 659 - 671
Опубликована: Авг. 24, 2023
Abstract
Protists
frequently
host
diverse
bacterial
symbionts,
in
particular
those
affiliated
with
the
order
Holosporales
(
Alphaproteobacteria
).
All
characterised
members
of
this
lineage
have
been
retrieved
obligate
association
a
wide
range
eukaryotes,
especially
multiple
protist
lineages
(e.g.
amoebozoans,
ciliates,
cercozoans,
euglenids,
and
nucleariids),
as
well
some
metazoans
(especially
arthropods
related
ecdysozoans).
While
genus
Paramecium
other
ciliates
deeply
investigated
for
presence
known
family
“
Candidatus
Paracaedibacteraceae”
)
are
currently
underrepresented
such
hosts.
Herein,
we
report
description
Intestinibacterium
parameciiphilum”
within
Paracaedibacteraceae”,
inhabiting
cytoplasm
biaurelia
.
This
novel
bacterium
is
almost
twice
big
its
relative
nucleariae”
from
opisthokont
Nuclearia
does
not
present
surrounding
halo.
Based
on
phylogenetic
analyses
16S
rRNA
gene
sequences,
identified
six
further
potential
species-level
genus.
provenance
respective
samples,
environmental
distribution
representatives
Intestinibacterium”
species.
Obtained
results
consistent
an
endosymbiotic
lifestyle,
protists,
freshwater
ones,
Thus,
available
data
suggest
that
protists
could
be
ancestral
condition
Язык: Английский