Ultrasound-responsive Microfibers Promoted Infected Wound Healing with Neuro-vascularization by Segmented Sonodynamic Therapy and Electrical Stimulation

Biomaterials, Год журнала: 2024, Номер 313, С. 122803 - 122803

Опубликована: Сен. 2, 2024

Язык: Английский

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Hierarchical Interconnected Porous Scaffolds with Regulated Interfacial Nanotopography Exhibit Antimicrobial, Alleviate Inflammation, Neovascularization, and Tissue Integration for Bone Regeneration

Biomaterials, Год журнала: 2025, Номер 318, С. 123186 - 123186

Опубликована: Фев. 13, 2025

Язык: Английский

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Impact of scandium on the microstructure, mechanical properties, corrosion behaviors and in-vitro biocompatibility of a Zn-0.1Li alloy

Journal of Material Science and Technology, Год журнала: 2025, Номер 229, С. 235 - 251

Опубликована: Фев. 18, 2025

Язык: Английский

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Geometric design and mechanical performance of isotropic bone scaffolds

Materials & Design, Год журнала: 2025, Номер unknown, С. 113829 - 113829

Опубликована: Март 1, 2025

Язык: Английский

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Magnesium-induced strengthening, degradation and osteogenesis for additively manufactured Zn-Mg orthopedic implants

Acta Biomaterialia, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

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The effect of copper content in Ti-Cu alloy with bone regeneration ability on the phenotypic transformation of macrophages

Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер unknown, С. 114641 - 114641

Опубликована: Март 1, 2025

Язык: Английский

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The critical role of surface characteristics in 3D-printed biodegradable Zn-based porous scaffolds for bone defect repair

Virtual and Physical Prototyping, Год журнала: 2025, Номер 20(1)

Опубликована: Март 24, 2025

Язык: Английский

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Research advances and future perspectives of zinc-based biomaterials for additive manufacturing

Rare Metals, Год журнала: 2025, Номер unknown

Опубликована: Март 25, 2025

Язык: Английский

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Ultrasound‐Driven Innervated Bone Regeneration in Additively Manufactured Degradable Metallic Scaffolds

Advanced Healthcare Materials, Год журнала: 2025, Номер unknown

Опубликована: Март 28, 2025

Abstract Bone tissues are densely innervated by nerve fibers throughout the periosteum and mineralized bone. The impairment of bone regeneration is a critical factor contributing to challenges in osteoporotic remodeling repair. Herein, an “ultrasound‐driven regeneration” strategy proposed additively manufactured degradable Zn‐Cu scaffolds. vitro investigations with RSC96 cells elucidated synergistic promotion low‐intensity pulsed ultrasound (LIPUS) metal cations on Schwann cell proliferation exosome secretion. Notably, these cell‐derived exosomes, once internalized neighboring marrow stromal (BMSCs), significantly enhanced their migration, osteogenic differentiation, extracellular matrix deposition, indicating potent mechanism for regeneration. Furthermore, vivo evaluation validated that LIPUS stimulation activated S100β‐positive facilitated peripheral within cranial defects, leading accelerated healing rats implantation over 2‐ 6‐week recovery periods. This work provides focusing activation enhancement paracrine effect, especially secretion, which further recruited surrounding BMSCs promoted differentiation. study holds considerable promise clinical applications translation treatment defects.

Язык: Английский

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Bioactive Zn ingredients endow Ti-Zn composites with exceptional mechanical and osteogenic properties as biomedical implants

Biomaterials Advances, Год журнала: 2025, Номер unknown, С. 214308 - 214308

Опубликована: Апрель 1, 2025

Язык: Английский

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