Genome-Wide Association Study Reveals Novel Loci and Candidate Genes for Birth Weight in Pigs DOI Creative Commons
Jiajia Liu, Yué Zeng, Yu Tian

и другие.

Animals, Год журнала: 2025, Номер 15(6), С. 825 - 825

Опубликована: Март 13, 2025

Birth weight is a key economic trait in pig breeding, affecting pre-weaning survival, growth performance, and overall production efficiency. However, the genetic factors underlying birth remain incompletely understood. This study aimed to identify variants associated with pigs through genome-wide association (GWAS) using 50K SNP genotyping data from 1125 Landrace pigs. Seven significant SNPs linked were identified, along 13 potential candidate genes. To validate these findings, population was expanded include 998 Yorkshire pigs, totaling 2123 individuals. Validation identified two novel on chromosomes 1 16, as well previously unreported gene MARCHF11, which weight. These findings enhance understanding of architecture provide targets for molecular marker-assisted selection (MAS). The results offer valuable insights into breeding strategies at improving piglet survival rates underscores utility GWAS identifying loci economically important traits livestock populations.

Язык: Английский

Genome-Wide Association Study Reveals Novel Loci and Candidate Genes for Birth Weight in Pigs DOI Creative Commons
Jiajia Liu, Yué Zeng, Yu Tian

и другие.

Animals, Год журнала: 2025, Номер 15(6), С. 825 - 825

Опубликована: Март 13, 2025

Birth weight is a key economic trait in pig breeding, affecting pre-weaning survival, growth performance, and overall production efficiency. However, the genetic factors underlying birth remain incompletely understood. This study aimed to identify variants associated with pigs through genome-wide association (GWAS) using 50K SNP genotyping data from 1125 Landrace pigs. Seven significant SNPs linked were identified, along 13 potential candidate genes. To validate these findings, population was expanded include 998 Yorkshire pigs, totaling 2123 individuals. Validation identified two novel on chromosomes 1 16, as well previously unreported gene MARCHF11, which weight. These findings enhance understanding of architecture provide targets for molecular marker-assisted selection (MAS). The results offer valuable insights into breeding strategies at improving piglet survival rates underscores utility GWAS identifying loci economically important traits livestock populations.

Язык: Английский

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