International Journal of Nanomedicine,
Год журнала:
2024,
Номер
Volume 19, С. 12719 - 12742
Опубликована: Ноя. 1, 2024
Hydrogels
can
be
rationally
designed
as
multifunctional
platforms
with
structures
and
functions
for
various
biomedical
applications.
Because
of
their
excellent
biochemical
mechanical
properties,
hydrogels
have
shown
great
potential
promoting
angiogenesis,
an
increasing
amount
research
has
been
devoted
to
designing
developing
new
hydrogels.
However,
a
systematic
detailed
review
that
promote
angiogenesis
is
lacking.
This
paper
comprehensively
summarizes
the
design
strategies
different
kinds
functional
anti-oxidant,
substance-delivery,
stimulus-responsive,
self-healing,
conductive,
wound-monitoring
properties.
The
applications
in
wound
healing,
bone
regeneration,
treatment
myocardial
ischemia
are
discussed.
Finally,
future
development
directions
proposed
along
related
diseases.
The
rise
of
antibiotic
resistance
poses
a
critical
threat
to
global
health,
necessitating
the
development
novel
antibacterial
strategies
mitigate
this
growing
challenge.
Biomimetic
materials,
inspired
by
natural
biological
systems,
have
emerged
as
promising
solution
in
context.
These
mimicking
entities
such
plants,
animals,
cells,
viruses,
and
enzymes,
offer
innovative
approaches
combat
bacterial
infections
effectively.
This
review
delves
into
integration
biomimicry
with
materials
science
develop
agents
that
are
not
only
effective
but
also
biocompatible
less
likely
induce
resistance.
study
explores
design
function
various
biomimetic
highlighting
their
therapeutic
potential
anti-infection
applications.
Further,
provides
comprehensive
summary
recent
advancements
field,
illustrating
how
these
been
engineered
enhance
efficacy
safety.
discusses
challenges
facing
transition
from
laboratory
clinical
settings,
scalability,
cost-effectiveness,
long-term
stability.
Lastly,
vast
opportunities
hold
for
future
therapy,
suggesting
continued
research
multidisciplinary
collaboration
will
be
essential
realize
full
potential.
International Journal of Nanomedicine,
Год журнала:
2024,
Номер
Volume 19, С. 12719 - 12742
Опубликована: Ноя. 1, 2024
Hydrogels
can
be
rationally
designed
as
multifunctional
platforms
with
structures
and
functions
for
various
biomedical
applications.
Because
of
their
excellent
biochemical
mechanical
properties,
hydrogels
have
shown
great
potential
promoting
angiogenesis,
an
increasing
amount
research
has
been
devoted
to
designing
developing
new
hydrogels.
However,
a
systematic
detailed
review
that
promote
angiogenesis
is
lacking.
This
paper
comprehensively
summarizes
the
design
strategies
different
kinds
functional
anti-oxidant,
substance-delivery,
stimulus-responsive,
self-healing,
conductive,
wound-monitoring
properties.
The
applications
in
wound
healing,
bone
regeneration,
treatment
myocardial
ischemia
are
discussed.
Finally,
future
development
directions
proposed
along
related
diseases.
