American Journal of Cancer Research,
Год журнала:
2024,
Номер
14(9), С. 4580 - 4596
Опубликована: Янв. 1, 2024
The
treatment
for
liver
cancer
has
transitioned
from
traditional
surgical
resection
to
interventional
therapies,
which
have
become
increasingly
popular
among
patients
due
their
minimally
invasive
nature
and
significant
local
efficacy.
However,
with
advancements
in
technologies,
accurately
assessing
patient
response
predicting
long-term
survival
a
crucial
research
topic.
Over
the
past
decade,
machine
algorithms
made
remarkable
progress
medical
field,
particularly
hepatology
prognosis
studies
of
hepatocellular
carcinoma
(HCC).
Machine
algorithms,
including
deep
learning
learning,
can
identify
prognostic
patterns
trends
by
analyzing
vast
amounts
clinical
data.
Despite
advancements,
several
issues
remain
unresolved
prediction
using
algorithms.
Key
challenges
main
controversies
include
effectively
integrating
multi-source
data
improve
accuracy,
addressing
privacy
ethical
concerns,
enhancing
transparency
interpretability
algorithm
decision-making
processes.
This
paper
aims
systematically
review
analyze
current
applications
potential
undergoing
therapy
cancer,
providing
theoretical
empirical
support
future
practice.
The Lancet Regional Health - Europe,
Год журнала:
2025,
Номер
50, С. 101171 - 101171
Опубликована: Фев. 19, 2025
Biliary
tract
cancer
(BTC)
is
becoming
more
common
worldwide,
with
geographic
differences
in
incidence
and
risk
factors.
In
Europe,
BTC
may
be
associated
primary
sclerosing
cholangitis,
lithiasis,
liver
cirrhosis,
but
frequently
observed
as
a
sporadic
disease.
increasingly
affects
patients
under
60
years,
resulting
significant
social
economic
burden.
Early
diagnosis
remains
challenging
due
to
vague
symptoms
50%
of
BTC,
lack
specific
biomarkers,
late
presentation
poor
prognosis.
The
identification
at
increased
reliable
biomarkers
require
collaborative
efforts
make
faster
progress.
This
Series
paper
highlights
the
disparities
access
diagnostic
tools
multidisciplinary
care
particularly
economically
disadvantaged
regions,
while
identifying
priority
areas
for
improvement.
Addressing
these
inequities
requires
harmonised
guidelines,
accelerated
pathways
curative
treatments,
improved
awareness
among
healthcare
professionals
public.
Multidisciplinary
teams
(MDTs)
are
crucial
improving
patient
outcomes,
yet
inconsistencies
exist
their
implementation
not
only
between
different
countries,
also
centres
within
country.
Collaboration
standardisation
treatment
protocols
across
Europe
essential
effectively
address
management
BTC.
Biomedicines,
Год журнала:
2024,
Номер
12(7), С. 1624 - 1624
Опубликована: Июль 22, 2024
Hepatocellular
carcinoma
(HCC),
the
predominant
primary
liver
tumor,
remains
one
of
most
lethal
cancers
worldwide,
despite
advances
in
therapy
recent
years.
In
addition
to
traditional
chemically
and
dietary-induced
HCC
models,
a
broad
spectrum
novel
preclinical
tools
have
been
generated
following
advent
transgenic,
transposon,
organoid,
silico
technologies
overcome
this
gloomy
scenario.
These
models
become
rapidly
robust
instruments
unravel
molecular
pathogenesis
cancer
establish
new
therapeutic
approaches
against
deadly
disease.
The
present
review
article
aims
summarize
discuss
commonly
used
for
HCC,
evaluating
their
strengths
weaknesses.
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Ноя. 15, 2024
Incidence
of
liver
cancer
as
one
the
most
common
cancers
worldwide
and
become
significant
contributor
for
mortality
among
patients.
The
disease
burden,
risk
factors,
trends
in
incidence
globally
was
described
subsequently
estimated
projections
or
by
2040.
Data
regarding
age-standardized
rates
obtained
from
multiple
databases,
including
GLOBOCAN
2020,
CI5
volumes
I–XI,
WHO
database,
Global
Burden
Disease
(GBD)-2019.
Concentrating
on
variations,
this
thorough
analysis
offers
insights
into
patterns
based
gender
age.
Our
findings
encompass
indicators,
(ASRs),
average
annual
percentage
change
(AAPC),
future
extending
up
to
year
Liver
holds
sixth
position
terms
frequently
diagnosed
stands
leading
cause
cancer-related
deaths
accounting
905,677
new
cases
782,000
fatalities.
Additionally,
contributed
12,528,421
disability-adjusted
life
years
(DALYs),
with
an
DALYs
rate
161.92
2019
worldwide.
age-specific
exhibited
variations
across
different
regions,
showing
a
fivefold
difference
males
females.
A
increase
observed
North
Europe
Asia,
while
African
countries
reported
higher
burden
(ASR,
10
per
100,000)
compared
developed
countries.
Since
last
few
years,
have
increased
attained
Annual
Average
Percentage
Change
(AAPC)
7.7
(95%
CI
3.9–11.6)
men
highest
AAPC
12.2
9.5–15.0)
women.
In
2019,
Western
emerged
high-risk
region
related
smoking
alcohol
consumption,
high-income
America
carried
high
associated
body-mass
index.
projected
trend
indicates
surge
incident
cases,
expected
rise
around
905,347
1,392,474
This
study
evidence
pertinent
cancer,
particularly
both
young
older
adults,
encompassing
females,
well
those
who
are
HIV-infected
HBsAg
positive.
population
poses
public
health
concern
that
warrants
attention
healthcare
professionals
prioritize
promotion
awareness
development
effective
prevention
strategies,
many
developing
Tomography,
Год журнала:
2024,
Номер
10(11), С. 1814 - 1831
Опубликована: Ноя. 18, 2024
Advancements
in
artificial
intelligence
(AI)
have
significantly
transformed
the
field
of
abdominal
radiology,
leading
to
an
improvement
diagnostic
and
disease
management
capabilities.
This
narrative
review
seeks
evaluate
current
standing
AI
imaging,
with
a
focus
on
recent
literature
contributions.
work
explores
diagnosis
characterization
hepatobiliary,
pancreatic,
gastric,
colonic,
other
pathologies.
In
addition,
role
has
been
observed
help
differentiate
renal,
adrenal,
splenic
disorders.
Furthermore,
workflow
optimization
strategies
quantitative
imaging
techniques
used
for
measurement
tissue
properties,
including
radiomics
deep
learning,
are
highlighted.
An
assessment
how
these
advancements
enable
more
precise
diagnosis,
tumor
description,
body
composition
evaluation
is
presented,
which
ultimately
advances
clinical
effectiveness
productivity
radiology.
Despite
technical,
ethical,
legal
challenges
persist,
challenges,
as
well
opportunities
future
development,
Bioengineering,
Год журнала:
2024,
Номер
11(12), С. 1243 - 1243
Опубликована: Дек. 9, 2024
Liver
disease
can
significantly
impact
life
expectancy,
making
early
diagnosis
and
therapeutic
intervention
critical
challenges
in
medical
care.
Imaging
diagnostics
play
a
crucial
role
diagnosing
managing
liver
diseases.
Recently,
the
application
of
artificial
intelligence
(AI)
imaging
analysis
has
become
indispensable
healthcare.
AI,
trained
on
vast
datasets
images,
sometimes
demonstrated
diagnostic
accuracy
that
surpasses
human
experts.
AI-assisted
are
expected
to
contribute
standardization
quality.
Furthermore,
AI
potential
identify
image
features
imperceptible
humans,
thereby
playing
an
essential
clinical
decision-making.
This
capability
enables
physicians
make
more
accurate
diagnoses
develop
effective
treatment
strategies,
ultimately
improving
patient
outcomes.
Additionally,
is
anticipated
powerful
tool
personalized
medicine.
By
integrating
individual
data
with
information,
propose
optimal
plans
for
treatment,
it
component
provision
most
appropriate
care
each
patient.
Current
reports
highlight
advantages
As
technology
continues
evolve,
advance
treatments
overall
improvements
healthcare
Annals of Medicine and Surgery,
Год журнала:
2025,
Номер
87(4), С. 2180 - 2186
Опубликована: Фев. 27, 2025
The
application
of
artificial
intelligence
(AI)
technology
in
the
medical
field,
particularly
surgical
operations,
has
evolved
from
science
fiction
to
a
crucial
tool.
With
continuous
advancements
computational
power
and
algorithmic
technology,
AI
is
reshaping
medicine
landscape.
From
preoperative
diagnosis
planning
intraoperative
real-time
navigation
assistance
postoperative
rehabilitation
follow-up
management,
significantly
enhanced
precision
safety
procedures.
This
paper
systematically
reviews
development
current
applications
surgery,
focusing
on
specific
case
studies
procedures,
diagnostic
assistance,
navigation,
highlighting
its
significant
contributions
improving
safety.
Despite
obvious
advantages
success,
reducing
complications,
accelerating
patient
recovery,
use
surgery
still
faces
numerous
challenges,
including
cost-effectiveness,
dependency,
data
privacy
security,
clinical
integration,
physician
training.
review
summarizes
medicine,
highlights
benefits
limitations,
discusses
challenges
future
directions
integrating
into
practice.
Biomedicines,
Год журнала:
2025,
Номер
13(5), С. 1244 - 1244
Опубликована: Май 20, 2025
Hepatocellular
carcinoma
remains
one
of
the
leading
contributors
to
global
cancer
mortality,
frequently
stemming
from
chronic
liver
conditions,
such
as
viral
hepatitis,
non-alcoholic
fatty
disease,
and
alcohol-induced
cirrhosis.
While
antiviral
treatments
have
made
significant
strides,
rising
prevalence
hepatocellular
linked
non-infectious
causes
underscores
pressing
demand
for
more
effective
diagnostic
tools
therapeutic
interventions.
Advances
in
imaging
liquid
biopsy
technologies
facilitated
early
detection
diagnosis,
treatment
strategies
are
diversifying
include
immune
checkpoint
inhibitors,
tyrosine
kinase
interventional
therapies.
Translational
therapies
advanced
improved
surgical
opportunities
patient
survival.
Artificial
intelligence
has
played
a
transformative
role
diagnosis
carcinoma,
terms
image
analysis,
histopathologic
classification,
drug
development,
targeted
therapy.
The
future
lies
precision
oncology
collaboration
multidisciplinary
teams,
well
detection.
ultimate
goal
is
keep
patients
alive
longer
reduce
burden
this
complex
malignancy.
