Neuronal mechanisms underlying opioid-induced respiratory depression: our current understanding DOI
Jan‐Marino Ramirez, Nicholas Burgraff, Aguan Wei

и другие.

Journal of Neurophysiology, Год журнала: 2021, Номер 125(5), С. 1899 - 1919

Опубликована: Апрель 7, 2021

Opioid-induced respiratory depression (OIRD) represents the primary cause of death associated with therapeutic and recreational opioid use. Within United States, rate from abuse since early 1990s has grown disproportionally, prompting classification as a nationwide “epidemic.” Since this time, we have begun to unravel many fundamental cellular systems-level mechanisms opioid-related death. However, factors such individual vulnerability, neuromodulatory compensation, redundancy effects across central peripheral nervous systems created barrier concise, integrative view OIRD. review, bring together multiple perspectives in field OIRD create an overarching viewpoint what know, where essential topic research going forward into future.

Язык: Английский

Swaying gel: chemo-mechanical self-oscillation based on dynamic buckling DOI Creative Commons
Mutian Hua, Cheolgyu Kim, Yingjie Du

и другие.

Matter, Год журнала: 2021, Номер 4(3), С. 1029 - 1041

Опубликована: Янв. 28, 2021

Язык: Английский

Процитировано

87
Emergent Elements of Inspiratory Rhythmogenesis: Network Synchronization and Synchrony Propagation DOI Creative Commons
Sufyan Ashhad, Jack L. Feldman

Neuron, Год журнала: 2020, Номер 106(3), С. 482 - 497.e4

Опубликована: Март 3, 2020

Язык: Английский

Процитировано

86
Synchronized Cardiac Impulses Emerge From Heterogeneous Local Calcium Signals Within and Among Cells of Pacemaker Tissue DOI Creative Commons

Rostislav Bychkov,

Magdalena Juhaszova, Kenta Tsutsui

и другие.

JACC. Clinical electrophysiology, Год журнала: 2020, Номер 6(8), С. 907 - 931

Опубликована: Авг. 1, 2020

Язык: Английский

Процитировано

84
Divergent brainstem opioidergic pathways that coordinate breathing with pain and emotions DOI Creative Commons
Shijia Liu, Mao Ye, Gerald M. Pao

и другие.

Neuron, Год журнала: 2021, Номер 110(5), С. 857 - 873.e9

Опубликована: Дек. 17, 2021

Язык: Английский

Процитировано

84
Neuronal mechanisms underlying opioid-induced respiratory depression: our current understanding DOI
Jan‐Marino Ramirez, Nicholas Burgraff, Aguan Wei

и другие.

Journal of Neurophysiology, Год журнала: 2021, Номер 125(5), С. 1899 - 1919

Опубликована: Апрель 7, 2021

Opioid-induced respiratory depression (OIRD) represents the primary cause of death associated with therapeutic and recreational opioid use. Within United States, rate from abuse since early 1990s has grown disproportionally, prompting classification as a nationwide “epidemic.” Since this time, we have begun to unravel many fundamental cellular systems-level mechanisms opioid-related death. However, factors such individual vulnerability, neuromodulatory compensation, redundancy effects across central peripheral nervous systems created barrier concise, integrative view OIRD. review, bring together multiple perspectives in field OIRD create an overarching viewpoint what know, where essential topic research going forward into future.

Язык: Английский

Процитировано

76