Insights into Hierarchical Structure–Property–Application Relationships of Advanced Bacterial Cellulose Materials DOI
Zhuotong Wu, Shiyan Chen,

Jing Li

и другие.

Advanced Functional Materials, Год журнала: 2023, Номер 33(12)

Опубликована: Янв. 19, 2023

Abstract Bacterial cellulose (BC) is an environmentally friendly biomaterial that widely investigated because it possesses a unique hierarchical nanofiber network structure as well extraordinary performance. In this review, the formation of BC from perspective biosynthesis illustrated based on its basic chemical and crystal structure. Moreover, design processing BC‐based advanced materials through biosynthesis, physical, and/or modification are also reviewed. The intrinsic characteristics BC, derived structure, analyzed to understand structure–property–application relationships. applications reviewed, such high‐strength structural utilizing properties nanofibers, energy conversion storage, bioelectronic interfaces, environmental remediation, thermal management ion transport 3D structures these materials. addition, authors offer their opinions potential future research directions for sustainably developing

Язык: Английский

Recent advances in neurotechnologies with broad potential for neuroscience research DOI
Abraham Vázquez‐Guardado, Yiyuan Yang, Amay J. Bandodkar

и другие.

Nature Neuroscience, Год журнала: 2020, Номер 23(12), С. 1522 - 1536

Опубликована: Ноя. 16, 2020

Язык: Английский

Процитировано

169

Tether-free photothermal deep-brain stimulation in freely behaving mice via wide-field illumination in the near-infrared-II window DOI
Xiang Wu, Yuyan Jiang, Nicholas J. Rommelfanger

и другие.

Nature Biomedical Engineering, Год журнала: 2022, Номер 6(6), С. 754 - 770

Опубликована: Март 21, 2022

Язык: Английский

Процитировано

167

Electronic neural interfaces DOI
Milin Zhang, Zijian Tang, Xilin Liu

и другие.

Nature Electronics, Год журнала: 2020, Номер 3(4), С. 191 - 200

Опубликована: Апрель 13, 2020

Язык: Английский

Процитировано

161

Sono-optogenetics facilitated by a circulation-delivered rechargeable light source for minimally invasive optogenetics DOI Creative Commons
Xiang Wu, Xingjun Zhu, P. Andrew Chong

и другие.

Proceedings of the National Academy of Sciences, Год журнала: 2019, Номер 116(52), С. 26332 - 26342

Опубликована: Дек. 6, 2019

Optogenetics, which uses visible light to control the cells genetically modified with light-gated ion channels, is a powerful tool for precise deconstruction of neural circuitry neuron-subtype specificity. However, due limited tissue penetration light, invasive craniotomy and intracranial implantation tethered optical fibers are usually required in vivo optogenetic modulation. Here we report mechanoluminescent nanoparticles that can act as local sources brain when triggered by brain-penetrant focused ultrasound (FUS) through intact scalp skull. Mechanoluminescent be delivered into blood circulation via i.v. injection, recharged 400-nm photoexcitation superficial vessels during circulation, turned on FUS emit 470-nm repetitively stimulation. Unlike conventional "outside-in" approaches optogenetics fiber implantation, our method provides an "inside-out" approach deliver nanoscopic emitters intrinsic circulatory system switch them off at any time location interest without extravasation minimally interface.

Язык: Английский

Процитировано

158

The Locus Coeruleus- Norepinephrine System in Stress and Arousal: Unraveling Historical, Current, and Future Perspectives DOI Creative Commons
Jennifer A. Ross, Elisabeth J. Van Bockstaele

Frontiers in Psychiatry, Год журнала: 2021, Номер 11

Опубликована: Янв. 27, 2021

Arousal may be understood on a spectrum, with excessive sleepiness, cognitive dysfunction, and inattention one side, wakeful state in the middle, hypervigilance, panic, psychosis other side. However, historically, concepts of arousal stress have been challenging to define as measurable experimental variables. Divergent efforts study these subjects given rise several disciplines, including neurobiology, neuroendocrinology, neuroscience. We discuss technological advancements that chronologically led our current understanding system, focusing multifaceted nucleus locus coeruleus. share contemporary perspective hypotheses others context capabilities future developments will required move forward this area research.

Язык: Английский

Процитировано

144

Neural signal analysis with memristor arrays towards high-efficiency brain–machine interfaces DOI Creative Commons
Zhengwu Liu, Jianshi Tang, Bin Gao

и другие.

Nature Communications, Год журнала: 2020, Номер 11(1)

Опубликована: Авг. 25, 2020

Abstract Brain-machine interfaces are promising tools to restore lost motor functions and probe brain functional mechanisms. As the number of recording electrodes has been exponentially rising, signal processing capability brain–machine is falling behind. One key bottlenecks that they adopt conventional von Neumann architecture with digital computation fundamentally different from working principle human brain. In this work, we present a memristor-based neural analysis system, where bio-plausible characteristics memristors utilized analyze signals in analog domain high efficiency. proof-of-concept demonstration, memristor arrays used implement filtering identification epilepsy-related signals, achieving accuracy 93.46%. Remarkably, our system shows nearly 400× improvements power efficiency compared state-of-the-art complementary metal-oxide-semiconductor systems. This work demonstrates feasibility using for high-performance next-generation interfaces.

Язык: Английский

Процитировано

140

Organic Electrochemical Transistors for In Vivo Bioelectronics DOI
Ali Nawaz, Qian Liu, Wei Lin Leong

и другие.

Advanced Materials, Год журнала: 2021, Номер 33(49)

Опубликована: Окт. 4, 2021

Organic electrochemical transistors (OECTs) are presently a focus of intense research and hold great potential in expanding the horizons bioelectronics industry. The notable characteristics OECTs, including their electrolyte-gating, which offers intimate interfacing with biological environments, aqueous stability, make them particularly suitable to be operated within living organism (in vivo). Unlike existing vivo bioelectronic devices, mostly based on rigid metal electrodes, OECTs form soft mechanical contact milieu ensure high signal-to-noise ratio because powerful amplification capability. Such features desirable for wide range applications, electrophysiological recordings, neuron stimulation, neurotransmitter detection, regulation plant processes vivo. In this review, systematic compilation applications is presented that addressed by OECT technology. First, operating mechanisms, device design materials principles examined, then multiple examples provided from literature while identifying unique properties enable application progress. Finally, one critically looks at future technology applications.

Язык: Английский

Процитировано

136

Bioadhesive and conductive hydrogel-integrated brain-machine interfaces for conformal and immune-evasive contact with brain tissue DOI Creative Commons
Xiao Wang, Xiaotong Sun, Donglin Gan

и другие.

Matter, Год журнала: 2022, Номер 5(4), С. 1204 - 1223

Опубликована: Янв. 31, 2022

Язык: Английский

Процитировано

117

Synergistic piezoelectricity enhanced BaTiO3/polyacrylonitrile elastomer-based highly sensitive pressure sensor for intelligent sensing and posture recognition applications DOI
Junbin Yu, Shuai Xian,

Zhenpeng Zhang

и другие.

Nano Research, Год журнала: 2022, Номер 16(4), С. 5490 - 5502

Опубликована: Ноя. 9, 2022

Язык: Английский

Процитировано

117

Stretchable Mesh Nanoelectronics for 3D Single‐Cell Chronic Electrophysiology from Developing Brain Organoids DOI
Paul Le Floch, Qiang Li, Zuwan Lin

и другие.

Advanced Materials, Год журнала: 2022, Номер 34(11)

Опубликована: Янв. 11, 2022

Human induced pluripotent stem cell derived brain organoids have shown great potential for studies of human development and neurological disorders. However, quantifying the evolution electrical properties during is currently limited by measurement techniques, which cannot provide long-term stable 3D bioelectrical interfaces with developing organoids. Here, a cyborg organoid platform reported, in "tissue-like" stretchable mesh nanoelectronics are designed to match mechanical be folded organogenetic process progenitor or cells, distributing electrode arrays across The tissue-wide integrated show no interruption development, adapt volume morphological changes organogenesis, contacts neurons within development. seamless noninvasive coupling electrodes enables stable, continuous recording captures emergence single-cell action potentials from early-stage

Язык: Английский

Процитировано

97