Building towards an adolescent neural urbanome: Expanding environmental measures using linked external data (LED) in the ABCD study

Developmental Cognitive Neuroscience, Год журнала: 2024, Номер 65, С. 101338 - 101338

Опубликована: Янв. 4, 2024

Many recent studies have demonstrated that environmental contexts, both social and physical, an important impact on child adolescent neural behavioral development. The adoption of geospatial methods, such as in the Adolescent Brain Cognitive Development (ABCD) Study, has facilitated exploration many contexts surrounding participants' residential locations without creating additional burdens for research participants (i.e., youth families) neuroscience studies. However, number linked databases increases, developing a framework considers various domains related to environments external their home becomes crucial. Such needs identify structural contextual factors may yield inequalities children's built natural environments; these differences may, turn, result downstream negative effects children from historically minoritized groups. In this paper, we develop – which describe "adolescent urbanome" use it categorize newly geocoded information incorporated into ABCD Study by Linked External Data (LED) Environment & Policy Working Group. We also highlight relationships between measures possible applications Neural Urbanome. Finally, provide recommendations considerations regarding responsible communication data, highlighting potential harm groups through misuse.

Язык: Английский

---

Modality-Level Obstacles and Initiatives to Improve Representation in Fetal, Infant, and Toddler Neuroimaging Research Samples

Developmental Cognitive Neuroscience, Год журнала: 2025, Номер 72, С. 101505 - 101505

Опубликована: Янв. 5, 2025

Fetal, infant, and toddler (FIT) neuroimaging researchers study early brain development to gain insights into neurodevelopmental processes identify markers of neurobiological vulnerabilities target for intervention. However, the field has historically excluded people from global majority countries marginalized communities in FIT research. Inclusive representative samples are essential generalizing findings across modalities, such as magnetic resonance imaging, magnetoencephalography, electroencephalography, functional near-infrared spectroscopy, cranial ultrasonography. These techniques pose unique overlapping challenges equitable representation research through sampling bias, technical constraints, limited accessibility, insufficient resources. The present article adds conversation around need improve inclusivity by highlighting modality-specific historical current obstacles ongoing initiatives. We conclude discussing tangible solutions that transcend individual ultimately providing recommendations promote neuroscience.

Язык: Английский

---

Structural Determinants of School Discipline: Examining State-Level Racial Bias and Neighborhood Opportunity

Journal of the American Academy of Child & Adolescent Psychiatry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

---

Bioethical and Critical Consciousness in Clinical Translational Neuroscience

Journal of Clinical and Translational Science, Год журнала: 2025, Номер unknown, С. 1 - 27

Опубликована: Янв. 22, 2025

Clinical translational neuroscience (CTN) is positioned to generate novel discoveries for advancing treatments mental health disorders, but it held back today by the siloing of bioethical considerations from critical consciousness. In this article, we suggest that and consciousness can be paired intersect with structures power within which science clinical practice are conducted. We examine barriers adoption findings in perspective, especially context current collective attention widespread disparities access outcomes services, lack representation marginalized populations relevant sectors workforce, importance knowledge draws upon multicultural perspectives. provide 10 actionable solutions confront these CTN research, as informed existing frameworks such structural competency, adaptive calibration models, community-based participatory research. By integrating considerations, believe practitioners will better benefit cutting-edge research biological social sciences than past, alert biases equipped mitigate them, poised shepherd a robust generation future therapies practitioners.

Язык: Английский

---

Racial and ethnic socioenvironmental inequity and neuroimaging in psychiatry: a brief review of the past and recommendations for the future

Neuropsychopharmacology, Год журнала: 2024, Номер 50(1), С. 3 - 15

Опубликована: Июнь 20, 2024

Язык: Английский

---

Diversity and Representation in Developmental EEG: Participant Recruitment and Reporting

Опубликована: Янв. 1, 2025

Electroencephalography (EEG) is one of the main neuroscientific measures used with infants and children to identify potential biomarkers cognitive social developmental processes. Given implications EEG research within policy, clinical, educational domains, it important ensure that reported results are generalizable reproducible. In this review, provide an initial assessment previous current practices regarding participant recruitment demographic reporting, we carried out a systematic review six journals publishing most pediatric studies between 2011-2023. We identified 700 articles reporting on (N > 80,000). find did not complete basic information (e.g., race, ethnicity, socioeconomic status, geographical location). This trend persisted across years publication, suggesting continued underreporting. However, demographics differed journals, solutions for improving practices. Our also indicated samples consisted mostly White participants (78%) from North America Western Europe (85%). Moreover, median total sample size was 51 participants. discussion emphasizes need larger, more diverse greater transparency in studies, while providing recommendations address barriers representation.

Язык: Английский

---

Multimodal Measurement of Pubertal Development: Stage, Timing, Tempo, and Hormones

Child Development, Год журнала: 2025, Номер unknown

Опубликована: Янв. 7, 2025

ABSTRACT Using data from the Human Connectome Project in Development ( N = 1304; ages 5–21 years; 50% male; 59% White, 17% Hispanic, 13% Black, 9% Asian), multiple measures (self‐report, salivary hormones) and research designs (longitudinal, cross‐sectional) were used to characterize age‐related changes sex differences pubertal development. Both sexes exhibit a sigmoid trajectory of development; females show earlier timing increased tempo ~9–13 years, while males greater ~14–18 years. All hormones with age, testosterone DHEA levels rates change. Higher corresponded both sexes. These findings typical hormonal development inform best practices for handling puberty data.

Язык: Английский

---

A Systematic Review of Air Pollution Exposure and Brain Structure and Function during Development

Environmental Research, Год журнала: 2025, Номер unknown, С. 121368 - 121368

Опубликована: Март 1, 2025

Язык: Английский

---

Physical and mental health in adolescence: novel insights from a transdiagnostic examination of FitBit data in the ABCD study

Translational Psychiatry, Год журнала: 2024, Номер 14(1)

Опубликована: Фев. 3, 2024

Adolescence is among the most vulnerable period for emergence of serious mental illnesses. Addressing this vulnerability has generated interest in identifying markers risk symptoms and opportunities early intervention. Physical fitness been linked to psychopathology may be a useful marker target New wearable technology made assessing behavior more practical while avoiding recall self-report bias. Still, questions remain regarding clinical utility physical metrics health, both transdiagnostically along specific symptom dimensions. The current study includes 5007 adolescents (ages 10-13) who participated Adolescent Brain Cognitive Development (ABCD) additional sub-study that collected data from measures. included resting heart rate (RHR- an index cardiovascular health), time spent sedentary (associated with increased inflammation disease), moderate activity neurogenesis, neuroplasticity, healthy neurodevelopment). Self-report measures psychosis-like experiences (PLE), internalizing symptoms, externalizing symptoms. Increased RHR- lower fitness- related only greater (t = 3.63). More elevated PLE severity 5.49). -2.69) -6.29) severity. Wearable health dimensions, which emphasizes detailed digital as need precision targeting behaviors benefit psychopathology.

Язык: Английский

---

Person-Centered Social Determinants and Neighborhood-Level Deprivation Associated With Disability in Hispanic People With Multiple Sclerosis

Neurology, Год журнала: 2025, Номер 104(3)

Опубликована: Янв. 16, 2025

Multiple sclerosis (MS)-related disability in Hispanic people with MS is associated inequities social determinants of health (SDOH) as measured by composite indices areal-level census data. Studies individual-level measures SDOH are lacking. This study examined the separate and joint effects person-centered indicators an area-level on measures. diagnosed (≤5 years) who had Social Deprivation Index (SDI) based 2015-2019 American Community Survey estimates were included. At entry, data outcomes collected: Expanded Disability Status Scale (EDSS) score, Symbol Digit Modality Test (SDMT) Hauser Ambulation (HA index), 25-Foot Walk Time (25FWT). Principal component analysis was used to identify factors, mapped across a socioecological model. Multivariable regression modeling principal components (PCs) SDI outcome Of 170 participants MS, most women (71.9%) mean age at first symptom 34.01 (SD ±11.24) years diagnosis 36.27 ±10.68) years. The top 2 PCs identified represent related assimilation socioeconomic disadvantage multivariable models. In both effect models, PC1 PC2 significantly longer 25FWT (β 0.43, 95% CI 0.04-0.82, β 0.66, 0.28-1.05), higher HA index 0.22, 0.04-0.41, 0.31, 0.12-0.51), EDSS score 0.39, 0.16-0.62, 0.36, 0.13-0.60). also lower SDMT -4.15, -5.60 -2.69). models but not any measure PCs. Our findings suggest that census-based may underestimate level better markers disease severity MS. Future research policy change can focus amelioration barriers because these strongly MS-related ambulatory cognitive disability.

Язык: Английский

---