Plant-Based Copper Oxide Nanoparticles; Biosynthesis, Characterization, Antibacterial Activity, Tanning Wastewater Treatment, and Heavy Metals Sorption

Catalysts, Год журнала: 2023, Номер 13(2), С. 348 - 348

Опубликована: Фев. 3, 2023

Herein, the aqueous extract of Portulaca oleracea has been used as a safe, cheap, eco-friendly, and applicable scale-up method to bio-fabricate copper oxide nanoparticles (CuO-NPs). The character CuO-NPs were determined using UV-vis spectroscopy, Fourier transform infrared (FT-IR), X-ray diffraction (XRD), Transmission electron microscopy (TEM), Energy dispersive X-ray(EDX), Dynamic light scattering (DLS), zeta potential. Spherical crystalline with size range 5–30 nm at maximum surface plasmon resonance 275 successfully fabricated. main components green-synthesized particles Cu O weight percentages 49.92 28.45%, respectively. A Zeta-potential value −24.6 mV was recorded for CuO-NPs, indicating their high stability. plant-based showed promising antimicrobial catalytic activity in dose-dependent manner. Results that synthesized had efficacy inhibit growth pathogens Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans low MIC values ranges 6.25–25 µg/mL. highest decolorization tanning wastewater attained under sunlight irradiation conditions concentration 2.0 mg/mL after 200 min 88.6 ± 1.5% compared those which dark (70.3 1.2%). physicochemical parameters including total suspended solids (TSS), dissolved (TDS), chemical oxygen demand (COD), biological (BOD), conductivity optimum significantly decreased 95.2, 86.7, 91.4, 87.2, 97.2%, Interestingly, heavy metals cobalt (Co), lead (Pb), nickel (Ni), cadmium (Cd), chromium (Cr (VI)) 73.2, 80.8, 72.4, 64.4, 91.4%, respectively, treatment conditions. Overall, plant-synthesized have activities are considered nano-catalyst environmentally beneficial treatment.

Язык: Английский

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A Review of the Antibacterial, Fungicidal and Antiviral Properties of Selenium Nanoparticles

Materials, Год журнала: 2023, Номер 16(15), С. 5363 - 5363

Опубликована: Июль 30, 2023

The resistance of microorganisms to antimicrobial drugs is an important problem worldwide. To solve this problem, active searches for components, approaches and therapies are being carried out. Selenium nanoparticles have high potential activity. relevance their application indisputable, which can be noted due the significant increase in publications on topic over past decade. This review research aims provide reader with up-to-date information properties selenium nanoparticles, including susceptible microorganisms, mechanisms action bacteria effect nanoparticle describes most complete antiviral, antibacterial antifungal effects nanoparticles.

Язык: Английский

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Green Synthesis of Zinc Oxide Nanoparticles Using an Aqueous Extract of Punica granatum for Antimicrobial and Catalytic Activity

Journal of Functional Biomaterials, Год журнала: 2023, Номер 14(4), С. 205 - 205

Опубликована: Апрель 7, 2023

The peel aqueous extract of Punica granatum was utilized to fabricate zinc oxide nanoparticles (ZnO-NPs) as a green approach. synthesized NPs were characterized by UV-Vis spectroscopy, Fourier transform infrared (FT-IR), X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning microscopy, which attached an energy dispersive (SEM-EDX). Spherical, well arranged, crystallographic structures ZnO-NPs formed with sizes 10-45 nm. biological activities ZnO-NPs, including antimicrobial catalytic activity for methylene blue dye, assessed. Data analysis showed that the against pathogenic Gram-positive Gram-negative bacteria, unicellular fungi, observed occur in dose-dependent manner, displaying varied inhibition zones low minimum inhibitory concentration (MIC) values ranges 6.25-12.5 µg mL-1. degradation efficacy (MB) using is dependent on nano-catalyst concentration, contact time, incubation condition (UV-light emission). maximum MB percentages 93.4 ± 0.2% attained at 20 mL-1 after 210 min presence UV-light. there no significant difference between 210, 1440, 1800 min. Moreover, high stability degrade five cycles decreasing 4%. Overall, P. granatum-based are promising tools inhibit growth microbes UV-light emission.

Язык: Английский

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Exploring the antimicrobial, antioxidant, anticancer, biocompatibility, and larvicidal activities of selenium nanoparticles fabricated by endophytic fungal strain Penicillium verhagenii

Scientific Reports, Год журнала: 2023, Номер 13(1)

Опубликована: Июнь 3, 2023

Herein, four endophytic fungal strains living in healthy roots of garlic were used to produce selenium nanoparticles (Se-NPs) via green synthesis. Penicillium verhagenii was found be the most efficient Se-NPs producer with a ruby red color that showed maximum surface plasmon resonance at 270 nm. The as-formed crystalline, spherical, and well-arranged without aggregation, ranged from 25 75 nm size zeta potential value -32 mV, indicating high stability. Concentration-dependent biomedical activities P. verhagenii-based observed, including promising antimicrobial activity against different pathogens (Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, Staphylococcus aureus, Candida albicans, C. glabrata, tropicalis, parapsilosis) minimum inhibitory concentration (MIC) 12.5-100 µg mL-1. biosynthesized antioxidant DPPH-scavenging percentages 86.8 ± 0.6% 1000 mL-1 decreased 19.3 4.5% 1.95 Interestingly, also anticancer PC3 MCF7 cell lines IC50 225.7 3.6 283.8 7.5 mL-1, respectively while it is remaining biocompatible normal WI38 Vero lines. Additionally, synthesized effective instar larvae medical insect, Aedes albopictus mortality 85.1 3.1, 67.2 1.2, 62.10 1.4, 51.0 1.0% 50 for I, II, III, IV-instar larva, respectively. These data highlight efficacy cost-effective eco-friendly synthesis applications.

Язык: Английский

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Green Synthesis and Characterizations of Cobalt Oxide Nanoparticles and Their Coherent Photocatalytic and Antibacterial Investigations

Water, Год журнала: 2023, Номер 15(5), С. 910 - 910

Опубликована: Фев. 27, 2023

Water pollution is a serious concern for developing and undeveloped countries. Photocatalytic degradation of organic pollutants an effective method to restrain the green ecosystem. This research article presents green, low-cost, benevolent eco-friendly biosynthesis cobalt oxide (Co3O4) nanoparticles using Curcuma longa plant extract. The UV visible region absorbance Co3O4 estimated Co2+ Co3+ transitions on lattice oxygen, their bandgap 2.2 eV was confirmed from UV-DRS spectroscopy. cubic structure spherical shape were by XRD TEM characterizations. Plant molecules aggregation agglomerations established FTIR EDX Multiple valences oxygen surfaces reaction, bonding, binding energies analyzed XPS measurements. biogenic executed against gram-positive (Staphylococcus aureus—S. aureus) gram-negative (Escherichia coli—E. coli) bacteria. A bacterial strain exhibited great resistivity nanoparticles. Degradation dye performed methylene blue (MB) under conditions light irradiation. Dye efficiency pseudo-first-order kinetics denotes rate over MB dye. work achieved enhanced potency toxic radicals are excited irradiations. Absorption charged particle recombinations reformed provoked extract bio-molecules. In this process, there no inferior yield development, electrons robustly stimulated. Furthermore, biosynthesized determined susceptibility catalytic efficacy industrial pollutants.

Язык: Английский

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Selenium Nanoparticles: Green Synthesis and Biomedical Application

Molecules, Год журнала: 2023, Номер 28(24), С. 8125 - 8125

Опубликована: Дек. 15, 2023

Selenium nanoparticles (SeNPs) are extremely popular objects in nanotechnology. "Green" synthesis has special advantages due to the growing necessity for environmentally friendly, non-toxic, and low-cost methods. This review considers biosynthesis mechanism of bacteria, fungi, algae, plants, including role various biological substances processes reducing selenium compounds SeNPs their further packaging. Modern information approaches possible biomedical use presented: antimicrobial, antiviral, anticancer, antioxidant, anti-inflammatory, other properties, as well mechanisms these processes, that have important potential therapeutic value.

Язык: Английский

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Myco-Nanofabrication of Silver Nanoparticles by Penicillium brasilianum NP5 and Their Antimicrobial, Photoprotective and Anticancer Effect on MDA-MB-231 Breast Cancer Cell Line

Antibiotics, Год журнала: 2023, Номер 12(3), С. 567 - 567

Опубликована: Март 13, 2023

Currently, the exploration of fungal organisms for novel metabolite production and its pharmacological applications is much appreciated in biomedical field. In present study, strains were isolated from soil unexplored Yellapura regions. The potent isolate NP5 was selected based on preliminary screening identified as Penicillium brasilianum through morphological, microscopic, molecular characterizations. Synthesis silver nanoparticles P. confirmed by color change reaction mixture UV-visible surface plasmon resonance (SPR) spectra 420 nm. Fourier transform infrared (FTIR) analysis revealed functional groups involved synthesis. Atomic force microscopy (AFM) transmission electron microscope (TEM) showed aggregation NPs, with sizes ranged 10 to 60 nm, an average particle size 25.32 a polydispersity index (PDI) 0.40. crystalline nature major element NP5-AgNPs X-ray diffraction (XRD) energy dispersive (EDX) analysis. negative value -15.3 mV Zeta potential exhibited good stability, thermostability recorded thermogravimetric (TGA). antimicrobial activity human pathogens concentration-dependent manner. MTT assay anticancer IC50 41.93 µg/mL MDA-MB-231 cell line. Further, apoptotic study carried out flow cytometry observe rate apoptosis. calculated sun protection factor (SPF) confirms photoprotection capacity. From results obtained, can be used pharmaceutical field after successful vitro clinical studies.

Язык: Английский

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Antimicrobial, Antiviral, and In-Vitro Cytotoxicity and Mosquitocidal Activities of Portulaca oleracea-Based Green Synthesis of Selenium Nanoparticles

Journal of Functional Biomaterials, Год журнала: 2022, Номер 13(3), С. 157 - 157

Опубликована: Сен. 19, 2022

The aqueous extract of Portulaca oleracea was used as a biocatalyst for the reduction Na2SeO3 to form Se-NPs that appeared red in color and showed maximum surface plasmon resonance at wavelength 266 nm, indicating successful Phyto-fabrication Se-NPs. A FT-IR chart clarified role plant metabolites such proteins, carbohydrates, amino acids capping stabilizing TEM, SAED, XRD analyses indicated formation spherical, well-arranged, crystalline with sizes range 2-22 nm. SEM-EDX mapping peaks Se 1.4, 11.3, 12.4 KeV, weight atomic percentages 36.49 30.39%, respectively. zeta potential -43.8 mV also high stability synthesized Phyto-synthesized varied biological activities dose-dependent manner, including promising activity against pathogenic bacteria Candida species MIC values 12.5-50 µg·mL-1. Moreover, antiviral toward HAV Cox-B4, 70.26 62.58%, Interestingly, target orientation cancer cell lines (HepG2) low IC50 concentration 70.79 ± 2.2 µg·mL-1 compared normal (WI-38) at165.5 5.4 as-formed various instar larvae I, II, III, IV Culex pipiens, highest mortality 89 3.1, 73 1.2, 68 59 1.0%, respectively, 50 mg L-1. Thus, P. oleracea-based would be strong antimicrobial, anti-viral, anti-cancer, anti-insect agents pharmaceutical biomedical industries.

Язык: Английский

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Green Synthesis of Gold Nanoparticles by Aqueous Extract of Zingiber officinale: Characterization and Insight into Antimicrobial, Antioxidant, and In Vitro Cytotoxic Activities

Applied Sciences, Год журнала: 2022, Номер 12(24), С. 12879 - 12879

Опубликована: Дек. 15, 2022

The main challenge for researchers in the biomedical sectors concerns development of new active compounds through cost-effectiveness, rapid, simple, and ecofriendly methods to overcome antibiotic resistance pathogenic microbes. Herein, gold nanoparticles (AuNPs) were fabricated by a green approach reduction chloroauric acid (HAuCl4) harnessing metabolites present aqueous extract Zingiber officinale rhizome. UV-Vis spectroscopy, FT-IR, XRD, TEM, DLS, zeta potential used characterize phytosynthesized AuNPs. In addition, antimicrobial effect was investigated against Gram-positive bacteria (Bacillus subtilis Staphylococcus aureus), Gram-negative (Pseudomonas aeruginosa Escherichia coli), unicellular fungi (Candida albicans), multicellular (Aspergillus brasiliensis). Antioxidant vitro cytotoxic activities assessed. TEM XRD showed successful formation spherical crystalline structures, with sizes range 5–53 nm (average size: 15.11 ± 8.5 nm). value (i.e., –28.8 mV) explains high stability synthesized AuNPs exhibit promising activity prokaryotic eukaryotic microorganisms variable inhibition zones low MIC values 25–6.25 µg mL−1. Phytosynthesized DPPH scavenging percentages 87.6 0.5% at maximum concentration (1000 mL−1), which can be compared ascorbic (97.3 0.2%). Moreover, displayed target-oriented cancer cell lines HepG2 MCF7 IC50 concentrations 131.9 9.34 288.23 31.39 mL−1 normal oral epithelial OEC line (487.612 3.53 mL−1). Overall, show wide that enable their use various biotechnological applications.

Язык: Английский

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Endophytic bacterial strain,Brevibacillus brevis-mediated green synthesis of copper oxide nanoparticles, characterization, antifungal,in vitrocytotoxicity, and larvicidal activity

Green Processing and Synthesis, Год журнала: 2022, Номер 11(1), С. 931 - 950

Опубликована: Янв. 1, 2022

Abstract The biomass filtrate containing various metabolites of endophytic bacterial strain, Brevibacillus brevis PI-5 was used as a biocatalyst for reducing and stabilizing copper oxide nanoparticles (CuO-NPs). UV-Vis spectroscopy, Fourier transform infrared, transmission electron microscopy, scanning microscopy with energy-dispersive X-ray (SEM-EDX), diffraction, photoelectron spectroscopy were CuO-NPs characterization. A spherical, well-dispersed, crystallographic structure sizes 2–28 nm formed. SEM-EDX confirmed the presence Cu O weight percentages 27.62% 48.88%, respectively. biological activities including antifungal, anticancer, larvicidal synthesized assessed using fungal radial growth inhibition, MTT assay method, mortality percentages, obtained data showed that exhibit high activity in dose-dependent manner. three phytopathogenic fungi, Fusarium oxysporum, Alternaria alternata , Aspergillus niger decreased by 64.5% ± 4.1%, 62.9% 0.3%, 70.2% 2.3%, respectively at 300 µg·mL –1 . Also, clinical Candida spp. successfully inhibited varied zones inhibition minimum inhibitory concentration values ranges 6.25–50 vitro cytotoxicity exhibits target-orientation to breast cancer cells (T47D) low compared normal (HFB4) IC 50 122.3 5.4 229.9 5.7 μg·mL I, II, III, IV instar larvae Culex antennatus 60% 1.4%, 43.1% 1.1%, 36.2% 1%, 32.1% 0.9%, 10 mg·L increased 86.9% 2.1%, 68.1% 1.7%, 64.4% 1.9%, 53.1% 1.4%

Язык: Английский

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