Prevalence and Determinants of Sarcopenia Among Older Adults in India: Insights From the Longitudinal Aging Study in India
Journal of the American Geriatrics Society,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 30, 2025
Sarcopenia,
characterized
by
declining
muscle
mass
and
function,
is
a
growing
concern
among
India's
aging
population.
This
study
investigates
sarcopenia's
prevalence
determinants
using
the
nationally
representative
LASI
dataset.
analysis
included
26,780
community-dwelling
adults
aged
60
above,
with
informed
consent
obtained
from
all
participants.
Sarcopenia
was
defined
Asian
Working
Group
for
(AWGS)
2019
criteria.
Demographic,
socioeconomic,
health,
geriatric
factors,
including
age,
sex,
living
arrangements,
economic
status,
comorbidities,
syndromes,
were
examined.
Multinomial
logistic
regression
used
to
analyze
associations
sarcopenia
severe
sarcopenia,
results
expressed
as
relative
risk
ratios
(RRR)
95%
confidence
intervals
(CI).
The
of
43.6%
(n
=
11,665),
19.4%
5202)
had
sarcopenia.
Sociodemographic
factors
significantly
associated
being
widowed
(RRR:
1.24,
CI:
1.12-1.37
sarcopenia;
RRR:
1.82,
1.64-2.03
sarcopenia)
or
divorced
1.68,
1.12-2.54
sarcopenia).
Additionally,
higher
BMI
education
level
lower
Among
joint
bone
diseases
linked
both
1.21,
1.07-1.35)
1.4,
1.23-1.58),
while
hypertension
1.22,
1.1-1.36),
chronic
lung
disease
1.02-1.44),
cerebrovascular
accident
1.5,
1.09-2.08)
specifically
Geriatric
syndromes
such
tooth
loss,
impaired
vision
hearing,
history
falls,
depression
increased
reveals
significant
between
various
sociodemographic
in
older
India,
suggesting
potential
areas
targeted
intervention.
However,
further
longitudinal
studies
are
needed
validate
these
findings
clarify
causal
relationships
observed
associations.
Язык: Английский
Association between serum C-reactive protein and low muscle mass among US adults: Results from NHANES 1999 to 2006
Clinics,
Год журнала:
2025,
Номер
80, С. 100588 - 100588
Опубликована: Янв. 1, 2025
Язык: Английский
Comparative study on the association between types of physical activity, physical activity levels, and the incidence of osteoarthritis in adults: the NHANES 2007–2020
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Сен. 4, 2024
Язык: Английский
Muscle Structural and Functional Adaptations and their Osteoarthritis Linkages: Clinical and Preclinical Observations and Tentative Hypotheses
Опубликована: Авг. 24, 2024
Osteoarthritis,
the
most
prevalent
musculoskeletal
disease
affecting
older
adults
remains
an
enormous
public
health
challenge.
A
with
multiple
disabling
physical
manifestations
including
joint
tissue
damage,
inflammation
and
stiffness,
more
clearly
needs
to
be
done
retard
its
progression
emergence
wherever
possible.
Building
on
prior
reviews
capturing
almost
all
data
this
topic
2020,
here
we
present
some
newer
that
elaborates
muscle
as
a
key
structure
may
have
bearing
osteoarthritis
damage
progression.
Most
if
not
show
is
can
advance
understandings
well
mitigation
should
pursued.
Язык: Английский
Association Between Occurrence of Knee Osteoarthritis and Physical Activity in Older Adults
Journal of Health and Rehabilitation Research,
Год журнала:
2024,
Номер
4(1), С. 764 - 768
Опубликована: Фев. 17, 2024
Background:
Knee
osteoarthritis
(OA)
is
a
leading
cause
of
disability
among
older
adults,
significantly
affecting
their
quality
life
and
mobility.
The
relationship
between
physical
activity
the
severity
knee
OA
symptoms
has
been
subject
extensive
research,
with
mixed
results
on
whether
exacerbates
or
alleviates
symptoms.
Objective:
This
study
aimed
to
investigate
association
levels
osteoarthritis,
as
well
assess
impact
health-related
individuals
OA.
Methods:
A
cross-sectional
was
conducted
171
patients
diagnosed
at
four
medical
institutions.
Data
demographics,
levels,
were
collected
through
standardized
questionnaires,
including
SF-36
Health
Survey
injury
Osteoarthritis
Outcome
Score
(KOOS).
Physical
categorized
poor,
moderate,
good.
classified
no
OA,
moderate
extreme
Statistical
analysis
performed
using
SPSS
version
25,
employing
descriptive
statistics,
chi-square
tests
for
categorical
variables,
Pearson's
correlation
severity.
Results:
population
comprised
35.1%
males
64.9%
females,
mean
age
71.1±3.9
years.
Regarding
activity,
30.4%
engaged
in
46.8%
22.8%
good
activity.
reported
25.1%
patients,
49.1%,
absent
25.7%.
revealed
significant
(Pearson
Chi-Square
=
.000),
indicating
that
higher
associated
lower
Conclusion:
supports
notion
engaging
reduced
suggests
could
be
beneficial
managing
improving
These
findings
highlight
importance
promoting
key
component
management
strategies.
Язык: Английский
Cross-sectional study on the relationship between Body Mass Index and severity of knee osteoarthritis
Mohd. Shifa Hasan,
Aditya Kumar Mishra,
Mohd Bilal Kaleem
и другие.
Romanian Journal of Rheumatology,
Год журнала:
2024,
Номер
33(1), С. 48 - 53
Опубликована: Март 31, 2024
Background.
Musculoskeletal
diseases
like
osteoarthritis
(OA)
are
widespread.
OA
affects
the
knees,
makes
joints
wear
out
and
hurt,
it
hard
to
move
around.
Body
mass
index
(BMI)
is
a
way
measure
obesity,
which
linked
higher
chance
of
getting
making
worse.
The
main
aim
this
cross-sectional
study
was
find
how
body
related
lousy
knee
is.
Methods.
One
hundred
people
at
Shri
Guru
Ram
Rai
Institute
Medical
Health
Sciences
in
Dehradun
met
study’s
requirements
were
enrolled.
Kellgren-Lawrence
grading
method
used
severity
(OA),
standard
measurements
calculate
(BMI).
A
correlation
done
examine
link
between
BMI
OA.
Results.
sample
included
100
participants
on
average
60
years
old.
typical
symptoms
lasted
five
years.
distribution
analysis
showed
35%
obese,
40%
overweight,
25%
underweight
or
weight.
Twenty
percent
patients
mild,
35
intermediate,
30
severe,
15
progressed.
association
investigation
revealed
significant
positive
(r
=
0.65,
p
<
0.001).
Conclusion.
Our
results
show
that
being
overweight
can
worsen
OA,
proving
with
problem
need
watch
their
If
we
treat
obesity
as
risk
factor
be
changed,
might
able
improve
Язык: Английский
Association of sarcopenia and its prognostic value in symptomatic knee osteoarthritis among older people in China: the first longitudinal evidence from CHARLS
BMC Geriatrics,
Год журнала:
2024,
Номер
24(1)
Опубликована: Ноя. 28, 2024
Sarcopenia
and
knee
osteoarthritis
(KOA)
are
two
common
musculoskeletal
disorders,
often
coexisting
in
aged
population
potentially
influencing
each
other.
However,
the
underlying
relationship
between
conditions
remains
unclear
controversial.
To
fill
this
knowledge
gap,
we
aimed
to
investigate
longitudinal
association
among
older
Chinese
population.
Data
were
attracted
from
2
waves
of
China
Health
Retirement
Longitudinal
Study
(CHARLS),
6212
individuals
≥
60
years
included.
status
was
defined
by
Asian
Working
Group
for
2019
criteria.
Multivariate
logistic
regression
generalized
estimation
equation
models
applied
estimate
impact
sarcopenia
on
KOA.
A
prognostic
nomogram
developed
through
train-test
cross-validation.
At
baseline
CHARLS
2015,
prevalence
symptomatic
KOA
12.7%
(792/6212)
total
population,
9%
(270/2996)
no-sarcopenia
group,
17.5%
(286/1638)
possible
15.0%
(236/1578)
group.
Over
a
3-year
follow-up,
4980
respondents
included,
with
incident
cases
identified
as
56
(2.2%),
38
(3.0%),
43
(3.6%)
no-sarcopenia,
sarcopenia,
groups,
respectively.
significantly
associated
increased
new-onset
compared
peers
fully
adjusted
model
(OR:
1.91,
95%
CI:
1.15–3.18),
whereas
non-significant
sarcopenia.
In
females,
low
muscle
mass
alone
risk
2.58,
1.05–6.49).
The
final
nomogram,
including
status,
age,
gender,
body
index,
self-reported
health
comorbidities,
history
falls
physical
activity,
had
considerable
discrimination
(AUC
=
0.744,
C-index
0.660).
calibration
curve
indicated
significant
agreement
predicted
actual
observations.
Decision
analysis
revealed
net
benefits
clinical
intervention
at
probability
threshold
1–17%.
higher
KOA,
wherein
may
play
an
important
role.
inferior
prognosis
needs
more
attention
practice.
Язык: Английский
Kashin–Beck Disease: A Risk Factor for Sarcopenia and Its Interaction with Selenium
Nutrients,
Год журнала:
2024,
Номер
16(24), С. 4343 - 4343
Опубликована: Дек. 16, 2024
Objectives:
We
aimed
to
explore
the
possible
effects
of
Kashin–Beck
disease
(KBD)
on
risk
sarcopenia
and
its
interaction
in
association
between
element
concentration.
Methods:
This
cross-sectional
study
was
conducted
among
individuals
18–75
years
old
Qamdo,
a
KBD-endemic
area.
All
received
physical
radiological
examinations
before
recruitment.
Patients
with
KBD
were
enrolled
group
based
diagnosis
national
criteria
WS/T
207-2010.
Healthy
without
non-KBD
group.
Participants
history
supplements,
other
severe
musculoskeletal
diseases,
or
organ
dysfunctions
excluded.
adopted
WOMAC
scores
for
assessment
conditions
SARC-F
sarcopenia.
≥
4
at
Serum
concentrations
analyzed
by
inductively
coupled
plasma
mass
spectrometry.
Dose–relationship
clinical
determined
correlation
analysis.
Risk
factors
identified
using
univariate
multivariate
regression.
Statistical
analysis
R
software.
Results:
A
total
65
patients
38
participants
After
propensity
score
matching,
population
characteristics
comparable
two
groups,
incidence
be
higher
(p
=
0.002).
The
correlated
<
0.001)
group,
respectively.
Further
proved
that
independent
factor
0.014).
Moreover,
high
Selenium
associated
low
0.047),
while
this
not
observed
0.239).
Conclusions:
as
an
increased
patients.
Although
Se
concentration
KBD,
those
KBD.
Язык: Английский