Medical Hypotheses, Год журнала: 2024, Номер 190, С. 111429 - 111429
Опубликована: Июль 11, 2024
Язык: Английский
Medical Hypotheses, Год журнала: 2024, Номер 190, С. 111429 - 111429
Опубликована: Июль 11, 2024
Язык: Английский
Science China Life Sciences, Год журнала: 2025, Номер unknown
Опубликована: Янв. 13, 2025
Язык: Английский
Процитировано
0Journal of Drug Delivery Science and Technology, Год журнала: 2024, Номер 100, С. 106076 - 106076
Опубликована: Авг. 23, 2024
Язык: Английский
Процитировано
2Kazan medical journal, Год журнала: 2024, Номер 105(5), С. 813 - 824
Опубликована: Окт. 2, 2024
The review summarized the literature data of recent years on antitumor effect secondary plant metabolites, as well their immunotropic and anti-inflammatory effects components response. biological basis for action metabolites was characterized in form influence potential targets: transcription factors, signaling pathways receptors responsible proliferation apoptosis. ways increasing bioavailability to enhance effectiveness possibility medicinal use were considered, berberine, curcumin derivatives described. search scientific publications conducted foreign (PubMed) domestic (eLibrary) electronic libraries. It found that multiplicity molecular targets pleiotropy suggest regulation various processes tumor normal cells. There a connection between immunomodulatory action. However, significant limitation fact most studies cell cultures, which insufficient judge effect. Clinical trials few results contradictory. In addition, certain contradiction has been noted idea more effective when using pure substance or complex composition components. An important problem low methods have proposed. Despite long history phytotherapy oncology, development new with high water solubility remains relevant, including modified molecules known ones unexplored activity. Modern chemical synthesis delivery systems study model experiments, seem be promising directions creation drugs
Язык: Английский
Процитировано
2Medical Hypotheses, Год журнала: 2024, Номер 190, С. 111429 - 111429
Опубликована: Июль 11, 2024
Язык: Английский
Процитировано
0