Research Directions Depression, Год журнала: 2025, Номер 2
Опубликована: Янв. 1, 2025
Abstract Research into the causes of mood disorders has been going on for decades. However, most hypotheses put forward have insufficiently substantiated by living biomarkers. Much research is therefore being conducted biomarkers that help us better assess diagnosis and course disorders. Neural autoantibodies are one such biomarker potentially appearing in a subgroup The aim this narrative review to describe spectrum while substantiating their prevalence, about which there very inconsistent evidence. In addition, we discuss context systemic autoimmune diseases associated with depressive symptoms. pathogenicity individual occasionally demonstrated animal models, evidence severity symptoms correlates certain autoantibodies. Possible models autoimmunity also explained, as involvement B-cell system, complement inflammation processes. Nevertheless, note mere presence does not justify assumption an genesis, more needed. concepts behind targeting
Язык: Английский
