Analysis of the characteristics of mixed infections with Mycoplasma pneumoniae in children

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Март 19, 2025

353 hospitalized children diagnosed with Mycoplasma pneumoniae (MP) pneumonia were included in the study. They divided into MP co-infection group and single infection group. 143 (40.5%) of enrolled had co-infections. The most common co-infecting pathogen was Rhinovirus (30.8%). Among co-infections, 82 cases (57.3%) involved one pathogen, 44 (30.7%) two pathogens, 12 (8.4%) three 4 (2.8%) four 1 case (0.7%) five pathogens. Significant differences observed between groups terms severe pneumonia, macrolide resistance, bronchial mucus plug, hormone use, P-values 0.039, 0.000, 0.035. mixed virus or bacteria more likely to develop drug resistance compared (P = 0.007 P 0.046). 0.032 0.017). In conclusion, commonly co-infected Rhinovirus. Children co-infections tend exhibit higher rates require frequent use hormones, are plug.

Язык: Английский

Clinical utility of metagenomic next-generation sequencing in pathogen detection for lower respiratory tract infections

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Май 30, 2025

Язык: Английский