Association between relative fat mass and female infertility among reproductive-aged women from NHANES 2013–2020 DOI Creative Commons
Yiming Chen, Yuanyuan Li,

Bo Zhang

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Апрель 17, 2025

Female infertility is a prevalent condition closely linked with obesity. Current evaluation metrics like body mass index (BMI) and waist circumference (WC) have limitations. Relative fat (RFM) newer, more accurate obesity metric, but its relationship lacks research. Data from 3489 female participants aged 18-45 years the NHANES 2013-2020 cycles were extracted analyzed. Infertility was assessed based on participants' pregnancy attempts medical consultations. The primary exposure variables BMI, WC, RFM. Survey-weighted logistic regression models conducted to compare their associations infertility, expressed as odds ratios (ORs). RFM further categorized into quartiles for additional analysis. Subgroup analyses evaluate whether association between differs across key demographic clinical factors, including age, race, PIR, education level, smoking status, DM, hypertension, age at menarche, history of pelvic inflammatory disease (PID). Restricted cubic splines (RCS) employed robustness linearity assessments. Our results showed an prevalence 13.41%, affected women being older having higher BMI. OR (1.039, 95% CI: 1.010, 1.068) in analysis fully adjusted Model than BMI (1.020, 1.002, 1.039) WC (1.014, 1.006, 1.022), indicating that each unit increase correlates risk infertility. Similarly, quartile indicated increased (Q2: = 1.66, 1.05, 2.64; Q3: 1.79, 1.16, 2.74; Q4: 2.23, 1.38, 3.60). Additionally, consistent supplementary subgroup without interaction, RCS confirmed linear relationship. findings demonstrate significant population-based sample, supporting hypothesis excess adiposity may play role reproductive health. Further research needed explore mechanisms broader applications

Язык: Английский

Association between relative fat mass and female infertility among reproductive-aged women from NHANES 2013–2020 DOI Creative Commons
Yiming Chen, Yuanyuan Li,

Bo Zhang

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Апрель 17, 2025

Female infertility is a prevalent condition closely linked with obesity. Current evaluation metrics like body mass index (BMI) and waist circumference (WC) have limitations. Relative fat (RFM) newer, more accurate obesity metric, but its relationship lacks research. Data from 3489 female participants aged 18-45 years the NHANES 2013-2020 cycles were extracted analyzed. Infertility was assessed based on participants' pregnancy attempts medical consultations. The primary exposure variables BMI, WC, RFM. Survey-weighted logistic regression models conducted to compare their associations infertility, expressed as odds ratios (ORs). RFM further categorized into quartiles for additional analysis. Subgroup analyses evaluate whether association between differs across key demographic clinical factors, including age, race, PIR, education level, smoking status, DM, hypertension, age at menarche, history of pelvic inflammatory disease (PID). Restricted cubic splines (RCS) employed robustness linearity assessments. Our results showed an prevalence 13.41%, affected women being older having higher BMI. OR (1.039, 95% CI: 1.010, 1.068) in analysis fully adjusted Model than BMI (1.020, 1.002, 1.039) WC (1.014, 1.006, 1.022), indicating that each unit increase correlates risk infertility. Similarly, quartile indicated increased (Q2: = 1.66, 1.05, 2.64; Q3: 1.79, 1.16, 2.74; Q4: 2.23, 1.38, 3.60). Additionally, consistent supplementary subgroup without interaction, RCS confirmed linear relationship. findings demonstrate significant population-based sample, supporting hypothesis excess adiposity may play role reproductive health. Further research needed explore mechanisms broader applications

Язык: Английский

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