The relationship between dietary inflammatory index in adults and coronary heart disease: from NHANES 1999–2018 DOI Creative Commons
Xu Hong, Pengxin Xie, Hui Liu

и другие.

Frontiers in Nutrition, Год журнала: 2025, Номер 12

Опубликована: Март 21, 2025

Background Previous studies have shown that pro-inflammatory diets increase the risk of coronary heart disease (CHD) and all-cause mortality. The dietary inflammatory index (DII) is a quantitative measure inflammation, its accuracy has been validated by several studies. Methods This study included 43,842 participants aged ≥18 years from National Health Nutrition Examination Survey (NHANES) 1999–2018. data CHD was obtained through questionnaire survey, DII calculated using 24-h recall data. Generalized linear models logistic regression were used to determine mediation factors, subgroup analyses conducted evaluate interaction between CHD. Mean decrease in Gini (MDG) importance individual components. Results age 49.81 ± 18.10 years, with 20,793 (47.4%) being male. A total 1,892 (4.3%) diagnosed CHD, median score 1.33 (0.11, 2.40). After adjusting for potential confounders, analysis revealed independently associated [OR: 1.049 (1.012–1.087), p = 0.008]. Triglyceride-glucose index, visceral adiposity body mass waist-to-height ratio, high-density lipoprotein, glomerular filtration rate (all < 0.05) may mediate relationship Subgroup showed more sensitive <75 ( 0.001), females 0.028), those low cholesterol levels 0.004), individuals Framingham scores 0.005). MDG indicated carbohydrate, vitamin C iron intake greatest impact on Conclusion suggests various metabolic lipid indicators play mediating role greater adverse traditional low-risk populations.

Язык: Английский

The relationship between dietary inflammatory index in adults and coronary heart disease: from NHANES 1999–2018 DOI Creative Commons
Xu Hong, Pengxin Xie, Hui Liu

и другие.

Frontiers in Nutrition, Год журнала: 2025, Номер 12

Опубликована: Март 21, 2025

Background Previous studies have shown that pro-inflammatory diets increase the risk of coronary heart disease (CHD) and all-cause mortality. The dietary inflammatory index (DII) is a quantitative measure inflammation, its accuracy has been validated by several studies. Methods This study included 43,842 participants aged ≥18 years from National Health Nutrition Examination Survey (NHANES) 1999–2018. data CHD was obtained through questionnaire survey, DII calculated using 24-h recall data. Generalized linear models logistic regression were used to determine mediation factors, subgroup analyses conducted evaluate interaction between CHD. Mean decrease in Gini (MDG) importance individual components. Results age 49.81 ± 18.10 years, with 20,793 (47.4%) being male. A total 1,892 (4.3%) diagnosed CHD, median score 1.33 (0.11, 2.40). After adjusting for potential confounders, analysis revealed independently associated [OR: 1.049 (1.012–1.087), p = 0.008]. Triglyceride-glucose index, visceral adiposity body mass waist-to-height ratio, high-density lipoprotein, glomerular filtration rate (all < 0.05) may mediate relationship Subgroup showed more sensitive <75 ( 0.001), females 0.028), those low cholesterol levels 0.004), individuals Framingham scores 0.005). MDG indicated carbohydrate, vitamin C iron intake greatest impact on Conclusion suggests various metabolic lipid indicators play mediating role greater adverse traditional low-risk populations.

Язык: Английский

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