A standardized nomenclature for the rods and cones of the vertebrate retina

PLoS Biology, Год журнала: 2025, Номер 23(5), С. e3003157 - e3003157

Опубликована: Май 7, 2025

Vertebrate photoreceptors have been studied for well over a century, but fixed nomenclature referring to orthologous cell types across diverse species has lacking. Instead, variably—and often confusingly—named according morphology, presence/absence of ‘rhodopsin’, spectral sensitivity, chromophore usage, and/or the gene family opsin(s) they express. Here, we propose unified vertebrate rods and cones that aligns with naming systems other retinal classes is based on photoreceptor type’s putative evolutionary history. This classification informed by functional, anatomical, developmental, molecular identities neuron as whole, including expression deeply conserved transcription factors required development. The proposed names will be applicable all vertebrates indicative widest possible range properties, their postsynaptic wiring, hence allude common species-specific roles in vision. Furthermore, system open-ended accommodate future discovery as-yet unknown types.

Язык: Английский

---

Vertebrate vision: New light on the enigmatic double cone

Current Biology, Год журнала: 2025, Номер 35(10), С. R382 - R384

Опубликована: Май 1, 2025

Язык: Английский

---