Developments in neuroethics and bioethics, Год журнала: 2024, Номер unknown, С. 167 - 189
Опубликована: Янв. 1, 2024
Язык: Английский
Journal of Neurology, Год журнала: 2024, Номер 271(5), С. 2258 - 2273
Опубликована: Фев. 17, 2024
Язык: Английский
Процитировано
28
Polymer-Plastics Technology and Materials, Год журнала: 2024, Номер 63(6), С. 680 - 702
Опубликована: Янв. 10, 2024
The emergence of Polyether Ether Ketone (PEEK) in implant fabrication is a sign the revolution healthcare that has been sparked by convergence 3D printing technology and advanced materials. This review paper investigates multifaceted impact PEEK on changing manufacturing landscape. explores significance fabrication, critical function printing, as leading material through thorough analysis PEEK's exceptional biocompatibility, mechanical properties, adaptability. It various PEEK-based applications dental, orthopedic, spinal, cranial, cardiovascular, emerging domains, supported real-world case studies success stories. also discusses difficulties, developments, sustainability issues related to printing. revolutionary highlighted this paper, which charts future directions provides insights into how patient care paradigm implantology.
Язык: Английский
Процитировано
16
Nature Communications, Год журнала: 2025, Номер 16(1)
Опубликована: Янв. 2, 2025
Язык: Английский
Процитировано
2
ACS Nano, Год журнала: 2023, Номер 17(11), С. 9661 - 9672
Опубликована: Май 17, 2023
Development and implementation of neuroprosthetic hands is a multidisciplinary field at the interface between humans artificial robotic systems, which aims replacing sensorimotor function upper-limb amputees as their own. Although prosthetic hand devices with myoelectric control can be dated back to more than 70 years ago, applications anthropomorphic mechanisms sensory feedback functions are still relatively preliminary laboratory stage. Nevertheless, recent series proof-of-concept studies suggest that soft robotics technology may promising useful in alleviating design complexity dexterous mechanism integration difficulty multifunctional skins, particular, context personalized applications. Here, we review evolution emerging cutting-edge robotics, covering relating bidirectional neural interactions feedback. We further discuss future opportunities on revolutionized mechanisms, high-performance sensors, compliant neural-interaction interfaces for next generation hands.
Язык: Английский
Процитировано
29
Journal of Neuroscience, Год журнала: 2024, Номер 44(1), С. e1051232024 - e1051232024
Опубликована: Янв. 3, 2024
Despite the increasing incidence and prevalence of amputation across globe, individuals with acquired limb loss continue to struggle functional recovery chronic pain. A more complete understanding motor sensory remodeling peripheral central nervous system that occurs postamputation may help advance clinical interventions improve quality life for loss. The purpose this article is first provide background context on then a comprehensive review known neural adaptations from both animal models human trials. Finally, bridges gap between basic science researchers clinicians treat by explaining how current treatments restore function modulate phantom pain using underlying described above. This should encourage further development novel neurological targets postamputation. Significance Statement In United States, 1.6 million people live loss; number expected than double 2050. Improved surgical procedures enhance recovery, new prosthetics interfaces can replace missing limbs those communicate bidirectionally brain. These advances have been fairly successful, but still most patients experience persistent problems like pain, others discontinue prostheses instead learning use them daily. problematic patient outcomes be due in part lack consensus among regarding plasticity mechanisms occur brain after injuries. Here we results model studies bridge clinicalbasic gap.
Язык: Английский
Процитировано
11
Frontiers in Neuroscience, Год журнала: 2024, Номер 18
Опубликована: Март 7, 2024
Despite considerable advancement of first choice treatment (pharmacological, physical therapy, etc.) over many decades, neurological disorders still represent a major portion the worldwide disease burden. Particularly concerning, trend is that this scenario will worsen given an ever expanding and aging population. The different methods brain stimulation (electrical, magnetic, are, on other hand, one most promising alternatives to mitigate suffering patients families when conventional fall short delivering efficacious treatment. With applications in virtually all conditions, neurostimulation has seen success providing relief symptoms. On large variability therapeutic outcomes also been observed, particularly usage non-invasive (NIBS) modalities. Borrowing inspiration concepts from its pharmacological counterpart empowered by unprecedented neurotechnological advancement, field recent years widespread aimed at personalization parameters, based biomarkers individuals being treated. rationale that, taking into account important factors influencing outcome, personalized can yield much-improved therapy. Here, we review literature delineate state-of-the-art stimulation, while considering aspects type informing parameter (anatomy, function, hybrid), invasiveness, level development (pre-clinical experimentation versus clinical trials). Moreover, reviewing relevant closed loop neuroengineering solutions general activity dependent method particular, put forward idea improved may be achieved able track real time dynamics adjust parameters accordingly. We conclude such approaches have great potential promoting recovery lost functions enhance quality life for patients.
Язык: Английский
Процитировано
9
Advanced Materials, Год журнала: 2025, Номер unknown
Опубликована: Янв. 21, 2025
Abstract Mechanical information is a medium for perceptual interaction and health monitoring of organisms or intelligent mechanical equipment, including force, vibration, sound, flow. Researchers are increasingly deploying recognition technologies (MIRT) that integrate acquisition, pre‐processing, processing functions expected to enable advanced applications. However, this also poses significant challenges acquisition performance efficiency. The novel exciting mechanosensory systems in nature have inspired us develop superior bionic (MIBRT) based on materials, structures, devices address these challenges. Herein, first strategies pre‐processing presented their importance high‐performance highlighted. Subsequently, design considerations sensors by mechanoreceptors described. Then, the concepts neuromorphic summarized order replicate biological nervous system. Additionally, ability MIBRT investigated recognize basic information. Furthermore, further potential applications robots, healthcare, virtual reality explored with view solve range complex tasks. Finally, future opportunities identified from multiple perspectives.
Язык: Английский
Процитировано
1
Frontiers in Neurology, Год журнала: 2024, Номер 15
Опубликована: Фев. 14, 2024
In recent years, artificial intelligence (AI) has undergone remarkable advancements, exerting a significant influence across multitude of fields. One area that particularly garnered attention and witnessed substantial progress is its integration into the realm nervous system. This article provides comprehensive examination AI’s applications within peripheral system, with specific focus on AI-enhanced diagnostics for system disorders, AI-driven pain management, advancements in neuroprosthetics, development neural network models. By illuminating these facets, we unveil burgeoning opportunities revolutionary medical interventions enhancement human capabilities, thus paving way future which AI becomes an integral component our system’s interface.
Язык: Английский
Процитировано
7
Biomimetics, Год журнала: 2024, Номер 9(5), С. 273 - 273
Опубликована: Апрель 30, 2024
Recent advancements in biomimetics have spurred significant innovations prosthetic limb development by leveraging the intricate designs and mechanisms found nature. Biomimetics, also known as “nature-inspired engineering”, involves studying emulating biological systems to address complex human challenges. This comprehensive review provides insights into latest trends biomimetic prosthetics, focusing on knowledge from natural biomechanics, sensory feedback mechanisms, control closely mimic appendages. Highlighted breakthroughs include integration of cutting-edge materials manufacturing techniques such 3D printing, facilitating seamless anatomical limbs. Additionally, incorporation neural interfaces enhances movement, while technologies like scanning enable personalized customization, optimizing comfort functionality for individual users. Ongoing research efforts hold promise further advancements, offering enhanced mobility individuals with loss or impairment. illuminates dynamic landscape technology, emphasizing its transformative potential rehabilitation assistive technologies. It envisions a future where solutions seamlessly integrate body, augmenting both quality life.
Язык: Английский
Процитировано
7
AI and Ethics, Год журнала: 2024, Номер unknown
Опубликована: Март 20, 2024
Язык: Английский
Процитировано
6