Prolonged
exposure
to
weak
(~1
μT)
extremely-low-frequency
(ELF,
50/60
Hz)
magnetic
fields
has
been
associated
with
an
increased
risk
of
childhood
leukaemia.
One
the
few
biophysical
mechanisms
that
might
account
for
this
link
involves
short-lived
chemical
reaction
intermediates
known
as
radical
pairs.
In
report,
we
use
spin
dynamics
simulations
derive
upper
bound
10
parts
per
million
on
effect
a
1
μT
ELF
field
yield
pair
reaction.
By
comparing
figure
corresponding
effects
changes
in
strength
Earth’s
field,
conclude
if
such
Hz
any
human
biology,
and
results
from
mechanism,
then
should
be
no
greater
than
travelling
kilometres
towards
or
away
geomagnetic
north
south
pole.
The Journal of Physical Chemistry Letters,
Год журнала:
2020,
Номер
11(7), С. 2414 - 2421
Опубликована: Март 6, 2020
A
visual
magnetic
sense
in
migratory
birds
has
been
hypothesized
to
rely
on
a
radical
pair
reaction
the
protein
cryptochrome.
In
this
model,
sensitivity
originates
from
coherent
spin
dynamics,
as
radicals
couple
nuclei
via
hyperfine
interactions.
Prior
studies
have
often
neglected
electron–electron
dipolar
(EED)
coupling
hypothesis.
We
show
that
EED
interactions
suppress
anisotropic
response
geomagnetic
field
by
mechanism
cryptochrome
and
attenuation
is
unlikely
be
mitigated
mutual
cancellation
of
electronic
exchange
coupling,
previously
suggested.
then
demonstrate
limitation
may
overcome
extending
conventional
model
include
third,
nonreacting
radical.
predict
effects
could
work
concert
with
three-radical
tailor
superior
response,
thereby
providing
new
principle
for
magnetosensitivity
applications
sensing,
navigation,
assessment
biological
effects.
New Journal of Physics,
Год журнала:
2021,
Номер
23(4), С. 043032 - 043032
Опубликована: Март 9, 2021
Abstract
That
the
rates
and
yields
of
reactions
organic
radicals
can
be
spin
dependent
is
well
known
in
context
radical
pair
mechanism
(RPM).
Less
known,
but
still
established,
chiral-induced
selectivity
(CISS)
effect
which
chiral
molecules
act
as
filters
that
preferentially
transmit
electrons
with
spins
polarized
parallel
or
antiparallel
to
their
direction
motion.
Starting
from
assumption
CISS
arise
electron
transfer
pairs,
we
propose
a
simple
way
include
conventional
models
dynamics.
We
show
(a)
increase
sensitivity
pairs
weak
external
magnetic
field,
(b)
change
dependence
field
on
reaction
rate
constants,
(c)
destroy
field-inversion
symmetry
characteristic
RPM.
argue
polarization
effects
could
observable
by
EPR
(electron
paramagnetic
resonance)
oriented
samples
either
differences
continuous
wave,
time-resolved
spectra
recorded
spectrometer
perpendicular
quantization
axis
signals
in-phase
channel
an
out-of-phase
ESEEM
echo
envelope
modulation)
experiment.
Finally
assess
whether
might
relevant
hypothesis
compass
migratory
songbirds
relies
photochemically-formed
cryptochrome
flavoproteins.
Although
offer
possibility
evolving
more
sensitive
precise
compass,
associated
lack
has
not
hitherto
been
observed
behavioural
experiments.
In
addition,
it
may
no
longer
safe
assume
observation
polar
response
animal
used
evidence
against
sensory
mechanism.
Scientific Reports,
Год журнала:
2022,
Номер
12(1)
Опубликована: Янв. 7, 2022
Drosophila's
circadian
clock
can
be
perturbed
by
magnetic
fields,
as
well
lithium
administration.
Cryptochromes
are
critical
for
the
clock.
Further,
radical
pairs
in
cryptochrome
also
explain
magnetoreception
animals.
Based
on
a
simple
pair
mechanism
model
of
animal
compass,
we
show
that
both
fields
and
influence
spin
dynamics
naturally
occurring
hence
modulate
clock's
rhythms.
Using
chemical
oscillator
clock,
rate
model,
which
translates
into
change
period.
Our
reproduce
results
two
independent
experiments,
field
effects
predicts
stronger
would
shorten
We
predict
influences
an
isotope-dependent
manner.
Furthermore,
our
hyperfine
interactions
oxidative
stress.
The
findings
this
work
suggest
quantum
nature
might
play
roles
brain,
another
piece
evidence
addition
to
recent
xenon
anesthesia
hyperactivity.
Electromagnetic Biology and Medicine,
Год журнала:
2022,
Номер
41(3), С. 293 - 303
Опубликована: Май 11, 2022
The
potential
therapeutic
uses
of
electromagnetic
fields
(EMF),
part
the
nonionizing
radiation
spectrum,
increase
with
time.
Among
them,
those
considering
antitumor
effects
exerted
by
Magnetic
Fields
(MFs),
EMF
entity,
have
gained
more
and
interest.
A
recent
review
on
this
subject
reports
MFs'
effect
apoptosis
tumor
cells
as
one
most
important
breakthroughs.
Apoptosis
is
considered
a
key
mechanism
regulating
genetic
stability
such
fundamental
importance
in
cancer
initiation
development.
According
to
an
atomic/sub-atomic
analysis,
based
quantum
physics,
complexity
biological
life
role
played
oxygen
its
radicals
biology,
possible
biophysical
described.
considers
influence
MFs
through
electron
spin
that
able
reactive
species
(ROS)
concentration.
Impacting
delicate
balance
between
ROS
production
elimination
promising
therapy,
affecting
different
processes,
metastasis.
An
analysis
literature,
which
allows
correlation
exposure
characteristics
their
concentration,
supports
validity
mechanism.
Prolonged
exposure
to
weak
(~1
μT)
extremely-low-frequency
(ELF,
50/60
Hz)
magnetic
fields
has
been
associated
with
an
increased
risk
of
childhood
leukaemia.
One
the
few
biophysical
mechanisms
that
might
account
for
this
link
involves
short-lived
chemical
reaction
intermediates
known
as
radical
pairs.
In
report,
we
use
spin
dynamics
simulations
derive
upper
bound
10
parts
per
million
on
effect
a
1
μT
ELF
field
yield
pair
reaction.
By
comparing
figure
corresponding
effects
changes
in
strength
Earth’s
field,
conclude
if
such
Hz
any
human
biology,
and
results
from
mechanism,
then
should
be
no
greater
than
travelling
kilometres
towards
or
away
geomagnetic
north
south
pole.
