In Situ Electrospinning of Aggregation‐Induced Emission Nanofibrous Dressing for Wound Healing DOI
Ruihua Dong, Ying Li, Mian Chen

и другие.

Small Methods, Год журнала: 2022, Номер 6(5)

Опубликована: Фев. 26, 2022

Rapid wound dressing and effective antibacterial therapy that meet the extreme requirements of emergency situations are urgently needed for treating skin wounds. Here, an in situ deposited personalized nanofibrous is reported which can be directly electrospun on wounds by a handheld electrospinning device perfectly fits different various sizes. Moreover, aggregation-induced emission luminogen with photodynamic effect loaded dressings endows dressing's long-term activity during healing process. The nanofibers show excellent antimicrobial against Staphylococcus aureus (S. aureus) methicillin-resistant aureus. In vivo studies demonstrate these effectively reduce inflammation significantly accelerate healing. Such produced promising as total solution emergencies, including patient-specific clinical military injuries.

Язык: Английский

Drug delivery systems and materials for wound healing applications DOI

Saghi Saghazadeh,

Chiara Rinoldi, Maik Schot

и другие.

Advanced Drug Delivery Reviews, Год журнала: 2018, Номер 127, С. 138 - 166

Опубликована: Март 1, 2018

Язык: Английский

Процитировано

690

Electrospinning for drug delivery applications: A review DOI Creative Commons
Andrea Luraghi, Francesco Peri, Lorenzo Moroni

и другие.

Journal of Controlled Release, Год журнала: 2021, Номер 334, С. 463 - 484

Опубликована: Март 27, 2021

Drug delivery devices are promising tools in the pharmaceutical field, as they able to maximize therapeutic effects of delivered drug while minimizing undesired side effects. In past years, electrospun nanofibers attracted rising attention due their unique features, like biocompatibility and broad flexibility. Incorporation active principles nanofibrous meshes proved be an efficient method for situ a wide range drugs, expanding possibility applicability those devices. this review, principle electrospinning different fields applications treated give overview recent literature, underlining easy tuning endless combination technique, that future could new frontier personalized medicine.

Язык: Английский

Процитировано

555

Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis DOI Creative Commons
Hamed Nosrati,

Reza Aramideh Khouy,

Ali Nosrati

и другие.

Journal of Nanobiotechnology, Год журнала: 2021, Номер 19(1)

Опубликована: Янв. 4, 2021

Abstract Skin is the body’s first barrier against external pathogens that maintains homeostasis of body. Any serious damage to skin could have an impact on human health and quality life. Tissue engineering aims improve damaged tissue regeneration. One most effective treatments for regeneration angiogenesis during healing period. Over last decade, there has been impressive growth new potential applications nanobiomaterials in engineering. Various approaches developed rate process using angiogenic nanomaterials. In this review, we focused molecular mechanisms key factors angiogenesis, role scaffold-based accelerated wound based improved angiogenesis.

Язык: Английский

Процитировано

537

Hydrogel Based Sensors for Biomedical Applications: An Updated Review DOI Open Access
Javad Tavakoli, Youhong Tang

Polymers, Год журнала: 2017, Номер 9(8), С. 364 - 364

Опубликована: Авг. 16, 2017

Biosensors that detect and convert biological reactions to a measurable signal have gained much attention in recent years. Between 1950 2017, more than 150,000 papers been published addressing the applications of biosensors different industries, but best our knowledge through careful screening, critical reviews describe hydrogel based for biomedical are rare. This review discusses application biosensors, on search performed Web Science Core, PubMed (NLM), Direct online databases years 2000–2017. In this review, we consider bioreceptors be immobilized their advantages disadvantages, immobilization techniques. We identify hydrogels most favored type biosensor, as well predominant transduction strategies. explain including cell metabolite pathogen detection, tissue engineering, wound healing, cancer monitoring, strategies small biomolecules such glucose, lactate, urea, cholesterol detection identified.

Язык: Английский

Процитировано

365

Latest Progress in Electrospun Nanofibers for Wound Healing Applications DOI
Adnan Memić, Turdimuhammad Abdullah,

Halimatu S. Mohammed

и другие.

ACS Applied Bio Materials, Год журнала: 2019, Номер 2(3), С. 952 - 969

Опубликована: Янв. 31, 2019

Electrospinning is a versatile technique used to create native tissue-like fibrous scaffolds. Recently, it has gained large amount of attention for generation bioactive dressing materials suitable treatment both chronic and acute wounds. In this Review, we focus on the latest advances made in application electrospun scaffolds wound healing. We first provide brief overview healing process electrospinning approaches. then discuss fabrication from natural synthetic polymers via effective management. Natural included our Review cover protein based such as collagen, gelatin, silk polysaccharide chitosan, hyaluronic acid, alginate. addition, aliphatic polyesters, super hydrophilic polymers, polyurethanes some most commonly applications. Next, review multifunctional "smart" developed by place an emphasis how flexibility enables production advanced core-shell scaffolds, multilayer surface modified Taken together, clear that emerging technology provides unique opportunity engineering more dressing, management, care products.

Язык: Английский

Процитировано

345

Electrospun polymeric nanofibres as wound dressings: A review DOI
Sónia P. Miguel,

Daniela R. Figueira,

Déborah Simões

и другие.

Colloids and Surfaces B Biointerfaces, Год журнала: 2018, Номер 169, С. 60 - 71

Опубликована: Май 5, 2018

Язык: Английский

Процитировано

329

Electrospinning of natural polymers for the production of nanofibres for wound healing applications DOI
Adrian D. Juncos Bombin, Nicholas Dunne, Helen O. McCarthy

и другие.

Materials Science and Engineering C, Год журнала: 2020, Номер 114, С. 110994 - 110994

Опубликована: Май 5, 2020

Язык: Английский

Процитировано

288

Natural composite dressings based on collagen, gelatin and plant bioactive compounds for wound healing: A review DOI
Alexandra Gaspar‐Pintiliescu, Ana‐Maria Stanciuc, Oana Crăciunescu

и другие.

International Journal of Biological Macromolecules, Год журнала: 2019, Номер 138, С. 854 - 865

Опубликована: Июль 25, 2019

Язык: Английский

Процитировано

284

Current progress in application of polymeric nanofibers to tissue engineering DOI Creative Commons

Sorour Nemati,

Se-jeong Kim,

Young Min Shin

и другие.

Nano Convergence, Год журнала: 2019, Номер 6(1)

Опубликована: Ноя. 8, 2019

Abstract Tissue engineering uses a combination of cell biology, chemistry, and biomaterials to fabricate three dimensional (3D) tissues that mimic the architecture extracellular matrix (ECM) comprising diverse interwoven nanofibrous structure. Among several methods for producing scaffolds, electrospinning has gained intense interest because it can make nanofibers with porous structure high specific surface area. The processing solution parameters considerably affect assembly structural morphology fabricated nanofibers. Electrospun be made from natural or synthetic polymers blending them is straightforward way tune functionality Furthermore, electrospun functionalized various modification strategies. In this review, we highlight latest achievements in fabricating describe ways modify scaffolds promote their functionality. We also summarize application advanced polymeric regeneration human bone, cartilage, vascular tissues, tendons/ligaments.

Язык: Английский

Процитировано

255

Honey loaded alginate/PVA nanofibrous membrane as potential bioactive wound dressing DOI
Yadong Tang, Xingzi Lan,

Chengfeng Liang

и другие.

Carbohydrate Polymers, Год журнала: 2019, Номер 219, С. 113 - 120

Опубликована: Май 8, 2019

Язык: Английский

Процитировано

252