Angewandte Chemie International Edition,
Год журнала:
2017,
Номер
57(5), С. 1152 - 1160
Опубликована: Окт. 12, 2017
Abstract
The
development
of
highly
selective
procedures
is
one
the
core
goals
in
organic
chemistry.
Among
known
transformations,
carbonylation
reactions
present
an
ideal
choice
for
preparation
carbonyl‐containing
compounds.
In
this
review,
recent
achievements
on
control
selectivity
have
been
summarized.
effects
ligands,
solvents,
and
bases
are
discussed.
Angewandte Chemie International Edition,
Год журнала:
2018,
Номер
58(32), С. 10820 - 10843
Опубликована: Ноя. 29, 2018
Directing
group
assisted
ortho-C-H
activation
has
been
known
for
the
last
few
decades.
In
contrast,
extending
same
approach
to
achieve
of
distal
meta-
and
para-C-H
bonds
in
aromatic
molecules
remained
elusive
a
long
time.
The
main
challenge
is
conception
macrocyclic
transition
state,
which
needed
anchor
metal
catalyst
close
target
bond.
Judicious
modification
chain
length,
tether
linkage,
nature
catalyst-coordinating
donor
atom
led
number
successful
studies
years.
This
Review
compiles
significant
achievements
made
this
field
both
para-selectivity
using
covalently
attached
directing
groups,
are
systematically
classified
on
basis
their
mode
covalent
attachment
substrate
as
well
chemical
nature.
aims
create
more
heuristic
recognizing
suitability
groups
use
future
organic
transformations.
ACS Catalysis,
Год журнала:
2018,
Номер
8(6), С. 5085 - 5144
Опубликована: Апрель 13, 2018
Carbon–carbon/carbon–heteroatom
bond
formation
via
oxidative
transformations
is
a
heavily
explored
topic
at
the
frontier
of
chemistry.
Potassium
persulfate
(K2S2O8)
has
emerged
as
cost-effective,
suitable
inorganic
oxidant
for
wide
array
transformations,
ranging
from
laboratory
experiments
to
industrial
processes.
The
current
review
provides
comprehensive
coverage
aided
with
K2S2O8
in
presence
or
absence
transition-metal
catalyst,
critical
assessment
results,
and
underlying
mechanisms.
Organic
chemists
may
find
this
be
useful
guide
expedient
synthesis
new
chemical
entities,
formulate
mechanistic
manifolds
involving
sulfate
radical
anion,
design
novel
transformations.
A
detailed
understanding
unsolved
mechanisms
could
further
enrich
field.
Angewandte Chemie International Edition,
Год журнала:
2017,
Номер
57(9), С. 2296 - 2306
Опубликована: Дек. 5, 2017
Abstract
C−H
activation
reactions
with
high
catalyst
turnover
numbers
are
still
very
rare
in
the
literature
and
10
mol
%
is
a
common
loading
this
field.
We
offer
representative
overview
of
efficient
catalysis
to
highlight
neglected
aspect
development
inspire
future
effort
towards
more
activation.
Examples
ranging
from
palladium
catalysis,
Cp*Rh
III
‐
Cp*Co
‐catalysis,
borylation
silylation
methane
presented.
In
these
reactions,
up
tens
thousands
turnovers
have
been
observed.
Chemical Society Reviews,
Год журнала:
2017,
Номер
47(1), С. 149 - 171
Опубликована: Окт. 26, 2017
The
elaboration
of
simple
arenes
in
order
to
access
more
complex
substitution
patterns
is
a
crucial
endeavor
for
synthetic
chemists,
given
the
central
role
that
aromatic
rings
play
all
manner
important
molecules.
Classical
methods
are
now
routinely
used
alongside
stoichiometric
organometallic
approaches
and,
most
recently,
transition
metal
catalysis
range
methodologies
available
elaborate
arene
C-H
bonds.
Regioselectivity
an
consideration
when
selecting
method
those
available,
it
arguably
target
meta
position
fewest
number.
rapid
development
metal-catalysed
bond
functionalisation
over
last
few
decades
has
opened
new
possibilities
meta-selective
through
diverse
reactivity
metals
and
their
compatibility
with
wide
directing
groups.
pace
discovery
such
processes
grown
rapidly
five
years
particular
purpose
this
review
examine
these
but
doing
so
place
focus
on
other
than
palladium,
specific
contributions
which
have
been
very
recently
reviewed
elsewhere.
It
hoped
will
serve
highlight
reader
breadth
current
strategies
mechanisms
tackle
challenge,
may
inspire
further
progress
field.
Organic Letters,
Год журнала:
2017,
Номер
19(19), С. 5256 - 5259
Опубликована: Сен. 13, 2017
Sulfoxonium
ylides
act
as
an
efficient
carbene
precursor
in
rhodium(III)-catalyzed
C-H
acylmethlyation
of
a
variety
arenes
assisted
by
different
chelating
groups,
and
both
aryl-
alkyl-substituted
β-carbonyl
sulfoxonium
are
applicable.
The
system
proceeded
under
redox-neutral
conditions
with
broad
scope,
high
efficiency,
functional
group
tolerance.
Angewandte Chemie International Edition,
Год журнала:
2018,
Номер
58(18), С. 5832 - 5844
Опубликована: Дек. 27, 2018
Abstract
The
Catellani
reaction
is
known
as
a
powerful
strategy
for
the
expeditious
synthesis
of
highly
substituted
arenes
and
benzo‐fused
rings,
which
are
usually
difficult
to
access
through
traditional
cross‐coupling
strategies.
It
utilizes
synergistic
interplay
palladium
norbornene
catalysis
facilitate
sequential
ortho
C−H
functionalization
ipso
termination
aryl
halides
in
single
operation.
In
classical
Catellani‐type
reactions,
mainly
used
substrates,
Pd
0
catalyst
required
initiate
reaction.
Nevertheless,
recent
advances
showcase
that
reactions
can
also
be
initiated
by
II
with
different
starting
materials
instead
via
mechanisms
under
conditions.
This
emerging
concept
/norbornene
cooperative
has
significantly
advanced
thus
enabling
future
developments
this
field.
Minireview,
‐initiated
their
application
bioactive
molecules
summarized.
Organic & Biomolecular Chemistry,
Год журнала:
2019,
Номер
17(24), С. 5863 - 5881
Опубликована: Янв. 1, 2019
The
direct
C3-functionalization
of
quinoxalin-2(1H)-ones
via
C–H
bond
activation
has
recently
attracted
considerable
attention,
due
to
their
diverse
biological
activities
and
chemical
properties.
Journal of the American Chemical Society,
Год журнала:
2019,
Номер
141(19), С. 7972 - 7979
Опубликована: Апрель 21, 2019
We
report
herein
the
iridium-catalyzed
meta-selective
C–H
borylation
of
benzamides
by
using
a
newly
designed
2,2′-bipyridine
(bpy)
ligand
bearing
an
alkylaluminum
biphenoxide
moiety.
also
demonstrate
C3-selective
pyridine
with
1,10-phenanthroline
(Phen)
alkylborane
It
is
proposed
that
Lewis
acid–base
interaction
between
acid
moiety
and
aminocarbonyl
group
or
sp2-hybridized
nitrogen
atom
accelerates
reaction
controls
site-selectivity.