ACS Applied Polymer Materials,
Год журнала:
2023,
Номер
5(8), С. 6625 - 6632
Опубликована: Авг. 1, 2023
Sunscreens
can
help
protect
the
skin
from
solar
ultraviolet
(UV)
radiation,
which
is
harmful
to
human
health.
However,
traditional
sunscreens
penetrate
skin,
raising
concerns
about
their
safety.
Therefore,
fabrication
of
a
sunscreen
with
biocompatible,
UV-shielding,
and
antioxidant
properties
pertinent.
Herein,
simple
method
involving
self-polymerization
dopamine
polydopamine
(PDA)
was
proposed
for
surface
modification
poly(vinyl
alcohol)
(PVA)
cellulose
nanocrystals
(CNCs)
fabricate
nanocrystal/polydopamine/poly(vinyl
(CNC/PDA/PVA)
hydrogels.
Compression
tests
revealed
that
CNC/PDA/PVA
hydrogel
had
compression
strength
5.0
MPa.
After
UV
exposure
2400
h,
PVA
decreased
markedly
3.5
1.5
MPa,
whereas
slightly
4.8
Mouse
embryonic
fibroblast
(NIH-3T3)
cell
experiments
showed
exhibited
excellent
biocompatibility.
A
decrease
in
residual
1,1-diphenyl-2-picrylhydrazyl
(DPPH)
content
100.0%
4.0%
implied
strong
capacity
hydrogel.
Notably,
UV–vis
spectroscopy
analysis
vivo
mouse
demonstrated
blocked
approximately
99.0%
light
prevented
UV-induced
tissue
injury,
respectively.
These
results
indicate
potential
applications
prepared
as
absorber
next-generation
antioxidative
UV-shielding
materials.
Journal of Nanobiotechnology,
Год журнала:
2023,
Номер
21(1)
Опубликована: Сен. 30, 2023
Excessive
and
prolonged
ultraviolet
radiation
(UVR)
exposure
causes
photodamage,
photoaging,
photocarcinogenesis
in
human
skin.
Therefore,
safe
effective
sun
protection
is
one
of
the
most
fundamental
requirements.
Living
organisms
tend
to
evolve
various
natural
photoprotective
mechanisms
avoid
photodamage.
Among
them,
melanin
main
functional
component
system
Polydopamine
(PDA)
synthesized
as
a
mimic
melanin,
however,
its
efficiency
mechanism
protecting
against
skin
damage
photoaging
remain
unclear.
In
this
study,
novel
sunscreen
products
based
on
melanin-inspired
PDA
nanoparticles
(NPs)
are
rationally
designed
prepared.
We
validate
that
NPs
exhibits
superior
effects
photoprotection,
which
achieved
by
obstruction
epidermal
hyperplasia,
barrier,
resolution
inflammation.
addition,
we
find
efficiently
intake
keratinocytes,
exhibiting
robust
ROS
scavenging
DNA
ability
with
minimal
cytotoxicity.
Intriguingly,
has
an
influence
maintaining
homeostasis
dermis,
displaying
anti-photoaging
property.
Taken
together,
biocompatibility
full
properties
display
performance
those
commercial
sunscreen.
This
work
provides
new
insights
into
development
melanin-mimicking
material
for
sunscreens.
The Journal of Physical Chemistry A,
Год журнала:
2020,
Номер
124(15), С. 2919 - 2930
Опубликована: Март 25, 2020
Avobenzone
(AB)
is
a
widely
used
UVA
filter
known
to
undergo
irreversible
photodegradation.
Here,
we
investigate
the
detailed
pathways
by
which
AB
photodegrades
applying
UV
laser-interfaced
mass
spectrometry
protonated
ions.
Gas-phase
infrared
multiple-photon
dissociation
(IRMPD)
spectra
obtained
with
free
electron
laser
for
experiments,
FELIX,
(600-1800
cm-1)
are
also
presented
confirm
geometric
structures.
The
gas-phase
absorption
spectrum
(2.5-5
eV)
of
contains
bands
that
correspond
selective
excitation
either
enol
or
diketo
forms,
allowing
us
probe
resulting,
tautomer-dependent
photochemistry.
Numerous
photofragments
(i.e.,
photodegradants)
directly
identified
first
time,
m/z
135
and
161
dominating,
146
177
appearing
prominently.
Analysis
production
these
reveals
strong
keto
photoisomerism
occurring,
protonation
significantly
disrupts
stability
(UVA
active)
tautomer.
Close
comparison
fragment
ion
yields
TD-DFT-calculated
give
information
on
location
identity
dissociative
excited
state
surfaces,
thus
provide
new
insight
into
photodegradation
avobenzone,
photoisomerization
wider
class
β-diketone
containing
molecules.
ACS Applied Polymer Materials,
Год журнала:
2023,
Номер
5(8), С. 6625 - 6632
Опубликована: Авг. 1, 2023
Sunscreens
can
help
protect
the
skin
from
solar
ultraviolet
(UV)
radiation,
which
is
harmful
to
human
health.
However,
traditional
sunscreens
penetrate
skin,
raising
concerns
about
their
safety.
Therefore,
fabrication
of
a
sunscreen
with
biocompatible,
UV-shielding,
and
antioxidant
properties
pertinent.
Herein,
simple
method
involving
self-polymerization
dopamine
polydopamine
(PDA)
was
proposed
for
surface
modification
poly(vinyl
alcohol)
(PVA)
cellulose
nanocrystals
(CNCs)
fabricate
nanocrystal/polydopamine/poly(vinyl
(CNC/PDA/PVA)
hydrogels.
Compression
tests
revealed
that
CNC/PDA/PVA
hydrogel
had
compression
strength
5.0
MPa.
After
UV
exposure
2400
h,
PVA
decreased
markedly
3.5
1.5
MPa,
whereas
slightly
4.8
Mouse
embryonic
fibroblast
(NIH-3T3)
cell
experiments
showed
exhibited
excellent
biocompatibility.
A
decrease
in
residual
1,1-diphenyl-2-picrylhydrazyl
(DPPH)
content
100.0%
4.0%
implied
strong
capacity
hydrogel.
Notably,
UV–vis
spectroscopy
analysis
vivo
mouse
demonstrated
blocked
approximately
99.0%
light
prevented
UV-induced
tissue
injury,
respectively.
These
results
indicate
potential
applications
prepared
as
absorber
next-generation
antioxidative
UV-shielding
materials.
