Iodine-mediated synthesis of indolyl-1,3,4-thiadiazole amine derivatives and their DFT analysis

RSC Advances, Год журнала: 2025, Номер 15(19), С. 15108 - 15115

Опубликована: Янв. 1, 2025

This study reports a metal-free, three-component synthesis of substituted indolyl-1,3,4-thiadiazole amines, their functionalization into diverse N-heterocycles, and theoretical evaluation via DFT analysis.

Язык: Английский

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Iodine-catalyzed chemoselective dehydrogenation and aromatization of tetrahydro-β-carbolines: A short synthesis of Kumujian-C, Eudistomin-U, Norharmane, Harmane Harmalan and Isoeudistomine-M

Tetrahedron Letters, Год журнала: 2018, Номер 59(25), С. 2387 - 2392

Опубликована: Апрель 19, 2018

Язык: Английский

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One‐Pot, Two‐Step Metal and Acid‐Free Synthesis of Trisubstituted Imidazole Derivatives via Oxidation of Internal Alkynes Using an Iodine/DMSO System

European Journal of Organic Chemistry, Год журнала: 2018, Номер 2019(5), С. 1107 - 1113

Опубликована: Дек. 27, 2018

A one‐pot, two‐step, simple, efficient and eco‐friendly oxidation of internal alkynes as a key step towards the synthesis 2,4,5‐trisubstituted imidazoles, using an inexpensive I 2 /DMSO system, has been reported. This metal acid‐free proceeded smoothly to furnish variety synthetically useful trisubstituted imidazoles in moderate excellent yields. In effort demonstrate potential future applications this double study was undertaken desired obtained good

Язык: Английский

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Iodine-catalyzed synthesis of N,N′-diaryl-o-phenylenediamines from cyclohexanones and anilines using DMSO and O₂ as oxidants

Chemical Communications, Год журнала: 2018, Номер 54(69), С. 9679 - 9682

Опубликована: Янв. 1, 2018

A novel I2-catalyzed cross-dehydrogenative aromatization of cyclohexanones and anilines to synthesize N,N'-diaryl-o-phenylenediamines has been unprecedentedly developed with dimethyl sulfoxide oxygen employed as mild terminal oxidants. To prove the rationality two separate dehydration steps proposed mechanism, a resulting cyclohexenones diarylamines also reported.

Язык: Английский

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Iodine/DMSO promoted oxidation of benzylic Csp3–H bonds to diketones – A mechanistic investigation

Tetrahedron, Год журнала: 2019, Номер 75(43), С. 130617 - 130617

Опубликована: Сен. 19, 2019

Язык: Английский

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