iScience,
Год журнала:
2024,
Номер
27(3), С. 109223 - 109223
Опубликована: Фев. 15, 2024
SummaryIn
recent
years,
significant
advancements
have
been
made
in
the
synthesis
and
application
of
1,3-dienes.
This
specific
structural
motif
has
garnered
attention
from
researchers
materials
science
biology
due
to
its
unique
aggregation-induced
emission
(AIE)
properties
extensive
conjugation
systems.
The
luminescent
characteristics
these
compounds
are
notably
influenced
by
geometry
two
double
bonds.
Therefore,
it
is
essential
consolidate
stereoselective
synthetic
strategies
for
comprehensive
review
seeks
elucidate
diverse
techniques
employed
attain
stereo-control
1,3-diene-based
AIE
luminogens
(AIEgens).
Particular
emphasis
placed
on
comprehending
determinants
stereoselectivity
exploring
array
substrates
amenable
methods.
Furthermore,
underscores
exhibited
their
utility
organic
light-emitting
diodes
(OLEDs),
stimuli-responsive
materials,
sensors,
bioimaging,
photodynamic
therapy
(PDT).Graphical
abstract
ACS Catalysis,
Год журнала:
2021,
Номер
11(6), С. 3443 - 3454
Опубликована: Март 3, 2021
Although
breakthroughs
in
the
N-heterocyclic
carbene
(NHC)-catalyzed
inert
C–C
bond
activation
strategy
have
been
achieved,
understanding
role
of
catalyst
as
well
origin
its
chemo-
and
stereoselectivities
is
still
one
most
challenging
questions
field
organocatalysis.
Herein,
we
propose
an
NHC
NHC·H+
cooperative
catalytic
model
for
these
kinds
reactions
perform
density
functional
theory
calculations
case
NHC-catalyzed
[4
+
2]
annulation
reaction
conjugated
dienal
α-aryl
ketone.
The
calculated
results
indicate
that
organocatalyst
either
works
a
Lewis
base
to
prevent
bad
frontier
molecular
orbital
overlap
mode,
promoting
[2
cycloaddition,
or
noncovalent
provide
hydrogen
bonding
network
facilitate
release
CO2.
latter
remarkably
different
from
well-known
base.
In
addition,
devised
atomic
electrophilicity
index
correctly
predict
site
stereoselective
formation
involved
cycloaddition.
Further
analysis
show
bonds
significantly
contribute
favorable
pathway,
which
was
associated
with
axial
chirality
main
final
product
experiment.
obtained
insights
should
be
valuable
prediction
rational
design
organocatalytic
activations
special
chemoselectivity
high
stereoselectivity.
ACS Catalysis,
Год журнала:
2021,
Номер
11(7), С. 4263 - 4270
Опубликована: Март 19, 2021
Free
radical
cyclization
has
emerged
as
one
of
the
most
important
reaction
types,
which
is
widely
used
in
natural
product
synthesis,
pharmaceutical
chemistry,
and
materials
science.
This
report
described
combination
ruthenium-catalyzed
meta-selective
C–H
functionalization
for
synthesis
arylpyrrolidone
derivatives.
method
exhibited
highly
meta-site
selectivity
primary,
secondary,
tertiary
alkyl
radicals
formed
by
intramolecular
addition.
A
wide
spectrum
directing
groups
bearing
diversified
N-heterocycles
performed
well,
including
biologically
active
molecules.
Density
functional
theory
calculations
provided
a
theoretical
basis
high
meta-selectivity
favored
pathway
an
cyclization.
Angewandte Chemie International Edition,
Год журнала:
2023,
Номер
62(29)
Опубликована: Май 17, 2023
Sulfondiimines
are
diaza-analogues
of
sulfones
with
a
chiral
sulfur
center.
Compared
to
and
sulfoximines,
their
synthesis
transformations
have
so
far
been
studied
lesser
extent.
Here,
we
report
the
enantioselective
1,2-benzothiazine
1-imines,
i.e.,
cyclic
sulfondiimine
derivatives
from
sulfondiimines
sulfoxonium
ylides
via
C-H
alkylation/cyclization
reactions.
The
combination
[Ru(p-cymene)Cl2
]2
newly
developed
spiro
carboxylic
acid
is
key
achieving
high
enantioselectivity.
iScience,
Год журнала:
2024,
Номер
27(3), С. 109223 - 109223
Опубликована: Фев. 15, 2024
SummaryIn
recent
years,
significant
advancements
have
been
made
in
the
synthesis
and
application
of
1,3-dienes.
This
specific
structural
motif
has
garnered
attention
from
researchers
materials
science
biology
due
to
its
unique
aggregation-induced
emission
(AIE)
properties
extensive
conjugation
systems.
The
luminescent
characteristics
these
compounds
are
notably
influenced
by
geometry
two
double
bonds.
Therefore,
it
is
essential
consolidate
stereoselective
synthetic
strategies
for
comprehensive
review
seeks
elucidate
diverse
techniques
employed
attain
stereo-control
1,3-diene-based
AIE
luminogens
(AIEgens).
Particular
emphasis
placed
on
comprehending
determinants
stereoselectivity
exploring
array
substrates
amenable
methods.
Furthermore,
underscores
exhibited
their
utility
organic
light-emitting
diodes
(OLEDs),
stimuli-responsive
materials,
sensors,
bioimaging,
photodynamic
therapy
(PDT).Graphical
abstract
