Toward a New Era of SERS and TERS at the Nanometer Scale: From Fundamentals to Innovative Applications

Chemical Reviews, Год журнала: 2023, Номер 123(4), С. 1552 - 1634

Опубликована: Фев. 6, 2023

Surface-enhanced Raman scattering (SERS) and tip-enhanced (TERS) have opened a variety of exciting research fields. However, although vast number applications been proposed since the two techniques were first reported, none has applied to real practical use. This calls for an update in recent fundamental application studies SERS TERS. Thus, goals scope this review are report new directions perspectives TERS, mainly from viewpoint combining their mechanism studies. Regarding progress discusses four main topics: (1) nanometer subnanometer plasmonic hotspots SERS; (2) Ångström resolved TERS; (3) chemical mechanisms, i.e., charge-transfer semiconductor-enhanced scattering; (4) creation strong bridge between applications.

Язык: Английский

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Plasmonic silver and gold nanoparticles: shape- and structure-modulated plasmonic functionality for point-of-caring sensing, bio-imaging and medical therapy

Chemical Society Reviews, Год журнала: 2024, Номер 53(6), С. 2932 - 2971

Опубликована: Янв. 1, 2024

Silver and gold nanoparticles have found extensive biomedical applications due to their strong localized surface plasmon resonance (LSPR) intriguing plasmonic properties. This review article focuses on the correlation among particle geometry, properties applications. It discusses how shape size are tailored

Язык: Английский

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Pre-activated nanoparticles with persistent luminescence for deep tumor photodynamic therapy in gallbladder cancer

Nature Communications, Год журнала: 2023, Номер 14(1)

Опубликована: Сен. 14, 2023

Phototherapy of deep tumors still suffers from many obstacles, such as limited near-infrared (NIR) tissue penetration depth and low accumulation efficiency within the target sites. Herein, stimuli-sensitive tumor-targeted photodynamic nanoparticles (STPNs) with persistent luminescence for treatment are reported. Purpurin 18 (Pu18), a porphyrin derivative, is utilized photosensitizer to produce in STPNs, while lanthanide-doped upconversion (UCNPs) exhibit bioimaging properties possess high photostability that can enhance efficacy. STPNs initially stimulated by NIR irradiation before intravenous administration accumulate at tumor site enter cells through HER2 receptor. Due Pu18 afterglow properties, continuously generate ROS inhibit NFκB nuclear translocation, leading cell apoptosis. Moreover, be used diagnostic purposes MRI intraoperative navigation. exceptional antitumor combined advantages UCNPs luminescence, representing promising phototherapeutic strategy tumors.

Язык: Английский

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An overview of Schiff base-based fluorescent turn-on probes: a potential candidate for tracking live cell imaging of biologically active metal ions

Sensors & Diagnostics, Год журнала: 2023, Номер 2(5), С. 988 - 1076

Опубликована: Янв. 1, 2023

This review focused on Schiff base-based fluorescent turn-on probes for detecting biologically important metal ions, paying primary attention to their biological applications.

Язык: Английский

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Biomedical SERS – the current state and future trends

Chemical Society Reviews, Год журнала: 2024, Номер 53(18), С. 8957 - 8979

Опубликована: Янв. 1, 2024

Surface enhanced Raman spectroscopy (SERS) is meeting the requirements in biomedical science being a highly sensitive and specific analytical tool. By employing portable systems combination with customized sample pre-treatment, point-of-care-testing (POCT) becomes feasible. Powerful SERS-active sensing surfaces high stability modification layers if required are available for testing application complex biological matrices such as body fluids, cells or tissues. This review summarizes current state collection pretreatment SERS detection protocols, schemes,

Язык: Английский

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Applications of metal organic frameworks in point of care testing

TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер 172, С. 117596 - 117596

Опубликована: Фев. 8, 2024

Diagnostic devices used in the point-of-care (POC) today play a critical role as tools to provide essential medical surveillance data and ensure that patients receive appropriate timely care. These also allow self-analysis by patient, increasing therapeutic adherence well reducing pressure on clinical structures. The development of new diagnostic tools, therefore, represents significant challenge from technological point view, both terms overcoming current weaknesses costs, accuracy, performance, an analytical view order develop are operator-independent possible. Recent breakthroughs technologies (such cell phone-dependent technologies, paper-based procedures, lab-on-a-chip devices) paving way for next generation testing (POCT). Innovative assay devices, efficient reagent storage techniques, required POCT technologies. Nanomaterials different forms, sizes, compositions, such carbon nanomaterials, quantum dots, gold silver nanoparticles, mesoporous silica metal-organic frameworks (MOFs), have been created characterized recent years. Due their specific physicochemical properties, MOF nanoparticles increasingly being improve performance simplify techniques. MOFs colorimetric or electrochemical carriers plasmonic biosensors be resistant environmental conditions. This review will discuss detailed 2016 2023, addition chemical synthesis characterization methods related uses applications MOF.

Язык: Английский

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Plasmonic nanomaterial-enhanced fluorescence and Raman sensors: Multifunctional platforms and applications

Coordination Chemistry Reviews, Год журнала: 2024, Номер 507, С. 215768 - 215768

Опубликована: Март 5, 2024

Язык: Английский

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Raman spectroscopy for food quality assurance and safety monitoring: a review

Current Opinion in Food Science, Год журнала: 2022, Номер 47, С. 100910 - 100910

Опубликована: Авг. 4, 2022

Язык: Английский

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Emerging SERS biosensors for the analysis of cells and extracellular vesicles

Nanoscale, Год журнала: 2022, Номер 14(41), С. 15242 - 15268

Опубликована: Янв. 1, 2022

Cells and their derived extracellular vesicles (EVs) or exosomes contain unique molecular signatures that could be used as biomarkers for the detection of severe diseases such cancer, well monitoring treatment response. Revealing these requires developing non-invasive ultrasensitive tools to enable single molecule/cell-level using a small volume sample with low signal-to-noise ratio background multiplex capability. Surface-enhanced Raman scattering (SERS) can address current limitations in studying cells EVs through two main mechanisms: plasmon-enhanced electric field (the so-called electromagnetic mechanism (EM)), chemical (CM). In this review, we first highlight SERS mechanisms then discuss nanomaterials have been develop biosensors based on each aforementioned combination order take advantage synergic effect between enhancement enhancement. Then, review recent advances designing label-aided label-free both colloidal planar systems investigate surface cancer EVs. Finally, perspectives emerging future biomedical applications. We believe article will thus appeal researchers nanobiotechnology including material sciences, biosensors, fields.

Язык: Английский

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Transition Metal Nitrides Are Heating Up the Field of Plasmonics

Chemistry of Materials, Год журнала: 2022, Номер 34(10), С. 4249 - 4258

Опубликована: Май 2, 2022

Metal nitride nanostructures have been predicted to exhibit plasmonic responses in the UV IR region, which can enable their potential use as low-cost, chemically, and thermally stable materials several applications. In case of photothermal applications, nitrides shown, both numerically experimentally, perform better than noble metals. Additionally superior thermal stability metal offers compatibility with high temperature device fabrication techniques. The plasmon frequency for transition be tuned from region by varying type metal/nitrogen ratio. Recently, studies focused on developing applying free-standing nanostructures. Most investigations TiN, but late focus has shifting investigate other nanostructured such ZrN HfN. This Perspective will highlight recent key findings synthesis nitrides; associated properties; application therapy, solar-driven water evaporation, chemical reactions. An outlook current knowledge gaps challenges future directions further this field is also presented.

Язык: Английский

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