The Journal of Organic Chemistry,
Год журнала:
2019,
Номер
84(20), С. 13092 - 13103
Опубликована: Сен. 24, 2019
This
manuscript
details
the
development
of
nickel-catalyzed
arylation
oxazoles
and
benzoxazoles
with
aryl
halides.
A
series
aryl,
heteroaryl,
druglike
electrophiles
relevant
to
pharmaceutical
applications
were
surveyed.
The
desired
arylated
products
obtained
in
synthetically
useful
yields
using
electronically
structurally
varied
use
microscale
high-throughput
experimentation
was
essential
for
both
rapid
identification
optimal
reaction
parameters
investigation
halide
scope.
Chemical Society Reviews,
Год журнала:
2021,
Номер
50(6), С. 4162 - 4184
Опубликована: Янв. 1, 2021
This
review
provides
a
comprehensive
summary
of
recent
advances
in
nickel-catalyzed
reactions
employing
tertiary
alkyl
electrophiles
for
the
construction
quaternary
carbon
centers.
ACS Catalysis,
Год журнала:
2022,
Номер
12(5), С. 3013 - 3032
Опубликована: Фев. 18, 2022
Sulfones
are
common,
readily
available
reagents
that
have
recently
attracted
attention
as
versatile
for
cross-coupling
reactions.
This
Review
summarizes
advances
in
desulfonylative
transformations
of
sulfones
affected
by
molecular
catalysis,
including
transition-metal
catalysts,
photocatalysts,
and
organocatalysts.
In
addition
to
catalyst
choice,
the
design
sulfonyl
group
is
a
critical
factor
control
reactivity.
The
concepts
presented
herein
will
provide
new
strategies
construct
diverse
molecules
with
high
efficiency
modularity.
Chemical Science,
Год журнала:
2023,
Номер
14(25), С. 6915 - 6929
Опубликована: Янв. 1, 2023
Nickel
K-
and
L
2,3
-edge
X-ray
absorption
spectra
(XAS)
are
discussed
for
coordinated
nickel
centers
spanning
formal
oxidation
states
from
II
to
IV.
The
ensuing
analysis
indicates
that
a
physical
“+4”
state
is
untenable
Ni.
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
146(13), С. 9172 - 9180
Опубликована: Март 21, 2024
The
catalytic
asymmetric
construction
of
axially
chiral
C–N
atropisomers
remains
a
formidable
challenge
due
to
their
low
rotational
barriers
and
is
largely
reliant
on
toxic,
cost-intensive,
precious
metal
catalysts.
In
sharp
contrast,
we
herein
describe
the
first
nickel-catalyzed
atroposelective
C–H
alkylation
for
compounds
with
aid
heteroatom-substituted
secondary
phosphine
oxide
(HASPO)-ligated
Ni–Al
bimetallic
catalyst.
A
wide
range
alkenes,
including
terminal
internal
were
well
compatible
reaction,
providing
variety
benzimidazole
derivatives
in
high
yields
enantioselectivities
(up
97:3
e.r.).
key
success
was
identification
novel
HASPOs
as
highly
effective
preligands.
Mechanistic
studies
revealed
catalyst
mode
action,
in-depth
data
science
analysis
elucidated
features
responsible
preligands
controlling
enantioselectivity.
Advanced Synthesis & Catalysis,
Год журнала:
2019,
Номер
361(22), С. 5170 - 5175
Опубликована: Сен. 25, 2019
Abstract
Photoredox‐based
C−H
bond
functionalization
constitutes
one
of
the
most
powerful
and
atom‐economical
approaches
to
organic
syntheses.
During
this
type
reaction,
single
electron
transfer
takes
place
between
photocatalyst
(
PC
)
redox‐
active
substrates.
Electrosynthesis
also
involves
substrates
electrodes.
In
paper,
we
focus
upon
electrochemical
cross‐coupling
C(
sp
2
)−H
with
aryldiazonium
salts
have
developed
an
efficient
approach
Minisci‐type
arylation
reaction.
The
constant
current
paired
electrosynthesis
proceeds
in
a
simple
undivided
cell
without
external
supporting
electrolyte,
features
wide
range
is
easy
scale‐up.
These
results
demonstrate
that
photoredox‐based
can
proceed
successfully
under
electrolysis
conditions,
thereby
contributing
understanding
parallels
photosynthesis
electrosynthesis.
magnified
image
ACS Catalysis,
Год журнала:
2020,
Номер
10(8), С. 4780 - 4785
Опубликована: Март 26, 2020
This
work
reports
the
enantioselective
formal
transfer
of
a
carbamoyl
iodide
across
1,1-disubstituted
styrene
using
Ni-catalysis.
Employing
an
air-stable
Ni(II)
precatalyst
and
commercially
available
chiral
ligand
((S)-tBuPHOX),
enantioenriched
3,3-disubstituted
iodooxindoles
were
obtained
in
up
to
90%
yield
97:3
e.r.
methodology
was
applied
total
synthesis
(−)-esermethole
(−)-phenserine.
Advanced Synthesis & Catalysis,
Год журнала:
2020,
Номер
362(8), С. 1602 - 1650
Опубликована: Янв. 29, 2020
Abstract
Manganese‐catalysed
reactions
have
attracted
great
attention
recently
due
to
the
high
relative
abundance
and
cheap
eco‐friendly
behaviour.
Applications
of
manganese
catalysis
in
cross‐dehydrogenative
coupling
are
among
hottest
areas
since
90%
contributions
very
recent.
Dehydrogenation
alcohols
using
Mn‐pincer
systems
is
highly
explored
nowadays
for
cross‐coupling
synthesise
a
variety
products
Mn‐catalysed
C−H
activation,
radical
applied
dehydrogenative
couplings
various
synthons.
This
review
focuses
on
synthesis
synthetically
as
well
biologically
important
motifs
such
carbonyl
compounds,
olefins,
nitrogen
heterocycles,
amines,
imines,
etc.
manganese‐catalysed
reactions.
magnified
image
Dalton Transactions,
Год журнала:
2019,
Номер
48(33), С. 12365 - 12381
Опубликована: Янв. 1, 2019
In
this
Perspective,
we
will
highlight
selected
examples
of
transition
metal
complexes
with
low
coordination
numbers
whose
high
reactivity
has
been
exploited
in
catalysis
and
the
activation
small
molecules
featuring
strong
bonds
(N2,
CO2,
CO).
