CrystEngComm,
Год журнала:
2021,
Номер
23(22), С. 3995 - 4004
Опубликована: Янв. 1, 2021
Methanol
and
methyl
acetate
molecules
played
different
roles
in
the
formation
of
SM–M
amoxicillin
sodium
heterosolvate.
A
two-step
desolvation
mechanism
novel
heterosolvates
was
proposed.
Studying
basic
parameters
of
heat
and
thermodynamics
can
explore
new
insights
into
science.
Gaseous
solid
atoms
under
transitional
behaviors
remarkable
advances
in
chemical
physical
sciences.
An
anomaly
the
first
law
be
recognized
explicitly
when
are
study.
By
gaining
transition
energy,
gaseous
undertake
a
state.
Hence,
work
performs
by
atoms.
Symbolically,
plus
sign
requires
for
it.
But
transitions
occur
because
absorbing
energy.
So,
performance
is
minus
sign.
A
different
force
exerts
on
electron
atom
atom,
where
energy
changes
potential
electron,
thus
controlling
orientation
force.
resolves
changing
equations
internal
On
attaining
mid-states,
introduce
cooling
effects
elastically
driven
electronic
states.
state
between
re-crystallization
liquid
states
consider
mid-state.
In
generating
or
heating
an
executes
dynamics
remaining
within
occupied
knot.
Thus,
constantly
cause
disorder
irreversible
cycles.
The
study
presents
understanding
thermodynamics,
cold
entropy,
condensed
matter
science
at
atomic
levels
insight.
Studying
basic
parameters
of
heat
and
thermodynamics
can
explore
new
insights
into
science.
Gaseous
solid
atoms
under
transitional
behaviors
remarkable
advances
in
chemical
physical
sciences.
An
anomaly
the
first
law
be
recognized
explicitly
when
are
study.
By
gaining
transition
energy,
gaseous
undertake
a
state.
Hence,
work
performed
by
atoms.
Symbolically,
plus
sign
is
needed
to
use
for
it.
However,
transitions
occur
because
absorbing
energy.
So,
performance
minus
sign.
A
force
exerted
on
atom
electron
different
from
electron,
where
energy
changes
potential
that
thus
controlling
orientation
force.
resolves
changing
equations
internal
On
attaining
mid-states,
introduce
cooling
effects
elastically
driven
electronic
states.
state
between
re-crystallization
liquid
states
considered
mid-state.
In
generating
or
heating
an
executes
dynamics
remaining
within
occupied
knot.
Thus,
constantly
cause
disorder
irreversible
cycles.
The
study
presents
understanding
thermodynamics,
cold
entropy,
condensed
matter
science
at
atomic
levels
insight.
Crystal Growth & Design,
Год журнала:
2024,
Номер
24(12), С. 5014 - 5026
Опубликована: Июнь 4, 2024
Detailed
crystallographic
and
computational
analysis
of
solvates
dasatinib
(DAS),
an
inhibitor
multiple
tyrosine
kinases,
was
performed
by
confirming
the
high
structural
similarity
most
DAS
crystal
structures
identifying
differences
in
molecular
conformation,
hydrogen
bonding,
packing.
The
14
new
are
presented,
allowing
23
one
nonsolvated
phase.
conformation
revealed
that
adopts
three
slightly
different
conformations,
even
though
indicated
existence
alternative
energetically
competitive
conformations.
In
almost
all
structures,
molecules
form
identical
hydrogen-bonded
layers.
lack
variation
is
believed
to
be
result
limited
ways
for
efficient
packing
large
sized
specifically
shaped
molecules.
analysis,
however,
similar
but
somewhat
these
layers
packed,
resulting
classification
structure
groups
I,
II,
III.
arrangements
bonds
formed
O1–H
space
available
solvent,
but,
interestingly,
this
not
linked
with
exact
or
solvent
functionality,
properties,
bonding
Acta Crystallographica Section C Structural Chemistry,
Год журнала:
2022,
Номер
78(4), С. 240 - 249
Опубликована: Март 25, 2022
Seven
solvates
of
the
angiotensin
II
receptor
blocker
agent
olmesartan
(C
24
H
26
N
6
O
3
),
namely,
methanol
·CH
4
O),
ethanol
·C
2
isopropanol
8
isobutanol
10
2-ethoxyethanol
chloroform
·CHCl
)
and
acetonitrile
N)
solvates,
were
successfully
obtained.
The
crystal
structures
determined
using
single-crystal
X-ray
diffraction
technique
structural
features
are
described,
each
solvate
containing
one
molecule
solvent
in
asymmetric
unit.
samples
also
analyzed
by
powder
diffraction.
Total
lattice
energies
binding
between
molecules
evaluated,
which
can
be
partitioned
into
electrostatic,
polarization,
dispersion
repulsion
components.
Hirshfeld
fingerprint
plot
analysis
was
performed
to
highlight
intermolecular
contacts.
Hydrogen
bonding
supramolecular
arrangements
comparatively
studied
for
seven
solvates.
CrystEngComm,
Год журнала:
2021,
Номер
23(22), С. 3995 - 4004
Опубликована: Янв. 1, 2021
Methanol
and
methyl
acetate
molecules
played
different
roles
in
the
formation
of
SM–M
amoxicillin
sodium
heterosolvate.
A
two-step
desolvation
mechanism
novel
heterosolvates
was
proposed.