Phosphine Ligand Development for Homogeneous Asymmetric Hydrogenation DOI
Graham E. Dobereiner, Xumu Zhang, Heng Wang

и другие.

Elsevier eBooks, Год журнала: 2021, Номер unknown, С. 1 - 31

Опубликована: Дек. 28, 2021

Язык: Английский

Asymmetric hydrogenation of unfunctionalized olefins or with poorly coordinative groups DOI
Òscar Pàmies, Jia Zheng, Jorge Faiges

и другие.

Advances in catalysis, Год журнала: 2021, Номер unknown, С. 135 - 203

Опубликована: Янв. 1, 2021

Язык: Английский

Процитировано

6
Synthesis of spiro[4.4]thiadiazole derivatives via double 1,3-dipolar cycloaddition of hydrazonyl chlorides with carbon disulfide DOI Creative Commons
Kai‐Kai Wang,

LI Yan-li,

Dongguang Guo

и другие.

RSC Advances, Год журнала: 2021, Номер 11(30), С. 18404 - 18407

Опубликована: Янв. 1, 2021

An operationally simple and convenient synthesis method toward a series of diverse spiro[4.4]thiadiazole derivatives via double [3 + 2] 1,3-dipolar cycloaddition nitrilimines generated in situ from hydrazonyl chlorides with carbon disulfide has been achieved under mild reaction conditions.

Язык: Английский

Процитировано

4
Synthesis of Chiral Tetrahydro-3-benzazepine Motifs by Iridium-Catalyzed Asymmetric Hydrogenation of Cyclic Ene-carbamates DOI Creative Commons
Bram B. C. Peters, Pher G. Andersson, Somsak Ruchirawat

и другие.

Organic Letters, Год журнала: 2022, Номер 24(10), С. 1969 - 1973

Опубликована: Март 3, 2022

A highly efficient N,P-ligated iridium complex is presented for the simple preparation of chiral tetrahydro-3-benzazepine motifs by catalytic asymmetric hydrogenation. Substrates bearing both 1-aryl and 1-alkyl substituents were smoothly converted to corresponding hydrogenated product with excellent enantioselectivity (91–99% ee) in isolated yield (92–99%). The synthetic value this transformation was demonstrated a gram-scale hydrogenation application syntheses trepipam fenoldopam.

Язык: Английский

Процитировано

3
Five-membered ring systems with O and N atoms DOI
Franca M. Cordero, Luisa Lascialfari, Fabrizio Machetti

и другие.

Progress in heterocyclic chemistry, Год журнала: 2023, Номер unknown, С. 355 - 386

Опубликована: Янв. 1, 2023

Язык: Английский

Процитировано

1
Reduction: Hydrogenation and Transfer Hydrogenation of C=C DOI
Masaki Tsukamoto, Kin‐ichi Oyama

Elsevier eBooks, Год журнала: 2023, Номер unknown, С. 266 - 287

Опубликована: Апрель 13, 2023

Язык: Английский

Процитировано

1
Photochemical Deracemization of 3‐Substituted Oxindoles DOI Creative Commons
Johannes Großkopf, Alexandra A. Heidecker, Thorsten Bach

и другие.

Angewandte Chemie, Год журнала: 2023, Номер 135(30)

Опубликована: Май 22, 2023

Abstract Racemic 3‐substituted oxindoles were successfully converted into enantiomerically pure or enriched material (up to 99 % ee ) upon irradiation at λ =366 nm in the presence of a chiral benzophenone catalyst (10 mol %). The photochemical deracemization process allows predictable editing stereogenic center carbon atom C3. Light energy compensates for associated loss entropy and enables decoupling potentially reversible reactions, i.e. hydrogen transfer (photochemical) from (thermal) carbonyl group catalyst. major enantiomer is continuously several catalytic cycles. obtained shown be valuable intermediates further transformations, which proceeded with complete retention center.

Язык: Английский

Процитировано

1
Iridium-Catalyzed asymmetric reduction of α,β-Unsaturated nitriles with water DOI Creative Commons

Qinli Lu,

Xianming Wang,

W. Wen

и другие.

Green Synthesis and Catalysis, Год журнала: 2023, Номер 5(3), С. 175 - 179

Опубликована: Июль 22, 2023

The nitrile compounds are present in a variety of biologically active natural products and pharmaceuticals, the groups versatile synthetic intermediates to other functionalized compounds. Herein, asymmetric reduction α,β-unsaturated nitriles with water as hydrogen source is reported. reaction catalyzed by complex [Ir(COD)Cl]2 (Ra, S)-Ph-Bn-SiPhox, allows preparation useful enantioenriched chiral 3,3-disubstituted propionitriles high optical purities mild conditions.

Язык: Английский

Процитировано

1
Dearomative electrophilic spirocyclization via the intramolecular Ritter reaction: Diastereoselective access to hydrogenated spiroindolenines DOI
Yuliya S. Rozhkova, Arina S. Pegushina, Vyacheslav V. Morozov

и другие.

Tetrahedron Letters, Год журнала: 2024, Номер 155, С. 155423 - 155423

Опубликована: Дек. 9, 2024

Язык: Английский

Процитировано

0
Enantioselective Synthesis of α-Chiral Amides by Catalytic Hydrogenation with Iridium N,P-Complexes DOI
Bram B. C. Peters, Norman Birke, Pher G. Andersson

и другие.

Synlett, Год журнала: 2022, Номер 34(12), С. 1519 - 1523

Опубликована: Дек. 22, 2022

Abstract The catalytic asymmetric hydrogenation of olefins constitutes a powerful method for the preparation chiral compounds. A series prochiral unsaturated amides were efficiently reduced with high enantioselectivities by means an iridium N,P-complex-catalyzed hydrogenation. Its application in synthesis fenpropidin and possibility using isomeric mixtures starting materials are attractive features method.

Язык: Английский

Процитировано

1
Phosphine Ligand Development for Homogeneous Asymmetric Hydrogenation DOI
Graham E. Dobereiner, Xumu Zhang, Heng Wang

и другие.

Elsevier eBooks, Год журнала: 2021, Номер unknown, С. 1 - 31

Опубликована: Дек. 28, 2021

Язык: Английский

Процитировано

0