Asian Journal of Organic Chemistry,
Год журнала:
2022,
Номер
11(2)
Опубликована: Янв. 21, 2022
Abstract
An
efficient
iron‐catalyzed
allylation
of
cycloalkyl
hydroperoxides
with
allylic
sulfones
via
C−C
bond
cleavage
is
presented.
This
protocol
provides
an
approach
to
a
wide
range
distally
allylated
ketones
good
functional
group
tolerance
and
high
regioselectivity
under
redox‐neutral
conditions.
Preliminary
mechanistic
study
implies
radical
process
might
be
involved
in
this
reaction.
Chemistry - An Asian Journal,
Год журнала:
2021,
Номер
16(17), С. 2431 - 2434
Опубликована: Июль 19, 2021
Abstract
We
describe
a
catalytic
method
for
the
synthesis
of
variety
functionalized
aliphatic
acid
esters
using
silylperoxyacetals,
which
are
versatile
alkyl
radical
precursors
with
terminal
ester
moiety.
In
presence
an
appropriate
transition‐metal
catalyst,
in
situ
generation
radicals
and
subsequent
bond‐forming
process
proceeds
smoothly
to
afford
synthetically
valuable
derivatives.
The
present
can
be
applied
efficient
pharmaceutically
important
1,1‐diarylalkane
motif.
addition,
novel
strategy
structurally
diverse
hydroxy
derivatives
via
C−O
bond
formation
that
utilizes
TEMPO
has
been
developed.
Organic Chemistry Frontiers,
Год журнала:
2023,
Номер
10(19), С. 4821 - 4826
Опубликована: Янв. 1, 2023
A
copper-catalyzed
C(sp
2
)–H
alkylsulfonylation
of
alkenes
using
alkylsilyl
peroxides
as
the
alkyl
radical
precursors
with
insertion
sulfur
dioxide
was
developed,
and
shown
to
provide
a
convenient
route
diverse
(
E
)-alkylsulfonyl
alkenes.
Asian Journal of Organic Chemistry,
Год журнала:
2024,
Номер
13(11)
Опубликована: Авг. 23, 2024
Abstract
Cu‐
and
Fe‐
catalyzed
trideuteromethylation
reactions
using
alkylsilyl
peroxide
as
trideuteromethyl
radical
precursor
are
reported.
The
was
synthesized
from
acetone‐d6
in
a
three‐step
sequence,
the
with
various
coupling
partners
afforded
efficiently
corresponding
N−CD
3
,
O−CD
C−CD
bond
formation
products.
heptadeuteriopropylation
prepared
butyric
acid‐d7
is
also
described.
Asian Journal of Organic Chemistry,
Год журнала:
2022,
Номер
11(2)
Опубликована: Янв. 21, 2022
Abstract
An
efficient
iron‐catalyzed
allylation
of
cycloalkyl
hydroperoxides
with
allylic
sulfones
via
C−C
bond
cleavage
is
presented.
This
protocol
provides
an
approach
to
a
wide
range
distally
allylated
ketones
good
functional
group
tolerance
and
high
regioselectivity
under
redox‐neutral
conditions.
Preliminary
mechanistic
study
implies
radical
process
might
be
involved
in
this
reaction.
