Chinese Journal of Chemical Engineering, Год журнала: 2022, Номер 59, С. 32 - 41
Опубликована: Дек. 9, 2022
Язык: Английский
Small, Год журнала: 2022, Номер 18(36)
Опубликована: Апрель 9, 2022
Abstract Nanoparticles (NPs) have attracted tremendous interest in drug delivery the past decades. Microfluidics offers a promising strategy for making NPs due to its capability precisely controlling NP properties. The recent success of mRNA vaccines using microfluidics represents big milestone microfluidic pharmaceutical applications, and rapid scaling up demonstrates feasibility industrial‐scale manufacturing. This article provides critical review progress delivery. First, synthesis organic focusing on typical methods their applications popular clinically relevant NPs, such as liposomes, lipid polymer well mechanisms are summarized. Then, several representative inorganic (e.g., silica, metal, metal oxide, quantum dots), hybrid is discussed. Lastly, various presented.
Язык: Английский
Процитировано
175
Nature Reviews Materials, Год журнала: 2022, Номер 7(6), С. 428 - 448
Опубликована: Янв. 13, 2022
Язык: Английский
Процитировано
90
Chemical Engineering Journal, Год журнала: 2024, Номер 490, С. 151661 - 151661
Опубликована: Апрель 26, 2024
Язык: Английский
Процитировано
41
Small, Год журнала: 2025, Номер unknown
Опубликована: Янв. 5, 2025
An adjustable and scalable method for the continuous flow synthesis of cupric oxide nanoparticles (CuO NPs), targetted reduction their activity to synthetic biomembranes inform fabrication (NPs) with reduced toxicity commercial applications. By manipulating key factors; temperature, residence time, ratio precursor reductant, precise control over morphology CuO NPs is achieved X-ray diffraction (XRD) transmission electron microscopy (TEM) confirming formation needle-shaped NPs. One-variable-at-a-time studies reveal a relationship between conditions characteristics resultant NPs, varying controllably 10-50 nanometres in length 4-10 width. Subsequently, Design Experiment (DoE) exploration biomembrane intriguingly revealed only minimal effects on membrane-disruptive properties chemical space defined by explored. This study marks significant milestone, as it introduces facile, easy scale, width needle reveals that, regardless exact shape, have impact biomembranes, prompting more detailed future use biomedical
Язык: Английский
Процитировано
3
The Science of The Total Environment, Год журнала: 2021, Номер 810, С. 151997 - 151997
Опубликована: Ноя. 27, 2021
Язык: Английский
Процитировано
77
NPG Asia Materials, Год журнала: 2022, Номер 14(1)
Опубликована: Авг. 12, 2022
Abstract Nanoparticles play irreplaceable roles in optoelectronic sensing, medical therapy, material science, and chemistry due to their unique properties. There are many synthetic pathways used for the preparation of nanoparticles, different can produce nanoparticles with Therefore, it is crucial control properties precisely impart desired functions. In general, influenced by sizes morphologies. Current technology on microfluidic chips requires repeated experimental debugging significant resources synthesize Machine learning-assisted synthesis a sensible choice addressing this challenge. paper, we review recent studies syntheses assisted machine learning. Moreover, describe working steps learning, main algorithms, ways obtain datasets. Finally, discuss current problems research provide an outlook.
Язык: Английский
Процитировано
51
Nanoscale, Год журнала: 2022, Номер 14(18), С. 6688 - 6708
Опубликована: Янв. 1, 2022
The synthesis of nanoparticles is affected by many reaction conditions, and their properties are usually determined factors such as size, shape surface chemistry. In order for the synthesized to have functions suitable different fields (for example, optics, electronics, sensor applications so on), precise control essential. However, with current technology preparing on a microreactor, it time-consuming laborious achieve synthesis. improve efficiency synthesizing expected functionality, application machine learning-assisted an intelligent choice. this article, we mainly introduce typical methods microreactors, explain principles procedures learning, well main ways obtaining data sets. We studied three types representative nanoparticle preparation assisted learning. Finally, problems in future development prospects discussed.
Язык: Английский
Процитировано
45
Nanoscale Advances, Год журнала: 2024, Номер 7(1), С. 42 - 59
Опубликована: Ноя. 22, 2024
The study on the synthesis of carbon dots, sensing mechanisms, conditions associated with glucose imbalance, and potential applications as promising materials for sensors.
Язык: Английский
Процитировано
15
Microchemical Journal, Год журнала: 2025, Номер unknown, С. 112889 - 112889
Опубликована: Янв. 1, 2025
Процитировано
2
Smart Medicine, Год журнала: 2023, Номер 2(1)
Опубликована: Фев. 1, 2023
Abstract Optical biosensors are platforms that translate biological information into detectable optical signals, and have extensive applications in various fields due to their characteristics of high sensitivity, specificity, dynamic sensing, etc. The development sensing materials is an important part sensors. In this review, we emphasize the role microfluidic technology preparation application derived sensors biomedical field. We first present some common mechanisms functional responsive involved. Then, describe these by microfluidics. Afterward, enumerate as disease diagnosis, drug evaluation, organ‐on‐a‐chip. Finally, discuss challenges prospects
Язык: Английский
Процитировано
22