Photoredox catalysis harvesting multiple photon or electrochemical energies

Beilstein Journal of Organic Chemistry, Год журнала: 2023, Номер 19, С. 1055 - 1145

Опубликована: Июль 28, 2023

Photoredox catalysis (PRC) is a cutting-edge frontier for single electron-transfer (SET) reactions, enabling the generation of reactive intermediates both oxidative and reductive processes via photon activation catalyst. Although this represents significant step towards chemoselective and, more generally, sustainable chemistry, its efficacy limited by energy visible light photons. Nowadays, excellent alternative conditions are available to overcome these limitations, harvesting two different but correlated concepts: use multi-photon such as consecutive photoinduced electron transfer (conPET) combination photo- electrochemistry in synthetic photoelectrochemistry (PEC). Herein, we review most recent contributions fields activations organic functional groups. New opportunities chemists captured, selective reactions employing super-oxidants super-reductants engage unactivated chemical feedstocks, scalability up gram scales continuous flow. This provides comparisons between techniques (multi-photon photoredox PEC) help reader fully understand their similarities, differences potential applications therefore choose which method appropriate given reaction, scale purpose project.

Язык: Английский

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Visible-light induced eosin Y catalysed C(sp2)-H alkylation of carbonyl substrates via direct HAT

Tetrahedron, Год журнала: 2023, Номер 132, С. 133245 - 133245

Опубликована: Янв. 5, 2023

Язык: Английский

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Metal-free visible light mediated direct C–H amination of benzoxazole with secondary amines

Molecular Diversity, Год журнала: 2023, Номер 28(1), С. 61 - 71

Опубликована: Янв. 7, 2023

Язык: Английский

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Photoinduced Decarboxylative Radical Phosphinylation

Angewandte Chemie International Edition, Год журнала: 2024, Номер 63(8)

Опубликована: Янв. 5, 2024

Abstract Reported herein is an unprecedented protocol for C(sp 3 )‐phosphinylation. With 1 mol % 4CzIPN (1,2,3,5‐tetrakis(carbazol‐9‐yl)‐4,6‐dicyanobenzene) as the catalyst, visible light induced reaction of redox‐active esters aliphatic carboxylic acids with dimethyl arylphosphonites or diethyl alkylphosphonites at room temperature provides corresponding decarboxylative phosphinylation products in satisfactory yields. The exhibits broad substrate scope and wide functional‐group compatibility, enabling late‐stage modification complex molecules rapid synthesis bioactive phosphinic such glutamine synthetase phosphinothricin a kynureninase inhibitor. A radical‐polar crossover mechanism involving formation subsequent oxidation phosphoranyl radicals followed by nucleophilic demethylation (or deethylation) proposed.

Язык: Английский

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Novel applications of photobiocatalysts in chemical transformations

RSC Advances, Год журнала: 2024, Номер 14(4), С. 2590 - 2601

Опубликована: Янв. 1, 2024

Photocatalysis has proven to be an effective approach for the production of reactive intermediates under moderate reaction conditions.

Язык: Английский

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