Sensors and Actuators A Physical, Год журнала: 2023, Номер 356, С. 114363 - 114363
Опубликована: Апрель 11, 2023
Язык: Английский
Polymers, Год журнала: 2021, Номер 13(7), С. 1105 - 1105
Опубликована: Март 30, 2021
Tissue engineering (TE) and regenerative medicine integrate information technology from various fields to restore/replace tissues damaged organs for medical treatments. To achieve this, scaffolds act as delivery vectors or cellular systems drugs cells; thereby, material is able colonize host cells sufficiently meet up the requirements of regeneration repair. This process multi-stage requires development components create desired neo-tissue organ. In several current TE strategies, biomaterials are essential components. While polymers established their use biomaterials, careful consideration environment interactions needed required in selecting a polymer given application. Depending on scaffold materials can be natural synthetic origin, degradable nondegradable. this review, an overview possible composite with physicochemical properties including biocompatibility, biodegradability, morphology, mechanical strength, pore size, porosity discussed. The fabrication techniques few commercially available biopolymers also tabulated.
Язык: Английский
Процитировано
734
Advanced Functional Materials, Год журнала: 2021, Номер 31(34)
Опубликована: Июнь 17, 2021
Abstract Real‐time monitoring of wound healing remains a major challenge in clinical tissue regeneration, calling the need for development biomaterial‐guided on‐site technology. In this study, multifunctional double colorimetry‐integrated polyacrylamide‐quaternary ammonium chitosan‐carbon quantum dots (CQDs)‐phenol red hydrogels are presented, aiming to simultaneously detect pH level, reduce bacterial infection, and promote healing. The hybridization CQDs indicator (phenol red) with enables their high responsiveness, reversibility, accurate indication variability reflect dynamic status context both ultraviolet visible light. Furthermore, these visual images can be collected by smartphones converted into signals, allowing real‐time evaluation conditions remote approach. Notably, exhibit excellent hemostatic adhesive properties, maintain sufficient moisture, via antibacterial activity (against Staphylococcus Aureus , Escherichia Coli ) skin repair function. Overall, resulting have potential as novel smart flexible dressing platform theranostic regeneration.
Язык: Английский
Процитировано
216
International Journal of Biological Macromolecules, Год журнала: 2022, Номер 218, С. 601 - 633
Опубликована: Июль 25, 2022
Язык: Английский
Процитировано
196
Asian Journal of Pharmaceutical Sciences, Год журнала: 2023, Номер 18(3), С. 100812 - 100812
Опубликована: Апрель 27, 2023
Biopolymers are promising environmentally benign materials applicable in multifarious applications. They especially favorable implantable biomedical devices thanks to their excellent unique properties, including bioactivity, renewability, bioresorbability, biocompatibility, biodegradability and hydrophilicity. Additive manufacturing (AM) is a flexible intricate technology, which widely used fabricate biopolymer-based customized products structures for advanced healthcare systems. Three-dimensional (3D) printing of these sustainable applied functional clinical settings wound dressing, drug delivery systems, medical implants tissue engineering. The present review highlights recent advancements different types biopolymers, such as proteins polysaccharides, employed develop by using extrusion, vat polymerization, laser inkjet 3D techniques addition normal bioprinting four-dimensional (4D) techniques. This also incorporates the influence nanoparticles on biological mechanical performances 3D-printed scaffolds. work addresses current challenges well future developments friendly polymeric manufactured through AM Ideally, there need more focused research adequate blending biodegradable biopolymers achieving useful results targeted areas. We envision that composites have potential revolutionize sector near future.
Язык: Английский
Процитировано
157
Macromolecular Bioscience, Год журнала: 2022, Номер 22(7)
Опубликована: Апрель 7, 2022
Abstract As the first defensive line between human body and outside world, skin is vulnerable to damage from external environment. Skin wounds can be divided into acute (mechanical injuries, chemical surgical wounds, etc.) chronic (burns, infections, diabetes, etc.). In order manage wound, a variety of wound dressings have been developed, including gauze, films, foams, nanofibers, hydrocolloids, hydrogels. Recently, hydrogels received much attention because their natural extracellular matrix (ECM)‐mimik structure, tunable mechanical properties, facile bioactive substance delivery capability. They show great potential application in repair. This paper introduces anatomy function skin, process healing conventional dressings, then composition construction methods Next, this necessary properties repair latest research progress hydrogel for Finally, future development goals materials field are proposed.
Язык: Английский
Процитировано
150
Gels, Год журнала: 2022, Номер 8(2), С. 127 - 127
Опубликована: Фев. 17, 2022
Chronic wounds severely affect 1-2% of the population in developed countries. It has been reported that nearly 6.5 million people United States suffer from at least one chronic wound their lifetime. The treatment is critical for maintaining physical and mental well-being patients improving quality life. There are a host methods wounds, including debridement, hyperbaric oxygen therapy, ultrasound, electromagnetic therapies, negative pressure skin grafts, hydrogel dressings. Among these, dressings represent promising viable choice because tunable functional properties, such as biodegradability, adhesivity, antimicrobial, anti-inflammatory, pre-angiogenic bioactivities, can accelerate healing wounds. This review summarizes types phases process, key therapeutic approaches. Hydrogel-based reviewed multifunctional properties advantages Examples commercially available also provided to demonstrate effectiveness over other healing.
Язык: Английский
Процитировано
148
Polymer Chemistry, Год журнала: 2021, Номер 12(26), С. 3721 - 3739
Опубликована: Янв. 1, 2021
Due to their outstanding properties, bioadhesive hydrogels have been extensively studied by researchers in recent years.
Язык: Английский
Процитировано
126
Carbohydrate Polymers, Год журнала: 2021, Номер 276, С. 118718 - 118718
Опубликована: Окт. 2, 2021
Язык: Английский
Процитировано
126
Biomaterials Science, Год журнала: 2022, Номер 10(15), С. 4058 - 4076
Опубликована: Янв. 1, 2022
Multifunctional wound dressings or smart with pro-angiogenic function, antibacterial properties, anti-inflammatory/antioxidant activity and tissue adhesion for chronic repair.
Язык: Английский
Процитировано
95
Advanced Engineering Materials, Год журнала: 2023, Номер 25(21)
Опубликована: Авг. 29, 2023
Stimuli‐responsive polymers (SRPs) are special types of soft materials, which have been extensively used for developing flexible actuators, robots, wearable devices, sensors, self‐expanding structures, and biomedical thanks to their ability change shapes functional properties in response external stimuli including light, humidity, heat, pH, electric field, solvent, magnetic field or combinations two more these stimuli. In recent years, additive manufacturing (AM) aka 3D printing technology SRPs, also known as 4D printing, has gained phenomenal attention different engineering fields, its unique develop complex, personalized, innovative undergo twisting, elongating, swelling, rolling, shrinking, bending, spiraling, other complex morphological transformations. Herein, an effort made provide insightful information about the AM techniques, type applications including, but not limited tissue engineering, bionics, construction, smart textiles. This article incorporates current challenges prospects, hoping basis utilization this fields. It is expected that amalgamation with SRPs would unparalleled advantages arenas.
Язык: Английский
Процитировано
87