Chemical Communications,
Год журнала:
2022,
Номер
58(67), С. 9409 - 9412
Опубликована: Янв. 1, 2022
Sulfonyl
fluorides
are
emerging
as
key
structural
motifs
in
organic
synthesis,
medicinal
chemistry,
and
materials
science.
Herein
we
report
two
efficient
complementary
methods
for
direct
decarboxylative
fluorosulfonylation
of
carboxylic
acids
by
the
merging
copper
catalysis
with
different
N-centered
HAT
regents.
A
wide
range
structurally
diverse
sulfonyl
was
readily
accessed
from
primary,
secondary,
tertiary
a
single
step
under
mild
conditions.
Green Chemistry,
Год журнала:
2024,
Номер
26(11), С. 6774 - 6778
Опубликована: Янв. 1, 2024
A
novel
and
attractive
photochemical
difunctionalization
of
N
-tosyl
acrylamide
for
constructing
alkylsulfonylated
oxindoles
amides
with
excellent
substrate
adaptability
via
a
radical
Smiles
rearrangement
strategy
is
described.
Chemistry - A European Journal,
Год журнала:
2024,
Номер
30(21)
Опубликована: Фев. 9, 2024
Abstract
A
novel
electrochemical
approach
to
access
alkyl
alkenesulfonates
via
a
multicomponent
reaction
was
developed.
The
metal‐free
method
features
easy‐to‐use
SO
2
stock
solution
forming
monoalkylsulfites
from
alcohols
with
an
auxiliary
base
in‐situ.
These
intermediates
serve
dual
role
as
starting
materials
and
supporting
electrolyte
enabling
conductivity.
Anodic
oxidation
of
the
substrate
styrene,
radical
addition
these
consecutive
second
deprotonation
preserve
double
bond
form
β‐styrenesulfonates
in
highly
regio‐
stereoselective
fashion.
feasibility
this
electrosynthetic
is
demonstrated
44
examples
yields
up
81
%,
employing
various
styrenes
related
substrates
well
diverse
set
alcohols.
gram‐scale
experiment
underlines
applicability
process,
which
uses
inexpensive
readily
available
electrode
materials.
ACS Catalysis,
Год журнала:
2022,
Номер
12(3), С. 1986 - 1991
Опубликована: Янв. 21, 2022
A
visible-light-mediated
late-stage
arylation
of
N–S
bonds
in
sulfonamides
has
been
developed
with
using
readily
available
imines
as
sulfonyl
radical
source.
Diverse
complex
sulfones
could
be
synthesized
by
prefunctionalizaiton
and
subsequent
bond
arylation,
demonstrating
the
advantages
sulfonylation
reagents.
Additionally,
mechanism
research
revealed
that
probably
both
EDA
chemistry
photoredox
catalysis
were
responsible
for
formation
sulfones.
This
methodology
characterized
broad
substrate
scope
simple
reaction
conditions
also
high
atom
economy,
since
aldehyde
synthesis
recovered
after
workup
reactions.
Chemical Communications,
Год журнала:
2022,
Номер
58(67), С. 9409 - 9412
Опубликована: Янв. 1, 2022
Sulfonyl
fluorides
are
emerging
as
key
structural
motifs
in
organic
synthesis,
medicinal
chemistry,
and
materials
science.
Herein
we
report
two
efficient
complementary
methods
for
direct
decarboxylative
fluorosulfonylation
of
carboxylic
acids
by
the
merging
copper
catalysis
with
different
N-centered
HAT
regents.
A
wide
range
structurally
diverse
sulfonyl
was
readily
accessed
from
primary,
secondary,
tertiary
a
single
step
under
mild
conditions.
