Next Materials, Год журнала: 2025, Номер 8, С. 100617 - 100617
Опубликована: Март 29, 2025
Язык: Английский
Advanced Functional Materials, Год журнала: 2024, Номер unknown
Опубликована: Сен. 27, 2024
Abstract Biomaterials that integrate multiple functionalities, mimic the extracellular matrix (ECM) microenvironment to support cellular growth, and adhere robustly damaged tissues are highly needed advance tissue engineering. Protein‐based biomaterials promising due their inherent biocompatibility, biomimicry, biodegradation, cell‐supportive properties. Herein, by leveraging unique ability of dithiolanes generate on‐demand in situ thiols, a new class dithiolane‐modified, protein‐based biomaterial combines unique, seemingly opposing functions for engineering is developed. Dithiolane‐modified gelatin, model protein used herein, enabled photoinitiator‐free photo‐crosslinking form multi‐functional gelatin‐dithiolane (GelDT) hydrogels, which displayed exceptional long‐term stability cell culture media (>28 days) growth both surface‐seeded encapsulated cells. GelDT hydrogels allowed pre‐gelation tuning biomechanical properties biodegradation via introducing physical crosslinks, post‐gelation stress‐relaxation rate, responding exogenous independently other parameters. Furthermore, covalent immobilization bio‐active molecules, glutathione‐responsive drug release, supported efficient 3D bioprinting its shear‐thinning ability, demonstrated robust adhesion various contexts (bare skin, ex‐vivo, in‐vivo) disulfide coupling with endogenous thiols. Together, this study presents novel multi‐responsive biomaterial, anticipated regeneration.
Язык: Английский
Процитировано
4
Coatings, Год журнала: 2023, Номер 13(1), С. 110 - 110
Опубликована: Янв. 7, 2023
Developing environmentally friendly UV-curable polymers with multi-functionality is very significant for sustainable development and environmental protection. In this work, a novel tung-oil-based oligomer (TOMAH) was synthesized by Diels–Alder ring-opening reactions via microwave technology. Subsequently, catalyst-free self-healing materials based on maleate monoester transesterification (MMETER) were developed co-photopolymerization of TOMAH hydroxyethyl methacrylate (HEMA). The obtained UV-cured possessed high glass transition temperature (Tg > 81 °C), excellent adhesion (grade 1), flexibility (2 mm). Particularly, the outstanding photopolymerization activity resins proved UV-curing kinetics. addition, dynamic transesterifications occurred without an external catalyst at moderate temperature, resulting in good properties (with scratch-repair efficiency 78.6–93.3%) shape-memory materials. This work combines multiple advantages biomass raw material, synthesis technology, method, multifunctional polymers, thus providing innovative strategy to fabricate intelligent coatings.
Язык: Английский
Процитировано
10
Chemical Science, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
We report a photo-regulated disulfide crosslinking strategy to construct mucus-mimetic hydrogels. Light-responsive 1,2-dithiolane on linear polyglycerol sulfate (lPGS) enables dynamic and forms biohybrid hydrogel with native mucin.
Язык: Английский
Процитировано
0
Journal of the American Chemical Society, Год журнала: 2025, Номер unknown
Опубликована: Март 10, 2025
The ability to arrange brightly fluorescent nanoscale materials into well-defined patterns is critically important in advanced optoelectronic structures. Traditional methods for doing so generally involve depositing different color quantum dot "inks," irradiating reactive (e.g., cross-linkable) ligands at their surface, and then lifting off the unexposed sections a developer solvent. Here, we outline fundamentally approach directly patterning emission of nanocomposite thin films utilizing mask-based lithographic techniques laser scanning methods. In this system, polymer film containing cesium lead halide nanocrystals (NCs) embedded with an organohalide─termed "photohalide generator"─which undergoes light-triggered, perovskite-catalyzed reduction release anion uptake by NC lattice, markedly shifting its band gap. manner, blue emitting (CsPbBr1.5Cl1.5) becomes green and/or red exposed areas photomask, replicating mask features as multichromatic array green, red, etc. colors against background). resolution limits system were probed using tools capable writing intricate feature sizes approaching single micron─more than order magnitude smaller most comparable based on inkjet printing. Lastly, these are extended combined shape process making free-standing filamentous structures striped alternating fluorescence along length.
Язык: Английский
Процитировано
0
Next Materials, Год журнала: 2025, Номер 8, С. 100617 - 100617
Опубликована: Март 29, 2025
Язык: Английский
Процитировано
0