Angewandte Chemie International Edition,
Год журнала:
2022,
Номер
61(37)
Опубликована: Июнь 21, 2022
The
Brook
rearrangement
has
already
become
established
as
one
of
the
most
important
molecular
rearrangements
in
synthetic
chemistry
and
been
applied
generation
complexes,
drug
discovery,
material
science,
natural
products
synthesis.
Compared
to
widely
known
ionic
mechanism,
radical
is
less
explored
because
difficulty
generating
alkoxyl
species.
This
Minireview
summarizes
early
developments
general
concept
highlights
recent
advances
photocatalytic
reactions
transition-metal-catalyzed
cross-coupling
involving
rearrangements.
We
hope
this
survey
will
inspire
further
emerging
area.
Journal of the American Chemical Society,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 30, 2025
Epoxides
are
significant
chemicals
that
utilized
across
various
fields.
Here,
we
describe
an
unprecedented
photochemical
rearrangement
approach
for
synthesizing
a
diverse
collection
of
epoxides
enabled
by
energy
transfer
catalysis
under
visible
light
conditions.
The
process
enables
the
easy
preparation
α-amino-substituted
epoxide
derivatives
with
broad
substrate
scope,
functional
group
tolerance,
and
mild
reaction
Furthermore,
this
photorearrangement
has
also
been
applied
in
complex
architectures,
could
be
easily
transferred
to
amino
alcohol
derivatives.
Overall,
oxa-π,
σ-methane
provides
complementary
strategy
existing
methods
through
catalysis.
The Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 5, 2025
In
this
study,
we
present
a
novel
catalyst-free
energy
transfer
mediated
radical
rearrangement
strategy
for
the
aryl-heterofunctionalization
of
unactivated
alkynes,
leading
to
synthesis
polyfunctional
olefins
with
exceptional
stereoselectivity.
This
innovative
approach,
driven
by
visible
light,
exemplifies
green
chemistry
principles
eliminating
reliance
on
transition
metals,
external
oxidants,
and
photocatalysts.
The
broad
applicability
our
method
is
demonstrated
through
successful
diverse
array
compounds,
including
vinyl
sulfones,
selenides,
sulfides.
Preliminary
mechanistic
insights
suggest
an
mechanism,
highlighting
efficiency
selectivity
strategy.
Angewandte Chemie International Edition,
Год журнала:
2022,
Номер
61(37)
Опубликована: Июнь 21, 2022
The
Brook
rearrangement
has
already
become
established
as
one
of
the
most
important
molecular
rearrangements
in
synthetic
chemistry
and
been
applied
generation
complexes,
drug
discovery,
material
science,
natural
products
synthesis.
Compared
to
widely
known
ionic
mechanism,
radical
is
less
explored
because
difficulty
generating
alkoxyl
species.
This
Minireview
summarizes
early
developments
general
concept
highlights
recent
advances
photocatalytic
reactions
transition-metal-catalyzed
cross-coupling
involving
rearrangements.
We
hope
this
survey
will
inspire
further
emerging
area.
