Biotechnology and Genetic Engineering Reviews,
Год журнала:
2023,
Номер
unknown, С. 1 - 14
Опубликована: Фев. 28, 2023
Microorganisms
produce
secondary
metabolites
to
survive
under
stressful
conditions.
The
effect
of
drought
and
heat
stress
on
fungi
isolated
from
Arabian
desert
soil
during
the
hot
(ca
40°C)
cool
10°C)
seasons
was
studied
using
genome
mining
approach.
presence
three
stress-related
genes
(calmodulin,
polyketide
synthase
beta
tubulin)
analyzed
molecularly
specific
primers.
in
compared
their
antimicrobial
(ten
bacterial
or
fungal
pathogens)
anticancer
(liver,
cervical
breast)
properties
production
thermostable
enzymes
(phytase
xylanase).
appeared
be
present
sequence
obtained
summer,
while
none
were
winter.
Appreciable
differences
observed
enzyme
activities,
with
summer
activities
high
winter
low.
antagonistic
A.
niger
relatively
stable
varying,
those
P.
chrysogenum
consistently
higher
than
seemed
correlate
highly
chrysogenum,
had
active
isolates
without
any
genes.
season
deserts
yields
biological
useful
biotechnological
solutions.
Organic Chemistry Frontiers,
Год журнала:
2022,
Номер
9(23), С. 6579 - 6585
Опубликована: Янв. 1, 2022
A
palladium-catalyzed
Lewis
acid-regulated
cascade
annulation
of
alkynes
with
unactivated
alkenes
for
the
preparation
alkyl
substituted
α-methylene-γ-lactones
excellent
Z
/
E
selectivities
was
accomplished.
Natural Product Research,
Год журнала:
2022,
Номер
37(11), С. 1872 - 1876
Опубликована: Сен. 6, 2022
The
current
study
attempted
to
evaluate
the
antagonistic
activity
of
compounds
isolated
and
purified
from
marine
algae
Padina
arborescens
during
cultivation.
were
collected
on
a
filter,
concentrated
ODS
columns
separated
by
HPLC.
Two
peaks
that
showed
competitive
progesterone
binding
with
membrane
receptor
α
(mPRα)
purified.
Their
physiological
was
further
uncovered
in
vitro
vivo
oocyte
maturation
ovulation-inducing
assays
using
zebrafish.
inhibited
induction
ovulation.
Moreover,
results
have
against
mPRα.
mPRα
would
be
considered
as
new
pharmaceutical
candidate.
RSC Advances,
Год журнала:
2022,
Номер
12(26), С. 16530 - 16534
Опубликована: Янв. 1, 2022
An
organobase-catalyzed
1,1-diborylation
of
terminal
alkynes
from
propargylic
derivatives
with
B
2
oct
is
first
reported,
providing
1,1-diborylalkene
products
high
efficiency.
The
catalytic
pathway
well
postulated
on
the
basis
DFT
calculations.
ACS Omega,
Год журнала:
2022,
Номер
7(47), С. 43068 - 43083
Опубликована: Ноя. 16, 2022
Sponges
are
prolific
producers
of
specialized
metabolites
with
unique
structural
scaffolds.
Their
chemical
diversity
has
always
inspired
natural
product
chemists
working
in
drug
discovery.
As
part
their
metabolic
filter-feeding
activities,
sponges
known
to
release
molecules,
possibly
including
metabolites.
These
released
"Exo-Metabolites"
(EMs)
may
be
considered
as
new
reservoirs
that
could
collected
from
the
water
column
while
preserving
marine
biodiversity.
The
present
work
aims
determine
proportion
and
EMs
by
sponge
Biotechnology and Genetic Engineering Reviews,
Год журнала:
2023,
Номер
unknown, С. 1 - 14
Опубликована: Фев. 28, 2023
Microorganisms
produce
secondary
metabolites
to
survive
under
stressful
conditions.
The
effect
of
drought
and
heat
stress
on
fungi
isolated
from
Arabian
desert
soil
during
the
hot
(ca
40°C)
cool
10°C)
seasons
was
studied
using
genome
mining
approach.
presence
three
stress-related
genes
(calmodulin,
polyketide
synthase
beta
tubulin)
analyzed
molecularly
specific
primers.
in
compared
their
antimicrobial
(ten
bacterial
or
fungal
pathogens)
anticancer
(liver,
cervical
breast)
properties
production
thermostable
enzymes
(phytase
xylanase).
appeared
be
present
sequence
obtained
summer,
while
none
were
winter.
Appreciable
differences
observed
enzyme
activities,
with
summer
activities
high
winter
low.
antagonistic
A.
niger
relatively
stable
varying,
those
P.
chrysogenum
consistently
higher
than
seemed
correlate
highly
chrysogenum,
had
active
isolates
without
any
genes.
season
deserts
yields
biological
useful
biotechnological
solutions.
