Diving into the Molecular Diversity of Aplysina cavernicola’s Exometabolites: Contribution of Bromo-Spiroisoxazoline Alkaloids DOI Creative Commons
Morgane Mauduit, Stéphane Greff, Gaëtan Herbette

и другие.

ACS Omega, Год журнала: 2022, Номер 7(47), С. 43068 - 43083

Опубликована: Ноя. 16, 2022

Sponges are prolific producers of specialized metabolites with unique structural scaffolds. Their chemical diversity has always inspired natural product chemists working in drug discovery. As part their metabolic filter-feeding activities, sponges known to release molecules, possibly including metabolites. These released "Exo-Metabolites" (EMs) may be considered as new reservoirs that could collected from the water column while preserving marine biodiversity. The present work aims determine proportion and EMs by sponge

Язык: Английский

Marine Specialized Metabolites : Unveiling Nature's Chemical Treasures from the Deep Blue DOI Creative Commons
Thilina U. Jayawardena, Natacha Mérindol, Nuwan Sameera Liyanage

и другие.

TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер unknown, С. 118097 - 118097

Опубликована: Дек. 1, 2024

Язык: Английский

Процитировано

2

Palladium-catalyzed Lewis acid-regulated cascade annulation of alkynes with unactivated alkenes to access diverse α-methylene-γ-lactones DOI
Jianxiao Li, Dan He, Bowen Wang

и другие.

Organic Chemistry Frontiers, Год журнала: 2022, Номер 9(23), С. 6579 - 6585

Опубликована: Янв. 1, 2022

A palladium-catalyzed Lewis acid-regulated cascade annulation of alkynes with unactivated alkenes for the preparation alkyl substituted α-methylene-γ-lactones excellent Z / E selectivities was accomplished.

Язык: Английский

Процитировано

9

The antagonistic activity of Padina arborescens extracts on mPRα DOI
Mrityunjoy Acharjee, Md Hasan Ali, Md. Maisum Sarwar Jyoti

и другие.

Natural Product Research, Год журнала: 2022, Номер 37(11), С. 1872 - 1876

Опубликована: Сен. 6, 2022

The current study attempted to evaluate the antagonistic activity of compounds isolated and purified from marine algae Padina arborescens during cultivation. were collected on a filter, concentrated ODS columns separated by HPLC. Two peaks that showed competitive progesterone binding with membrane receptor α (mPRα) purified. Their physiological was further uncovered in vitro vivo oocyte maturation ovulation-inducing assays using zebrafish. inhibited induction ovulation. Moreover, results have against mPRα. mPRα would be considered as new pharmaceutical candidate.

Язык: Английский

Процитировано

7

Organobase-catalyzed 1,1-diborylation of terminal alkynes under metal-free conditions DOI Creative Commons
Junchen Li, Min An, Zhenhua Gao

и другие.

RSC Advances, Год журнала: 2022, Номер 12(26), С. 16530 - 16534

Опубликована: Янв. 1, 2022

An organobase-catalyzed 1,1-diborylation of terminal alkynes from propargylic derivatives with B 2 oct is first reported, providing 1,1-diborylalkene products high efficiency. The catalytic pathway well postulated on the basis DFT calculations.

Язык: Английский

Процитировано

6

Diving into the Molecular Diversity of Aplysina cavernicola’s Exometabolites: Contribution of Bromo-Spiroisoxazoline Alkaloids DOI Creative Commons
Morgane Mauduit, Stéphane Greff, Gaëtan Herbette

и другие.

ACS Omega, Год журнала: 2022, Номер 7(47), С. 43068 - 43083

Опубликована: Ноя. 16, 2022

Sponges are prolific producers of specialized metabolites with unique structural scaffolds. Their chemical diversity has always inspired natural product chemists working in drug discovery. As part their metabolic filter-feeding activities, sponges known to release molecules, possibly including metabolites. These released "Exo-Metabolites" (EMs) may be considered as new reservoirs that could collected from the water column while preserving marine biodiversity. The present work aims determine proportion and EMs by sponge

Язык: Английский

Процитировано

4