Communications Chemistry,
Год журнала:
2024,
Номер
7(1)
Опубликована: Дек. 5, 2024
Non-metallic
catalysis
has
been
known
as
a
remarkable
development
strategy
for
hydrofunctionalization
of
unsaturated
hydrocarbons.
Herein,
we
report
unique
chemically
active
method
BF3·OEt2
promoted
multi-component,
highly
regioselective,
and
chemoselective
hydrothio(seleo)phosphonylation
hydrocarbons,
which
exhibits
high
yield
good
substrate
universality.
The
reaction
mechanism
was
further
elucidated
to
be
Markovnikov
addition
by
controlling
experiments,
31P
19F
NMR
spectra
tracking
X-ray
diffraction
analysis,
DFT
calculations.
Furthermore,
the
gram-scale
attempt
application
on
derivatization
natural
products
have
successfully
conducted,
leading
discovery
3as
with
potential
anti-Parkinson's
disease
(PD)
activities
at
1
μM.
This
streamlined
efficient
methodology
established
new
platform
non-metallic
Lewis
acids-promoted
hydrocarbons
its
drug
research.
Transition
metal
catalysts
are
typically
used
however,
such
reactions
time-consuming
may
challenging.
authors
BF3·OEt2-promoted
yields
universality
Journal of the American Chemical Society,
Год журнала:
2023,
Номер
145(32), С. 17527 - 17550
Опубликована: Авг. 2, 2023
The
C–O
bond
is
ubiquitous
in
biologically
active
molecules,
pharmaceutical
agents,
and
functional
materials,
thereby
making
it
an
important
group.
Consequently,
the
development
of
bond-forming
reactions
using
catalytic
strategies
has
become
increasingly
research
topic
organic
synthesis
because
more
conventional
methods
involving
strong
base
acid
have
many
limitations.
In
contrast
to
ionic-pathway-based
methods,
copper-promoted
radical-mediated
formation
experiencing
a
surge
interest
owing
renaissance
free-radical
chemistry
photoredox
catalysis.
This
Perspective
highlights
appraises
state-of-the-art
techniques
this
burgeoning
field.
contents
are
organized
according
different
reaction
types
working
models.
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
11(14), С. 4024 - 4040
Опубликована: Янв. 1, 2024
This
review
provides
a
comprehensive
overview
of
metal
catalysis
in
photo-electrochemical
systems,
discussing
reaction
mechanisms
and
offering
prospects
for
this
triadic
catalytic
mode.
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Фев. 19, 2025
Titania
and
reduced
graphene
oxide
(rGO)
are
well-known
materials
with
excellent
photocatalytic
properties,
but
research
on
the
photocatalytic-based
antibacterial
effects
of
their
combination
remains
limited.
This
study
explored
suitability
titania
nanotubes
(TiO2
NTs)
combined
rGO
two
terminal
functional
groups
(nonfunctional
aminated
(NH2))
as
efficient
photocatalysts
for
antimicrobial
applications
under
visible
light
irradiation.
Field-emission
scanning
electron
microscopy
observations
revealed
that
covered
entire
surface
TiO2
NTs.
Tauc
plots
calculated
from
spectra
diffuse
reflectance
spectroscopy
showed
band
gaps
nonfunctional
amine
rGO-coated
NTs
were
2.40
2.21
eV,
respectively.
Therefore,
all
exhibited
activity
470
nm
An
colony
forming
unit
test
using
S.
aureus
P.
aeruginosa,
enzymatic
tests
(superoxide
dismutase
catalase)
same
bacteria,
visible-light
irradiation
compared
to
uncoated
groups.
In
addition,
MTT
assay
enhanced
cell
viability
after
visible-light-triggered
has
significant
potential
expressing
properties
in
dental
applications.
Chemical Communications,
Год журнала:
2023,
Номер
59(36), С. 5395 - 5398
Опубликована: Янв. 1, 2023
The
first
N-heterocyclic
carbene
organocatalytic
three-component
radical
relay
trifunctionalization
of
unactivated
alkenes
through
the
combination
remote
1,4-cyano
migration
and
alkylacylation
was
reported.
This
protocol
features
mild
reaction
conditions,
readily
available
materials,
excellent
regioselectivity,
capability
late-stage
functionalization.
Organic Letters,
Год журнала:
2023,
Номер
25(22), С. 4056 - 4060
Опубликована: Май 31, 2023
A
Giese
reaction
of
aryl
bromides
with
electron-deficient
alkenes
was
developed,
enabled
by
a
dual
catalyst
system
containing
NiII
complex
and
IrIII
photocatalyst.
This
protocol
could
accommodate
variety
alkenes,
delivering
the
conjugate
adducts
in
up
to
97%
yield.
The
utilization
photoexcited
(dtbbpy)NiII(aryl)Br
intermediate
as
an
radical
source
allows
this
novel
transformation
halides,
thus
expanding
chemical
space
excited
nickel
catalysis.
Polyoxometalates,
Год журнала:
2024,
Номер
4(3), С. 9140080 - 9140080
Опубликована: Окт. 8, 2024
Atomically
precise
copper
nanoclusters
have
emerged
as
a
promising
class
of
catalysts
for
driving
chemical
reactions.
However,
the
exploration
nanocluster
has
been
slow,
likely
due
to
their
complex
synthetic
process,
limited
stability,
and
low
activity
under
mild
conditions.
In
this
study,
we
present
highly
stable
[Cu8(S2CN(CH3)2)6(PPh3)4]2+
(where
S2CN(CH3)2
is
dimethyldithiocarbamate
PPh3
triphenylphosphine)
that
exhibits
facile
protocol
high
photocatalytic
performance.
The
cluster
can
be
easily
obtained
by
reducing
Cu(S2CN(CH3)2)2
with
(PPh3)2CuBH4
in
presence
3,5-bis(trifluoromethyl)pyrazole
one-pot
reaction,
even
yielding
gram-scale
product
through
one-step
process.
A
comprehensive
experimental
theoretical
characterization
provides
deep
understanding
its
atomic
electronic
structure,
which
also
explains
stability
irradiation
treatment.
Importantly,
enables
photo-catalytic
difluoroalkylarylation
alkenes
at
room
temperature,
resulting
wide
range
difluoromethyl
compounds
This
study
not
only
presents
an
efficient
strategy
accessing
atomically
robust
structures,
but
highlights
potential
rapidly
constructing
molecular
complexity
material
economy.
Organic & Biomolecular Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
This
review
summarizes
recent
progress
in
EDA
complex-promoted
C–S
bond
formation
using
various
sulfur-containing
substrates
under
mild
conditions
via
visible
light
irradiation.
Chemistry - A European Journal,
Год журнала:
2023,
Номер
29(35)
Опубликована: Март 15, 2023
A
dual
catalytic
approach
combining
photocatalyst
and
selenium-π-acid
synergy
has
been
used
to
cyclized
of
N-propargylamides.
This
method
offers
readily
access
oxazole
aldehydes
under
chemical
oxidant-free
conditions
with
low
catalyst
loadings,
where
air
acts
as
a
terminal
gratuitous
oxidant.
The
reaction
is
demonstrated
range
substrates,
including
aryl
alkyl
propargyl
amides,
in
the
late-stage
functionalization
several
amide-containing
drug
molecules.
Mechanistic
studies
suggest
that
acridinium
able
oxidize
diselenide
generate
singlet
oxygen
(1
O2
),
which
responsible
for
this
transformation.
