Synthesis,
Год журнала:
2024,
Номер
56(09), С. 1415 - 1421
Опубликована: Янв. 17, 2024
Abstract
An
environmentally
friendly
iodine-promoted
disproportionate
coupling
reaction
of
arylsulfonyl
hydrazides
is
reported.
This
strategy
can
synthesize
thiosulfonates
with
medium
to
excellent
yields,
and
features
a
green
system,
wide
applicability
substrates,
easy
availability
raw
materials.
The
preliminary
mechanistic
study
reveals
that
iodine
plays
an
important
role
in
the
radical
process.
Angewandte Chemie International Edition,
Год журнала:
2024,
Номер
63(8)
Опубликована: Янв. 8, 2024
A
mild
photoredox
catalyzed
construction
of
sulfides,
disulfides,
selenides,
sulfoxides
and
sulfones
from
unstrained
ketone
precursors
is
introduced.
Combination
this
deacylative
process
with
S
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(18), С. 13601 - 13607
Опубликована: Сен. 4, 2024
A
zinc-mediated
cross-electrophile
coupling
of
benzyl
sulfonium
salts
with
thiosulfonates
via
C-S
bond
cleavage
was
achieved.
The
reductive
thiolation
proceeded
well
under
transition
metal-free
conditions
to
afford
the
desired
sulfides
in
good
yields,
exhibiting
both
broad
substrate
scope
and
functionality
tolerance.
In
addition,
reaction
could
be
applied
use
selenosulfonate
as
an
effective
selenylation
agent
subjected
scale-up
synthesis.
Organic Letters,
Год журнала:
2023,
Номер
25(39), С. 7078 - 7082
Опубликована: Сен. 21, 2023
A
metal-free
oxidative
trideuteromethylthiolation
of
alkenes
with
CD3SSO3Na
using
NFSI
as
an
oxidant
has
been
developed.
The
aminotrideuteromethylthiolation
a
three-component
reaction
could
be
easily
achieved
in
the
presence
cobalt
catalyst.
divergent
alkenes,
readily
available
reagent,
and
versatile
synthetic
strategy
allow
for
late-stage
modification
drug
molecules.
Organic Letters,
Год журнала:
2023,
Номер
25(39), С. 7186 - 7191
Опубликована: Сен. 27, 2023
Herein,
we
report
the
first
rhodium-catalyzed
hydrolytic
cleavage
of
silicon–carbon
bond
in
silacyclobutanes
using
water
as
reactant.
A
series
could
be
employed
this
reaction
presence
Rh/BINAP
complex,
resulting
corresponding
silanols
good
yields.
Additionally,
a
chiral
1,1,4,4-tetraaryl-2,3-O-isopropylidene-l-threitol-derived
phosphoramidite
ligand
used
to
yield
Si-stereogenic
silanol
with
promising
enantioselectivity.
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
88(13), С. 7953 - 7961
Опубликована: Май 26, 2023
In
this
work,
an
efficient
method
for
the
copper-catalyzed
ring-opening
hydrolysis
of
silacyclobutanes
to
silanols
was
developed.
This
strategy
has
advantages
friendly
reaction
conditions,
simple
operation,
and
good
functional
group
compatibility.
No
additional
additives
are
required
in
reaction,
S-S
bond
can
also
be
introduced
into
organosilanol
compounds
one
step.
Furthermore,
success
at
gram
scale
demonstrates
great
potential
developed
protocol
practical
industrial
applications.
European Journal of Organic Chemistry,
Год журнала:
2024,
Номер
27(23)
Опубликована: Апрель 25, 2024
Abstract
A
mini
review
focused
on
the
chemistry
of
selenosulfones
reported
since
2019
is
here
presented.
Initially,
methods
aimed
to
preparation
such
moiety
are
discussed.
Successively
1,2‐,
1,3‐,
1,4‐
and
1,7‐addition
reactions
C−C
single
multiple
bonds
illustrated.
The
forth
chapter
focuses
electrophilic
aromatic
substitutions.
fifth
deals
with
C−H
functionalizations
while
sixth
one
shows
aryl
diazonium
salts
or
its
precursors.
radical
coupling
redox
active
reagents,
subject
section
seventh.
Selenosulfones
challenged
in
nucleophilic
substitutions
phosphorus‐containing
compounds
shown
eight
nine
followed
by
conclusions
perspectives
section.
Abstract
We
have
developed
an
efficient
method
for
the
synthesis
of
2,3-dihydro-1H-1-benzosiloles
in
19%
to
90%
isolated
yield
from
1-hydrosilyl-2-ethynylbenzenes
by
using
two
equivalents
diisobutylaluminum
hydride.
The
reaction
mechanism
involves
regioselective
double
hydroalumination
alkyne
moiety
followed
cyclization
a
2-alanyldihydrobenzosilole.
A
silacyclopentane
(silolane)
was
also
synthesized
97%
corresponding
4-silylbut-1-yne
under
same
conditions.
Although
substrate-scope
study
conducted
on
0.5-mmol
scale,
gram-scale
(2-ethynylphenyl)(diphenyl)silane
optimized
conditions
successfully
afforded
desired
product
94%
without
loss
reactivity.
