Journal of Nanobiotechnology,
Год журнала:
2024,
Номер
22(1)
Опубликована: Окт. 25, 2024
Global
mortality
data
indicates
cancer
as
the
second-leading
cause
of
death
worldwide.
Therefore,
there's
a
pressing
need
to
innovate
effective
treatments
address
this
significant
medical
and
societal
challenge.
In
recent
years,
X-ray-induced
photodynamic
therapy
(X-PDT)
has
emerged
promising
advancement,
revolutionizing
traditional
(PDT)
for
deeply
entrenched
malignancies
by
harnessing
penetrating
X-rays
external
stimuli.
Recent
developments
in
X-ray
have
shown
trend
toward
minimizing
radiation
doses
remarkably
low
levels
after
proof-of-concept
demonstration.
Early
detection
real-time
monitoring
are
crucial
aspects
treatment.
Sophisticated
imaging
techniques
been
enhanced
introduction
luminescence
nano-agents,
alongside
contrast
nanomaterials
based
on
attenuation.
luminescence-based
vivo
offers
excellent
sensitivity
superior
image
quality
deep
tissues
at
reasonable
cost,
due
unhindered
penetration
unimpeded
auto-fluorescence
X-rays.
This
review
emphasizes
significance
responsive
theranostics,
exploring
their
mechanism
action,
feasibility,
biocompatibility,
prospects
imaging-guided
deep-seated
tumors.
Additionally,
it
discusses
applications
X-PDT
treating
breast
cancer,
liver
lung
skin
colorectal
cancer.
