Introduction of Methyl Group in Substituted Isoselenazolones: Catalytic and Mechanistic Study
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
88(7), С. 4273 - 4285
Опубликована: Март 17, 2023
Copper-catalyzed
direct
selenation
of
substituted
2-bromo-N-phenylbenzamide
substrates
with
elemental
selenium
powder
provided
a
series
methoxy-substituted
isoselenazolones
via
the
C-Se
and
Se-N
bond
formations.
Phenolic
have
been
obtained
by
O-demethylation
corresponding
analogues
using
boron
tribromide.
Some
structurally
characterized
X-ray
single-crystal
analysis.
The
glutathione
peroxidase
(GPx)-like
antioxidant
activity
has
evaluated
both
in
thiophenol
coupled-reductase
assays.
All
showed
good
GPx-like
activities
assay.
ferric-reducing
power
phenolic
antioxidants
also
evaluated.
best
were
found
to
be
agents.
single
electron
transfer,
hydrogen
atom
proton-coupled
transfer
mechanisms
for
properties
all
catalysts
supported
density
functional
theory
calculations.
catalytic
cycle
was
proposed
one
involving
diselenide,
selenenyl
sulfide,
selenol,
selenenic
acid
as
intermediates
77Se{1H}
NMR
spectroscopy.
Язык: Английский
Benzoimidazolyl Organoseleniums: Antioxidant Activity and Catalysts for Selective Iodination of Arenes and Nitro-Michael Reaction
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(19), С. 14328 - 14340
Опубликована: Сен. 16, 2024
Here,
the
synthesis
and
catalytic
activities
of
benzoimidazole-derived
organoselenium
compounds
have
been
explored.
The
synthesized
bis(2-benzoimidazolyl)
diselenide,
having
increased
Lewis
acidity
on
selenium
center,
outperforms
simple
phenyl
Язык: Английский
New greener approach for the Se-N bond formation
Phosphorus, sulfur, and silicon and the related elements,
Год журнала:
2023,
Номер
unknown, С. 1 - 5
Опубликована: Авг. 21, 2023
AbstractA
new
greener
protocol
that
includes
the
rapid
and
quantitative
conversion
of
diaryl
diselenides,
bearing
an
amido
function,
to
corresponding
N-substituted
benzisoselenazolones
by
254
nm
wavelength
UV
lamp
irradiation
is
presented.
This
free
radical
Se-N
bond
formation
was
utilized
for
a
series
diversified
substrates
under
mild
reaction
conditions.
Carrying
out
process
in
photochemically
inactive
solvent
like
acetonitrile
enabled
obtain
both
N-aliphatic
N-aromatic
derivatives.Keywords:
Benzisoselenazol-3(2H)-onesdiselenidesUV-lightradical
reactionbioactive
compounds
Язык: Английский