The Progress of Reductive Coupling Reaction by Iron Catalysis
The Chemical Record,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 17, 2024
Abstract
The
transition
metal
catalyzed
coupling
reaction
has
revolutionized
the
strategies
for
forging
carbon‐carbon
bonds.
In
contrast
to
traditional
cross‐coupling
methods
using
pre‐prepared
nucleophilic
organometallic
reagents,
reductive
reactions
C−C
bonds
formation
provide
some
advantages.
Because
both
partners
are
reduced
in
final
products
a
stoichiometric
amount
of
reductant,
this
approach
not
only
avoids
need
use
sensitive
species,
but
also
provides
an
orthogonal
and
complementary
access
classical
reaction.
Notably,
feature
readily
available
fragments,
promote
good
step
economy,
exhibit
high
functional
group
tolerance
unique
chemoselectivity,
which
have
propelled
their
increasingly
popular
organic
synthesis.
recent
years,
due
low
price,
minimal
toxicity,
environmentally
benign
character,
iron‐catalyzed
garnered
significant
attention
from
synthetic
chemists
pharmacologists,
especially
coupling.
This
review
aims
insightful
overview
advances
reactions,
illustrate
possible
mechanisms.
Язык: Английский
Facile Construction of Benzo[d][1,3]oxazocine: Reductive Radical Dearomatization of N-Alkyl Quinoline Quaternary Ammonium Salts
Organic Letters,
Год журнала:
2024,
Номер
26(10), С. 1996 - 2001
Опубликована: Март 4, 2024
Reductive
radical
dearomatization
N-alkyl
quinoline
quaternary
ammonium
salts
to
synthesize
structurally
complex
and
challenging
polysubstituted
benzo[d][1,3]oxazocines
was
first
reported.
The
mechanism
showed
various
allyl
alcohols
can
be
converted
into
alkyl
radicals
under
reduction
conditions
of
iron/silane.
These
then
nucleophilically
attack
the
C4
site
salts,
intramolecular
cyclization
resulting
intermediate
generates
target
product.
This
method
not
only
produced
a
series
novel
but
also
prepared
polycyclic
benzo[d][1,3]oxazocines.
Finally,
this
strategy
made
up
for
lack
reductive
reports
on
N-alkylquinolinium
had
advantages
mild
reaction
conditions,
wide
substrate
range,
product
structure.
Язык: Английский
Catalytic hydrofunctionalizations of alkenes via hydrogen atom transfer with 3d transition metal complexes (MHAT): A pragmatic approach to recent contributions
Applied Catalysis A General,
Год журнала:
2025,
Номер
unknown, С. 120379 - 120379
Опубликована: Май 1, 2025
Язык: Английский
Synthesis of polysubstituted oxazolidinones via regioselective addition of azonaphthalenes
Organic Chemistry Frontiers,
Год журнала:
2023,
Номер
10(16), С. 4086 - 4091
Опубликована: Янв. 1, 2023
A
series
of
novel
and
synthetically
challenging
oxazolidinone
compounds
were
synthesized
through
a
regioselective
radical
addition
azonaphthalenes.
Язык: Английский
Nickel-Catalyzed Three-Component Alkylarylation of Alkenyl N-Heteroarenes
Organic Letters,
Год журнала:
2023,
Номер
25(46), С. 8344 - 8349
Опубликована: Ноя. 14, 2023
A
nickel-catalyzed
three-component
alkylarylation
of
alkenyl
N-heteroarenes
with
α-bromocarboxylates
and
aryl
boronic
acids
is
reported.
The
protocol
provides
a
new
method
to
access
variety
N-heteroarene
substituted
diarylalkanes
in
moderate
good
yields.
It
features
mild
reaction
conditions,
cheap
nickel
catalyst,
readily
available
substrates,
broad
substrate
scope.
Язык: Английский
Ferrocene catalyzed carbohydroxylation of alkenes using H2O and cycloketone oxime esters
Organic & Biomolecular Chemistry,
Год журнала:
2023,
Номер
21(42), С. 8482 - 8487
Опубликована: Янв. 1, 2023
A
cyanoalkyl-hydroxylation
reaction
of
aryl
alkenes
has
been
successfully
devised,
employing
ferrocene
as
a
catalyst
for
the
addition
cycloketone
oxime
ester
and
H2O
across
double
bond
alkene.
This
environmentally
friendly
approach
employs
solvent
mixture
consisting
water
demonstrates
redox
neutrality,
along
with
exceptional
regio-
chemoselectivity,
leading
to
formation
diverse
distal
hydroxy-nitrile
compounds.
Moreover,
this
research
presents
noteworthy
contributions
in
terms
late-stage
functionalization
complex
molecules
offers
valuable
insights
into
mechanistic
aspects
reaction.
Язык: Английский
Radical Alkylation and Protonation Induced anti-Markovnikov Hydroalkylation of Unactivated Olefins via Cobalt Catalysis
Chemical Communications,
Год журнала:
2024,
Номер
60(69), С. 9258 - 9261
Опубликована: Янв. 1, 2024
A
cobalt
catalyzed
reductive
hydroalkylation
of
unactivated
olefins
with
anti-Markovnikov
selectivity
was
reported
to
access
complex
alkyl
amides.
Язык: Английский