SERS in 3D cell models: a powerful tool in cancer research
Chemical Society Reviews,
Год журнала:
2024,
Номер
53(10), С. 5118 - 5148
Опубликована: Янв. 1, 2024
3D
cancer
models
recapitulate
the
tumor
microenvironment
and
serve
as
a
platform
to
study
cell
behavior,
drug
discovery
early
diagnosis,
which
can
be
monitored
chemically
with
subcellular
resolution
in
real
time,
via
SERS.
Язык: Английский
Metallic Nanomaterials in Parkinson's Disease: A Transformative Approach for Early Detection and Targeted Therapy
Journal of Materials Chemistry B,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
This
review
article
illustrates
and
discusses
the
application
of
metallic
nanomaterials
(MNMs)
in
detection
treatment
PD,
as
well
theranostic
MNMs.
Язык: Английский
Optical biosensors for diagnosing neurodegenerative diseases
Deleted Journal,
Год журнала:
2025,
Номер
2(1)
Опубликована: Май 2, 2025
Neurodegenerative
diseases
involve
the
progressive
loss
of
neurons
in
brain
and
nervous
system,
leading
to
functional
decline.
Early
detection
is
critical
for
improving
outcomes
advancing
therapies.
Optical
biosensors,
some
which
offer
rapid,
label-free,
ultra-sensitive
detection,
have
been
applied
early
diagnosis
drug
screening.
This
review
examines
principles
performance
different
optical
biosensors
used
diagnosing
neurodegenerative
discusses
potential
future
advancements.
Язык: Английский
Advancing Brain Research through Surface-Enhanced Raman Spectroscopy (SERS): Current Applications and Future Prospects
Biosensors,
Год журнала:
2024,
Номер
14(1), С. 33 - 33
Опубликована: Янв. 10, 2024
Surface-enhanced
Raman
spectroscopy
(SERS)
has
recently
emerged
as
a
potent
analytical
technique
with
significant
potential
in
the
field
of
brain
research.
This
review
explores
applications
and
innovations
SERS
understanding
pathophysiological
basis
diagnosis
disorders.
holds
advantages
over
conventional
spectroscopy,
particularly
terms
sensitivity
stability.
The
integration
label-free
presents
promising
opportunities
for
rapid,
reliable,
non-invasive
brain-associated
diseases,
when
combined
advanced
computational
methods
such
machine
learning.
to
deepen
our
enhancing
diagnosis,
monitoring,
therapeutic
interventions.
Such
advancements
could
significantly
enhance
accuracy
clinical
further
brain-related
processes
diseases.
assesses
utility
diagnosing
disorders
Alzheimer's
Parkinson's
stroke,
cancer.
Recent
technological
advances
instrumentation
techniques
are
discussed,
including
nanoparticle
design,
substrate
materials,
imaging
technologies.
We
also
explore
prospects
emerging
trends,
offering
insights
into
new
technologies,
while
addressing
various
challenges
limitations
associated
Язык: Английский
SERS Materials with Small‐Molecule Sensitivity for Biological Diagnosis
Analysis & Sensing,
Год журнала:
2024,
Номер
4(4)
Опубликована: Янв. 31, 2024
Abstract
Small
molecule
metabolites
depict
a
biological
system‘s
status
and
help
monitor
disease
conditions.
Surface‐enhanced
Raman
scattering
(SERS)
holds
considerable
promise
as
an
instant
non‐destructive
detection
tool
for
diagnosis.
With
single‐molecular
sensitivity,
molecular
fingerprint
water
compatible,
SERS
provides
valuable
information
about
chemical
structures
analyte
compositions,
especially
desirable
in
Design
fabrication
of
effective,
stable
substrates
can
be
one
the
major
research
priorities
to
provide
small‐molecule
tracing
with
high
selectivity,
reproducibility.
Significant
efforts
have
been
directed
towards
creating
high‐performance
multifunctional
spanning
from
coinage
metals
semiconductor
materials.
However,
most
are
suffering
unsatisfied
sensitivity
small
molecules
such
volatile
organic
compounds
(VOCs)
other
biomarkers.
This
review
summarized
recent
advances
SERS‐active
their
sensing
biomarker
molecules,
VOCs
Язык: Английский
SERS detection of dopamine in artificial cerebrospinal fluid and in Parkinson’s disease-induced mouse cortex using a hybrid ZnO@Ag nanostructured platform
Microchemical Journal,
Год журнала:
2024,
Номер
206, С. 111589 - 111589
Опубликована: Сен. 8, 2024
Язык: Английский
The Role of S-Glutathionylation in Health and Disease: A Bird’s Eye View
Nutrients,
Год журнала:
2024,
Номер
16(16), С. 2753 - 2753
Опубликована: Авг. 18, 2024
Protein
glutathionylation
is
a
reversible
post-translational
modification
that
involves
the
attachment
of
glutathione
to
cysteine
residues.
It
plays
role
in
regulation
several
cellular
processes
and
protection
against
oxidative
damage.
Glutathionylation
(GS-ylation)
modulates
protein
function,
inhibits
or
enhances
enzymatic
activity,
maintains
redox
homeostasis,
shields
proteins
from
irreversible
stress.
Aberrant
GS-ylation
patterns
are
thus
implicated
various
diseases,
particularly
those
associated
with
stress
inflammation,
such
as
cardiovascular
neurodegenerative
disorders,
cancer,
many
others.
Research
recent
years
has
highlighted
potential
manipulate
for
therapeutic
purposes
strategies
imply
both
its
enhancement
inhibition
according
different
cases.
Moreover,
it
become
increasingly
evident
monitoring
status
selected
offers
diagnostic
diseases.
In
this
review,
we
try
summarize
research
field
focus
on
our
current
understanding
molecular
mechanisms
related
aberrant
GS-ylation.
Язык: Английский
SERS-based technique for accessible and rapid diagnosis of multiple myeloma in blood serum analysis
Deleted Journal,
Год журнала:
2025,
Номер
6(0), С. 1 - 1
Опубликована: Янв. 1, 2025
Язык: Английский
Graphene-Mediated Surface Enhanced Raman Spectroscopy for DNA Detection&Hybridization: Breakthroughs and Challenges
Biosensors and Bioelectronics,
Год журнала:
2025,
Номер
286, С. 117610 - 117610
Опубликована: Май 20, 2025
In
response
to
the
growing
demand
for
advanced
DNA
research,
need
refined
scientific
methodologies
has
become
increasingly
evident.
This
review
provides
a
comprehensive
synthesis
of
recent
advancements
in
application
graphene-mediated
Surface
Enhanced
Raman
Spectroscopy
(G-SERS)
detection
and
hybridization,
highlighting
its
significant
potential
biomedical
fields
particularly
gene
emphasizing
crucial
role
advancing
genetic
research.
More
importantly,
it
emphasizes
pivotal
Au
Ag
nanoparticles,
with
varying
shapes
sizes,
enhancing
signal
intensity
improving
analytical
performance,
contributions
G-SERS
both
sensitivity
selectivity
analysis.
Furthermore,
our
explores
innovative
hybrid
approaches
that
integrate
SERS
Quartz
Crystal
Microbalance
(QCM)
Atomic
Force
Microscopy
(AFM),
marking
transformative
shift
capabilities.
Overall,
this
offers
valuable
insights
into
evolving
landscape
analysis
technologies,
paving
way
future
Язык: Английский