Engineered MXene Biomaterials for Regenerative Medicine
ACS Nano,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 5, 2025
MXene-based
materials
have
attracted
significant
interest
due
to
their
distinct
physical
and
chemical
properties,
which
are
relevant
fields
such
as
energy
storage,
environmental
science,
biomedicine.
MXene
has
shown
potential
in
the
area
of
tissue
regenerative
medicine.
However,
research
on
its
applications
regeneration
is
still
early
stages,
with
a
notable
absence
comprehensive
reviews.
This
review
begins
detailed
description
intrinsic
properties
MXene,
followed
by
discussion
various
nanostructures
that
can
form,
spanning
from
0
3
dimensions.
The
focus
then
shifts
biomaterials
engineering,
particularly
immunomodulation,
wound
healing,
bone
regeneration,
nerve
regeneration.
MXene's
physicochemical
including
conductivity,
photothermal
characteristics,
antibacterial
facilitate
interactions
different
cell
types,
influencing
biological
processes.
These
highlight
modulating
cellular
functions
essential
for
Although
developing,
versatile
structural
attributes
suggest
role
advancing
Язык: Английский
MXenes as emerging materials to repair electroactive tissues and organs
Bioactive Materials,
Год журнала:
2025,
Номер
48, С. 583 - 608
Опубликована: Март 3, 2025
Язык: Английский
Future prospects of MXenes: synthesis, functionalization, properties, and application in field effect transistors
Nanoscale Advances,
Год журнала:
2023,
Номер
6(2), С. 367 - 385
Опубликована: Дек. 11, 2023
MXenes
are
a
family
of
two-dimensional
(2D)
materials
that
have
drawn
lot
interest
recently
because
their
distinctive
characteristics
and
possible
uses
in
variety
industries.
This
review
emphasizes
the
bright
future
prospects
MXene
realm
FETs.
Their
remarkable
properties,
coupled
with
tunability
compatibility,
position
as
promising
candidates
for
development
high-performance
electronic
devices.
As
research
this
field
continues
to
evolve,
potential
drive
innovation
electronics
becomes
increasingly
evident,
fostering
excitement
role
shaping
technology.
paper
presents
comprehensive
overview
materials,
focusing
on
synthesis
methods,
functionalization
strategies,
intrinsic
application
Field
Effect
Transistors
(FETs).
Язык: Английский
Unveiling cutting-edge progress in the fundamentals of MXene: Synthesis strategies, energy and bio-environmental applications
Coordination Chemistry Reviews,
Год журнала:
2024,
Номер
511, С. 215870 - 215870
Опубликована: Апрель 21, 2024
Язык: Английский
High‐Performance MXene/PEDOT‐PSS Microscale Fiber Electrodes for Neural Recording and Stimulation
Advanced Functional Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 26, 2025
Abstract
The
pursuit
of
advanced
neural
interfaces
hinges
on
developing
electrode
materials
with
enhanced
cathodic
charge
storage
capacity
(CSCc),
injection
(CIC),
and
low
impedance.
2D
nanomaterials,
particularly
MXenes,
have
emerged
as
leading
candidates
due
to
their
outstanding
electrical
properties.
However,
current
fabrication
strategies
not
fully
leveraged
the
potential
MXene,
limiting
performance
gains
in
recording
stimulation
applications.
Here,
a
novel
microscale
fiber
(MPP)
engineered
from
Ti₃C₂
MXene
PEDOT‐PSS
using
two‐step
solidification
wet
spinning
process
is
presented.
These
30
µm
fibers
exhibit
conductivity
(2.16
±
1.46)
×
10⁵
S
m
−1
,
interfacial
impedance,
high
CSCc
CIC,
achieving
substantial
improvements
signal
fidelity
efficiency.
MPP
electrodes
demonstrate
robust
electrochemical
stability,
biocompatibility,
magnetic
resonance
imaging
(MRI)
compatibility,
excelling
across
various
modalities,
including
electroencephalography
(EEG),
electromyography
(EMG),
electrocardiography
(ECG),
cortical
recordings,
subthalamic
nucleus
deep
brain
(STN‐DBS).
results
mark
significant
step
toward
scalable,
high‐performance
that
can
transform
neurotherapeutic
Язык: Английский
Application of advanced biosensors in nervous system diseases
Deleted Journal,
Год журнала:
2024,
Номер
2(4)
Опубликована: Авг. 1, 2024
Abstract
Nervous
system
diseases
are
among
the
most
common
globally,
posing
a
severe
threat
to
patients'
quality
of
life
and
placing
considerable
burden
on
families
society.
With
improvements
in
miniaturization,
intelligence,
safety
biosensors,
combination
machinery
organisms
is
becoming
increasingly
common.
In
neuroscience
research,
biosensors
different
macroscopic
dimensions
have
been
uniquely
utilized
harness
their
relevant
properties.
One‐dimensional
(1D)
can
achieve
situ
real‐time
monitoring
neural
markers
at
subcellular,
single‐cell,
ex
vivo,
vivo
levels,
with
reduced
impacts
organisms.
Two‐dimensional
(2D)
monitor
chemical
behavior
cells
activity
living
animals.
They
helpful
for
objectively
identifying
characteristics
response
external
stimuli
studying
circuits
Three‐dimensional
(3D)
shown
unique
advantages
point‐of‐care
testing,
liquid
biopsy,
drug
screening,
mechanistic
research.
clinical
practice,
brain‐computer
interfaces
(BCIs)
wearable
devices
become
important
tools
treatment.
To
date,
there
has
widespread
adoption
BCIs
practice.
not
only
exhibit
good
efficacy
neurological
mental
but
also
provide
method
early
diagnosis
treatment
these
diseases.
Wearable
sensor
accurately
assess
symptoms
movement
disorders
play
an
active
role
rehabilitation
this
review,
we
summarize
application
advanced
research
The
challenges
prospects
as
applied
nervous
under
interdisciplinary
promotion
discussed
depth.
Язык: Английский
Modulating Cell Adhesion and Infiltration in Advanced Scaffold Designs based on PLLA Fibers with rGO and MXene (Ti3C2T )
Materials Today Bio,
Год журнала:
2025,
Номер
unknown, С. 101785 - 101785
Опубликована: Апрель 1, 2025
The
development
of
electrospun
scaffolds
that
support
cell
adhesion
and
infiltration
remains
a
critical
challenge
in
tissue
engineering.
In
this
study,
we
investigate
the
influence
two-dimensional
(2D)
fillers-reduced
graphene
oxide
(rGO)
MXene
(Ti3C2T
x
)-incorporated
into
poly(L-lactic
acid)
(PLLA)
fibers
on
their
properties
osteoblast
responses.
presence
fillers
modified
fiber
arrangement
created
varying
inter-fiber
spacing
due
to
surface
charge
repulsion
agglomeration.
Importantly,
potential
measurements
via
Kelvin
probe
force
microscopy
(KPFM)
PLLA
show
significant
shift
caused
by
incorporation
Ti3C2T
∼400
mV
compared
∼50
for
rGO.
vitro
tests
indicate
rGO-modified
up
∼100
μm,
unlike
fibers,
which
limit
maximum
∼70
μm.
However,
promotes
even
deeper
(∼120
μm)
more
uniform
cell's
changes
scaffold
architecture.
High-resolution
confocal
imaging
confirmed
PLLA-Ti3C2T
fosters
larger,
elongated
site
clusters
cells,
whereas
rGO
increases
density
relation
without
any
filler.
Our
findings
highlight
distinct
roles
modulating
geometry,
mechanical
behavior,
cellular
interactions.
Tailoring
composition
distribution
conductive
offers
promising
strategy
optimizing
performance
engineering
applications.
Язык: Английский
A comprehensive and updated review on the applications of vesicular drug delivery systems in treatment of brain disorders: A shelter against storms
Journal of Drug Delivery Science and Technology,
Год журнала:
2023,
Номер
89, С. 105011 - 105011
Опубликована: Окт. 5, 2023
Язык: Английский
Unlocking the Potential of Graphene-Based Nanocomposites in Neurogenesis
Deleted Journal,
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 29, 2024
Graphene-based
nanocomposites
possess
excellent
conductivity
of
electrons,
robustness,
and
longevity,
making
them
potential
instruments
for
enhancing
neurogenesis.
Graphene
Nanocomposite
has
several
biomedical
uses
due
to
its
biocompatibility,
size,
chemical
impermeability,
antibacterial
properties,
drug
delivery.
Their
in
neuroregeneration,
methods
synthesis
are
discussed
this
overview.
Focusing
on
adult
neurogenesis
phases
such
as
proliferation,
differentiation,
migration,
integration,
study
delves
into
which
is
an
essential
process
brain
development,
plasticity,
learning.
The
made
graphene
have
applications,
including
stimulating
treating
neurological
diseases.
To
maximize
their
use
neuroregeneration
medication
delivery
systems,
future
studies
should
find
ways
address
problems
with
toxicity
functionalization.
This
review
emphasizes
the
intriguing
prospects
application
Neuronal
evolution
accurate
systems
two
arenas
where
experts
endeavor
enhance
compatibility
strength.
Язык: Английский