Chemical Communications, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

A one-pot Nazarov cyclization/oxidative 1,2-carbon rearrangement/Ritter reaction has been explored for the first time, facilitating synthesis of unprecedented 2,3-disubstituted-5-quaternary-4-amidocyclopent-2-enone and 2-quaternary-3-amidoindanones. This transformation features convenient operation, good yields (up to 70%), excellent diastereoselectivity 20 : 1). The proposed mechanism is supported by some experimental results.

Язык: Английский