Cyanation with isocyanides: recent advances and perspectives
Chemical Communications,
Год журнала:
2024,
Номер
60(12), С. 1546 - 1562
Опубликована: Янв. 1, 2024
This
review
focuses
on
the
cyanation
of
isocyanides
with
recent
advances
and
perspectives.
Язык: Английский
C–H functionalization enabled by multiple isocyanides
Chemical Society Reviews,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
This
review
outlines
in
detail
strategies
for
state-of-the-art
synthetic
routes
and
demonstrates
various
interactions
from
the
synergistic
combination
of
C–H
functionalization
with
multiple
isocyanides
to
establish
complicated
reactions.
Язык: Английский
Oxalic acid as a dual C1 surrogate for heterogeneous palladium-catalyzed tandem four-component quinazolinone synthesis
Chemical Communications,
Год журнала:
2024,
Номер
60(47), С. 6043 - 6046
Опубликована: Янв. 1, 2024
Herein,
a
heterogeneous
Pd/C-catalyzed
direct
one-step
four-component
double
carbonylative
approach
for
cascade
synthesis
of
2-aryl
quinazolinones
has
been
reported
the
first
time
starting
from
2-iodoaniline
derivatives
and
aryl
iodides.
The
given
reaction
involves
simultaneous
implementation
two
different
gaseous
surrogates
Язык: Английский
[1,2]‐Phospha‐Brook Rearrangement‐Initiated Palladium‐Catalyzed Cyclization Reaction of Isocyanides and o‐Bromobenzaldehydes: Access to 2H‐Isoindole‐1‐carboxamides and 2H‐Isoindole‐1‐carbonitriles
Chinese Journal of Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 20, 2024
Comprehensive
Summary
Herein,
a
[1,2]‐phospha‐Brook
rearrangement‐initiated
palladium‐catalyzed
cyclization
reaction
for
base‐controlled
selective
synthesis
of
2
H
‐isoindole‐1‐carboxamide
and
‐isoindole‐1‐carbonitrile
derivatives
has
been
described.
This
strategy
features
double
isocyanide
insertion,
efficient
bond
combinations,
simple
operation
conditions.
Mechanistic
studies
show
that
the
rearrangement
is
key
step
in
this
reaction.
protocol
offers
novel
concise
‐isoindole
derivatives.
Язык: Английский
Rapid Access to Fused Tetracyclic N-Heterocycles via Amino-to-Alkyl 1,5-Palladium Migration Coupled with Intramolecular C(sp3)–C(sp2) Coupling
Organic Letters,
Год журнала:
2023,
Номер
25(34), С. 6272 - 6277
Опубликована: Авг. 21, 2023
An
unprecedented
route
for
the
preparation
of
fused
tetracyclic
N-heterocycles
is
presented
through
palladium-catalyzed
cyclization
isocyanides
with
alkyne-tethered
aryl
iodides.
In
this
transformation,
a
novel
amino-to-alkyl
1,5-palladium
migration/intramolecular
C(sp3)-C(sp2)
coupling
sequence
was
observed
first.
More
importantly,
isocyanide
exhibited
three
roles,
serving
simultaneously
as
C1
synthon,
C1N1
and
donor
C(sp3)
coupling,
reaction
sole
successful
example
that
achieved
C(sp3)-H
activation
isocyanide.
Язык: Английский