Abstract
In
response
to
the
growing
concerns
about
unauthorized
use
of
advanced
secondary
explosives
such
as
TKX‐50
against
non‐combatant
targets,
there
is
an
urgent
need
for
effective
detection
methods
or
techniques
ensure
efficient
security
screening,
homeland
security,
and
public
safety.
Herein,
a
new
polymeric
receptor
(IV)
derived
from
functionalized
tetraphenylethylene
moiety
(TPE)
1,3,5‐tris(4‐aminophenyl)benzene
(TAPB)
moieties
through
‘switch
ON’
luminescence
upon
specific
binding
explosive,
reported.
The
observed
‘luminescence
rationalized
based
on
charge
transfer
complex
formation
between
IV
(
K
=
1.7
×
10
4
m
−1
).
This
validated
by
steady
excited‐state
studies,
along
with
detailed
computational
studies.
authors’
presumptions
are
further
adequate
control
studies
using
appropriate
monomeric
derivative
(III)
TPE.
Moreover,
this
can
be
integrated
into
smart
user‐friendly
Internet
Things
(IoT)‐based
prototype
device.
device
effectively
convert
optical
responses
digital
output
develop
real‐time
in
solution.
lightweight,
portable
ideally
suited
remote
surveillance
monitoring
TKX‐50;
examples
rare
contemporary
literature.
Critical Reviews in Analytical Chemistry,
Год журнала:
2025,
Номер
unknown, С. 1 - 21
Опубликована: Фев. 19, 2025
Manganese
is
an
essential
metal
ion
involved
in
various
biological
and
environmental
processes,
but
its
excess
can
lead
to
toxicity,
particularly
affecting
the
nervous
system.
Therefore,
developing
selective
sensitive
detection
methods
for
Mn2+
ions
of
paramount
importance.
Colorimetric
fluorimetric
chemosensors
have
emerged
as
promising
tools
due
their
simplicity,
cost-effectiveness,
real-time
monitoring
capabilities.
This
review
discusses
recent
advances
colorimetric
that
exhibit
distinct
color
or
fluorescence
changes
upon
interaction
with
ions.
The
explores
different
organic
nanomaterials,
focusing
on
mechanisms
sensing,
sensitivity,
selectivity,
practical
applications
monitoring,
healthcare,
food
safety.
article
also
provides
insights
into
future
research
directions
aimed
at
overcoming
these
challenges,
improving
chemosensor
performance,
expanding
applicability
diverse
real-world
scenarios.
Abstract
The
intriguing
effect
of
metal
ions
and
biomolecules
on
various
biological
entities
warrants
developing
selective
sensitive
fluorescent
chemosensors
in
water
other
organic
solvents.
A
review
comparable
literature
related
areas,
including
material
chemistry,
environmental
science,
supramolecular
indicates
that
most
the
research
work
is
carried
out
varying
types
existing
chemosensor
explores
use
solvents,
DMSO/H₂O,
methanol,
DMF/HEPES
systems,
photoinduced
electron
transfer
(PET)‐based
chemosensors.
DMSO
DMF
are
strong
polar
solvents
resulting
fluorescence
emission.
Additionally,
dichlorobenzene
chlorobenzene
employed
to
form
gels
with
urea
compounds,
further
improving
sensor's
functionality
selectivity.
Also,
parallel
investigations,
when
as
a
solvent,
revealed
decrease
binding/
detection
ability
guest
analytes
since
molecules
strongly
solvated
(hydrated)
moieties,
whereas
non‐polar
(or
amphiphilic
molecules)
found
aggregations
or
self‐assemblies.
present
attempts
analyze
characterize
water‐soluble
(FCHs)
into
cyclic
acyclic
per
their
topological
structural
architectures.
In
addition,
seminal
examples
synthetic
FCHs,
included
herein,
provide
an
understanding
rational
designs,
fundamental
properties,
interactions,
emerging
switchable
properties
aqueous
medium.
Thus,
knowledge
these
high
affinity
selectivity
would
facilitate
synthesis
novel
FCHs
potential
future
applications.
Critical Reviews in Analytical Chemistry,
Год журнала:
2025,
Номер
unknown, С. 1 - 27
Опубликована: Янв. 21, 2025
Organic
fluorescence
and
colorimetric
probes
have
emerged
as
vital
tools
for
detecting
metal
ions,
due
to
their
high
sensitivity,
selectivity,
rapid
response
times.
Copper,
an
essential
trace
element,
plays
a
critical
role
in
biological
systems,
yet
its
imbalance
can
lead
severe
disorders
such
neurodegenerative
diseases,
cancer,
Wilson's
disease.
Over
the
past
few
years,
advancements
probe
design
unlocked
innovative
avenues
not
only
Cu2+
environmental
samples
but
also
visualizing
distribution
through
imaging.
These
offering
robust
performance
under
diverse
conditions.
Fluorescence
imaging
using
these
pivotal
cancer
diagnosis,
prognosis,
treatment
monitoring
by
real-time
visualization
of
tumor
morphology
biomolecular
interactions
at
cellular
tissue
levels.
This
review
aims
explore
diversity
organic
developed
detection
Cu2+,
with
particular
focus
on
applications
from
2020
2024.
The
discussion
highlights
use
various
cells
SiHa,
HCT
116,
GES-1,
RAW
264.7,
HepG2,
HeLa,
MCF-7
DrG
cell
lines,
tissues,
small
living
organisms.
By
targeting
cancer-specific
pathways
copper-related
physiological
changes,
significantly
advanced
fields
diagnostics
therapeutics.
comprehensive
analysis
emphasizes
potential
powerful
tool
elucidating
roles
health
disease,
paving
way
future
advances
biomedical
research.
The
presence
of
Hg
2+
causes
substantial
stress
to
plants,
adversely
affecting
growth
and
health
by
disrupting
cell
cycle
divisions,
photosynthesis,
ionic
homeostasis.
Accurate
visualization
the
spatiotemporal
distribution
in
plant
tissues
is
crucial
for
management
pollution;
however,
related
research
still
at
its
early
stage.
Herein,
a
small-molecule
amphiphilic
fluorescent
probe
(termed
LJTP2
)
was
developed
specific
detection
with
high
sensitivity
(~16
nM).
Fluorescent
imaging
applications
not
only
detected
dynamic
within
cells
subcellular
level
but
also
enabled
understanding
membrane
under
stress.
This
study
introduces
valuable
tool
elucidating
molecular
mechanism
demonstrating
potential
application
probes
science.
Chemosensors,
Год журнала:
2025,
Номер
13(3), С. 113 - 113
Опубликована: Март 20, 2025
Cost-effective
chemosensors
have
become
an
indispensable
tool
for
sustainable
monitoring
in
food
safety
and
processing,
where
there
is
urgent
need
affordable,
efficient,
real-time
analytical
solutions.
This
review
discusses
recent
advances
low-cost
chemosensor
technologies,
highlighting
developments
materials,
miniaturization,
integration
into
portable
accessible
platforms.
The
focus
on
applications
detecting
contaminants,
quality,
ensuring
production
processing.
also
addresses
the
challenges
related
to
sensor
sensitivity,
selectivity,
operational
stability
provides
insights
future
directions
role
of
supporting
practices
these
important
sectors.
