Protective effect of thymoquinone against doxorubicin-induced cardiotoxicity and the underlying mechanism DOI
Yi Chen,

Wei Luo,

Yanqing Wu

и другие.

Toxicology and Applied Pharmacology, Год журнала: 2024, Номер 495, С. 117179 - 117179

Опубликована: Дек. 5, 2024

Язык: Английский

Chemiluminescent transition metal complexes: Mechanisms and applications DOI
Jinghui Zhu,

Mingrui Gu,

Yahui Chen

и другие.

Coordination Chemistry Reviews, Год журнала: 2025, Номер 530, С. 216495 - 216495

Опубликована: Фев. 5, 2025

Язык: Английский

Процитировано

1
Luciferase complementation for cellular assays beyond protein–protein interactions DOI Open Access
Genki Kawamura,

Takeaki Ozawa

Analytical Sciences, Год журнала: 2025, Номер unknown

Опубликована: Фев. 18, 2025

Abstract Luciferase complementation assays have emerged in 2001 as a useful tool to analyze biological processes through diverse such cellular studies and vivo imaging. The assay has an advantage of wide dynamic ranges, high signal-to-noise ratios, capability for real-time monitoring events with readout bioluminescence. While it was initially harnessed detecting protein–protein interactions, biosensors based on luciferase-fragment achieved significant advancements their designs, expanding versatility applicability beyond the initial scope. This review aims provide comprehensive overview designing strategies employed split luciferase highlight bioanalytical applications. Because simple bi-molecular detection interactions by this approach is well-established, will focus introducing sensor designs using concept complementation. Graphical abstract

Язык: Английский

Процитировано

0
In vivo monitoring of endogenous hydrogen sulfide and evaluation of natural protectants in liver injury mice using a highly selective bioluminescent probe DOI
Chong Hu,

Zeping Yang,

Xiaorui Shi

и другие.

Biosensors and Bioelectronics, Год журнала: 2025, Номер 278, С. 117343 - 117343

Опубликована: Март 5, 2025

Язык: Английский

Процитировано

0
Exploring the Synergy Between Bioluminescence and Nanomaterials: Innovations in Analytical and Therapeutic Applications DOI
Polina M. Ivantcova,

Adilya R Sungatullina,

Kristina V Pidgirnaya

и другие.

Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер unknown, С. 114631 - 114631

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Functional Materials Targeted Regulation of Gasdermins: From Fundamentals to Functionalities and Applications DOI Creative Commons
Luyao Tian, Shilong Piao, Xia Li

и другие.

Advanced Science, Год журнала: 2025, Номер unknown

Опубликована: Март 24, 2025

Abstract Targeted regulation of pyroptosis to modulate the immune landscape has emerged as a novel design strategy for cancer immunotherapy and anti‐inflammatory therapy. However, acts double‐edged sword, making it important optimize strategies functional materials appropriately activate effective disease treatment. This paper summarizes discusses structure, pore formation, molecular mechanisms “executor” Gasdermins, well events preceding following these processes. Subsequently, focus is on reviewing that directly regulate Gasdermin formation target those indirectly before after control activity. Finally, advantages, disadvantages, future prospects designing such are provided, aiming facilitate precise design, pharmacological investigation, clinical translation pyroptosis‐related materials.

Язык: Английский

Процитировано

0
Protective effect of thymoquinone against doxorubicin-induced cardiotoxicity and the underlying mechanism DOI
Yi Chen,

Wei Luo,

Yanqing Wu

и другие.

Toxicology and Applied Pharmacology, Год журнала: 2024, Номер 495, С. 117179 - 117179

Опубликована: Дек. 5, 2024

Язык: Английский

Процитировано

2