Journal of Materials Chemistry C,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 4, 2024
We
developed
a
hydrogel
controlled
by
near-infrared
light.
The
NIR
light
excites
nanoparticles
to
produce
upconversion
luminescence
and
polymerizes
gelatin
monomers
into
the
long-chain
compound
GelMa
in
presence
of
photoinitiator
LAP.
Polymers for Advanced Technologies,
Год журнала:
2025,
Номер
36(4)
Опубликована: Апрель 1, 2025
ABSTRACT
Smart
polymeric
micelles
have
emerged
as
versatile
nanocarriers
in
targeted
drug
delivery,
driven
by
their
unique
ability
to
encapsulate
therapeutic
agents
and
deliver
them
with
precision
specific
sites.
This
review
delves
into
the
recent
advancements
design,
functionality,
biomedical
applications
of
these
nanostructures,
emphasizing
role
enhancing
efficacy
while
minimizing
systemic
toxicity.
The
begins
discussing
principles
behind
stimuli‐responsive
micelles,
exploring
mechanisms
triggered
pH,
redox
conditions,
temperature,
light
achieve
controlled
release.
It
highlights
advances
functionalization
strategies,
including
surface
modifications
targeting
ligands
stimuli‐sensitive
linkages,
which
enhance
specificity
adaptability
pathological
microenvironments.
Subsequent
sections
focus
on
cutting‐edge
applications,
particularly
cancer
therapy,
regenerative
medicine,
theranostics,
showcasing
potential
addressing
complex
clinical
challenges.
Emerging
technologies,
such
multi‐stimuli‐responsive
systems
hybrid
are
explored
for
overcome
limitations
loading,
stability,
release
profiles.
Despite
significant
progress,
current
technologies
still
face
challenges,
achieving
consistent
reproducible
loading
efficiencies,
maintaining
stability
physiological
environments,
controlling
precise
kinetics,
ensuring
scalable
cost‐effective
production
methods.
concludes
a
discussion
challenges
future
perspectives
field,
need
integrating
advanced
polymer
chemistry,
nanotechnology,
biomedicine
develop
next‐generation
smart
micelles.
By
providing
comprehensive
overview,
this
article
aims
underscore
transformative
advancing
medicine
interventions.
Journal of Population Therapeutics and Clinical Pharmacology,
Год журнала:
2024,
Номер
unknown, С. 2080 - 2092
Опубликована: Фев. 22, 2024
Introduction:
Chronic
wound
treatment
poses
a
significant
challenge,
consuming
substantial
time
and
resources
for
medical
nursing
staff.
A
multitude
of
materials
are
available
assistance,
necessitating
careful
selection
process
to
optimize
efficacy
streamline
treatments.
The
cornerstone
this
is
comprehensive
assessment
both
the
patient's
overall
condition
specific
characteristics.
Background:
market
offers
diverse
array
designed
aid
in
chronic
care.
However,
these
contingent
upon
judicious
guided
by
thorough
understanding
health
status
unique
attributes
wound.
This
underscores
importance
systematic
approach
material
selection.
Objective:
primary
objective
bulletin
provide
guidance
healthcare
professionals
strategic
By
offering
insights
into
patient
assessment,
aims
enhance
effectiveness
strategies.
Methods:
emphasizes
methodical
approach,
encouraging
practitioners
invest
synthesizing
information
from
assessments,
can
make
informed
decisions
selecting
Results:
outcomes
meticulous
serve
as
foundation
optimal
employing
efficiency
treatments
and,
consequently,
contribute
improved
outcomes.
Discussion:
discussion
section
delves
significance
It
highlights
impact
an
decision-making
on
efficacy,
emphasizing
holistic
caring
wounds.
Conclusion:
In
conclusion,
serves
valuable
resource
staff
engaged
advocating
based
it
empower
utilization
Journal of Materials Chemistry C,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 4, 2024
We
developed
a
hydrogel
controlled
by
near-infrared
light.
The
NIR
light
excites
nanoparticles
to
produce
upconversion
luminescence
and
polymerizes
gelatin
monomers
into
the
long-chain
compound
GelMa
in
presence
of
photoinitiator
LAP.