Doughnut-shaped bimetallic Cu–Zn-MOF with peroxidase-like activity for colorimetric detection of glucose and antibacterial applications

Talanta, Год журнала: 2024, Номер 279, С. 126544 - 126544

Опубликована: Июль 14, 2024

Язык: Английский

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Enhanced Peroxidase-Like Activity of Au@Pt-TiO2 Nanocomposite under Ultrasound Stimulus for Efficient ROS Generation in Medical Applications

Journal of Inorganic and Organometallic Polymers and Materials, Год журнала: 2025, Номер unknown

Опубликована: Янв. 7, 2025

Язык: Английский

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Toward the Integration of Machine Learning and Molecular Modeling for Designing Drug Delivery Nanocarriers

Advanced Materials, Год журнала: 2024, Номер unknown

Опубликована: Сен. 10, 2024

Abstract The pioneering work on liposomes in the 1960s and subsequent research controlled drug release systems significantly advances development of nanocarriers (NCs) for delivery. This field is evolved to include a diverse array such as liposomes, polymeric nanoparticles, dendrimers, more, each tailored specific therapeutic applications. Despite significant achievements, clinical translation limited, primarily due low efficiency delivery an incomplete understanding nanocarrier interactions with biological systems. Addressing these challenges requires interdisciplinary collaboration deep nano‐bio interface. To enhance design, scientists employ both physics‐based data‐driven models. Physics‐based models provide detailed insights into chemical reactions at atomic molecular scales, while leverage machine learning analyze large datasets uncover hidden mechanisms. integration presents harmonizing different modeling approaches ensuring model validation generalization across However, this crucial developing effective targeted By integrating enhanced data infrastructure, explainable AI, computational advances, potentials, researchers can develop innovative nanomedicine solutions, ultimately improving outcomes.

Язык: Английский

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Construction of antimicrobial CeO2/Fe2O3 nanomaterials with enzyme-like activity and study of their mechanisms

Separation and Purification Technology, Год журнала: 2024, Номер 353, С. 128448 - 128448

Опубликована: Июнь 15, 2024

Язык: Английский

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Enzyme-Like Activity Artificial Metalloenzymes

Topics in organometallic chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

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Bol-miR168a is a key regulator of defense responses to Sclerotinia sclerotiorum in Brassica oleracea

Plant Cell Reports, Год журнала: 2025, Номер 44(3)

Опубликована: Фев. 27, 2025

Язык: Английский

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Ultrasound-responsive Smart Biomaterials for Bone Tissue Engineering

Journal of Materials Chemistry B, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Bone defects resulting from trauma, tumors, or other injuries significantly impact human health and quality of life. However, current treatments for bone are constrained by donor shortages immune rejection. tissue engineering has partially alleviated the limitations traditional repair methods. The development smart biomaterials that can respond to external stimuli modulate biofunctions become a prominent area research. Ultrasound technology is regarded as an optimal "remote controller" "trigger" biomaterials. This review reports comprehensive systematic overview ultrasound-responsive It presents fundamental theories repair, definition ultrasound, its applications. Furthermore, summarizes ultrasound effect mechanisms their roles in including detailed studies on anti-inflammation, immunomodulation, cell therapy. Finally, advantages future prospects this field discussed.

Язык: Английский

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Group IB Metal‐Based Nanomaterials for Antibacterial Applications

Small Science, Год журнала: 2025, Номер unknown

Опубликована: Март 9, 2025

Pathogenic bacteria pose significant threats to human health. In recent years, escalating bacterial resistance against antibiotics has diminished their efficacy in treating infections like pneumonia, tuberculosis, and sepsis, making some cases virtually untreatable. Hence, there is an urgent demand for novel approaches combat threats. Group IB metal‐based nanomaterials including copper, silver, gold have attracted considerable attention the field of antibacterial research owing remarkable broad‐spectrum bactericidal properties. Their high efficacy, ease synthesis, amenability functionalization render group highly promising diverse applications domain. This review comprehensively elucidates on mechanisms IB‐group addressing infections. Additionally, insights into challenges associated with utilizing such purposes while outlining future directions are provided.

Язык: Английский

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Metal-Free Antioxidant Nanozyme Incorporating Bioactive Hydrogel as an Antioxidant Scaffold for Accelerating Bone Reconstruction

Biomaterials, Год журнала: 2025, Номер unknown, С. 123285 - 123285

Опубликована: Март 1, 2025

Язык: Английский

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Aptamer-controlled gold nanozyme sensor for fluorescent and colorimetric dual-channel detection of methamphetamine

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Год журнала: 2024, Номер 323, С. 124883 - 124883

Опубликована: Июль 25, 2024

Язык: Английский

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