Science China Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 13, 2024
Abstract
Photodynamic
therapy
(PDT)
is
a
promising
cancer
treatment
that
uses
photosensitizers
(PSs)
to
generate
cytotoxic
reactive
oxygen
species
(ROS)
under
light,
but
improving
its
efficacy
crucial
for
clinical
applications.
To
address
this,
we
propose
smart
nanoplatform
(P@BAO-DOX)
synergistic
chemo-photodynamic
therapy,
featuring
efficient
PDT,
controllable
drug
release,
and
fluorescence
imaging
guidance.
We
designed
an
aggregation-induced
emission
(AIE)-based
PS
(BAO)
with
effective
ROS
generation
NIR-II
fluorescence.
Additionally,
BAO
as
doxorubicin
(DOX)
chemo
were
encapsulated
in
pH-responsive
nanogels
(PNA)
obtain
P@BAO-DOX
nanogels.
Upon
uptake
by
tumor
cells,
the
nanogel
releases
drugs
acidic
conditions,
leading
cell
death.
White
light
irradiation
further
triggers
produce
substantial
ROS,
enhancing
phototoxicity
chemo-PDT
therapy.
Thus,
nanogels,
nanoplatform,
offer
precise
release
imaging-guided
showing
promise
advancing
treatment.
MXenes,
a
novel
class
of
two-dimensional
(2D)
materials,
have
attracted
considerable
attention
in
various
fields,
especially
drug
delivery,
wound
healing,
bone
tissue
engineering,
biosensing,
and
cancer
treatment.
Thanks
to
their
remarkable
physicochemical
properties,
MXenes
hold
great
promise
for
biomedical
applications.
Concurrently,
hydrogels
composed
polymers
been
extensively
utilized
contexts.
The
unique
properties
facilitate
integration
into
bioactive
with
enhanced
functions
thereby
endowing
the
composites
multifunctional
capabilities.
MXene-reinforced
polymer
(MRPHs)
synergistically
combine
advantageous
characteristics
both
hydrogels,
making
them
highly
adaptable
other
theranostic
strategies
medical
In
this
comprehensive
review,
we
demonstrate
recent
advances
design
synthesis
MRPHs
Specifically,
introduce
analyze
methods
tailoring
by
incorporating
active
components,
including
functional
molecules,
2D
metal
ions,
natural
polymers,
drugs/genes.
We
then
discuss
applications
designed
biosensors,
therapy.
hope
that
work
provides
valuable
guidance
inspiration
readers
develop
advanced
Energy & Fuels,
Год журнала:
2024,
Номер
38(22), С. 22554 - 22573
Опубликована: Окт. 31, 2024
Recently,
metal–organic
framework
(MOF)-derived
binary
transition-metal
oxide
(BTMO)
holds
promise
as
an
ideal
electrode
material
for
energy-storage
applications.
Here,
we
report
a
facile
synthesis
procedure
of
MOF-derived
BTMO
that
commences
with
the
preparation
Cu-MOF
through
coordination
Cu2+
2-MeIM.
Subsequently,
Ni2+
is
introduced
into
to
create
and
clusters,
resulting
in
formation
Ni-Cu-MOF.
Finally,
annealing
Ni-Cu-MOF
led
nanoflakes
morphology
Ni2CuO3/CuO
(denoted
NCO/CuO)
composite
serves
efficient
pathway
both
ion
electron
transportation,
creating
plentiful
active
sites
faradaic
charge
storage
process.
Impressively,
NCO/CuO
demonstrates
significantly
higher
specific
capacity
(Cs)
613.54
C/g
compared
(301.11
C/g)
at
current
density
1
A/g
retains
66.3%
its
initial
capacitance
15
A/g.
Similarly,
Fe2O3-doped
nitrogen-doped
reduced
graphene
Fe2O3/N-rGO)
prepared
hydrothermal
method
(Csp)
603.39
F/g
A/g,
surpassing
counterparts,
Fe2O3,
N-rGO
39.6%
even
flexible
asymmetric
supercapacitor
(ASC)
device
was
designed
assembled
using
positive
electrode,
Fe2O3/N-rGO
negative
PVA-KOH
gel
electrolyte.
The
Ni2CuO3/CuO//Fe2O3/N-rGO
ASC
excellent
energy
48.26
Wh/kg
maximum
power
11
250
W/kg
86%
after
10
000
cycles
These
findings
provide
valuable
insights
high-performance
devices
next-generation
portable
electronics.
ACS Applied Materials & Interfaces,
Год журнала:
2024,
Номер
16(25), С. 32118 - 32127
Опубликована: Июнь 11, 2024
The
SARS-CoV-2
(COVID-19)
pandemic
outbreak
led
to
enormous
social
and
economic
repercussions
worldwide,
felt
even
this
date,
making
the
design
of
new
therapies
combat
fast-spreading
viruses
an
imperative
task.
In
face
this,
diverse
cutting-edge
nanotechnologies
have
risen
as
promising
tools
treat
infectious
diseases
such
COVID-19,
well
challenging
illnesses
cancer
diabetes.
Aside
from
these
applications,
nanoscale
metal-organic
frameworks
(nanoMOFs)
attracted
much
attention
novel
efficient
drug
delivery
systems
for
pathologies.
However,
their
potential
anti-COVID-19
therapeutic
agents
has
not
been
investigated.
Herein,
we
propose
a
pioneering
anti-COVID
MOF
approach
by
studying
safe
intrinsically
antiviral
through
screening
various
nanoMOF.
iron(III)-trimesate
MIL-100
showed
noteworthy
effect
against
at
micromolar
range,
ensuring
high
biocompatibility
profile
(90%
viability)
in
real
infected
human
cellular
scenario.
This
research
effectively
paves
way
toward
based
on
nanoMOFs,
only
but
also
other
and/or
pulmonary
diseases.
Advanced Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 5, 2025
Abstract
Multiple
stimuli‐responsive
materials
hold
excellent
potential
for
the
next
generation
smart
owing
to
their
unique
response
external
stimuli,
providing
a
powerful
impetus
development
of
intelligent
optical
devices.
The
behavior
common
multiple
are
independent
each
other,
causing
lack
multiplicity
and
identification
information
technology,
which
is
easy
decode.
Herein,
QIPA‐Eu‐1
QIPA‐Eu‐2
isomers
were
prepared
from
QIPA
EuCl
3
·6H
2
O
in
different
solvent
thermal
conditions
building
sequential
stimuli‐response
(SSR)
system.
Solvent‐driven
structural
transformations
into
QIPA‐Eu‐3
occurred,
along
with
color
change
fluorescence
emission
variation
ascribed
aggregates.
Furthermore,
displayed
photochromic
behaviors.
Combining
theoretical
calculation
well‐defined
experiments
reveal
mechanism,
it
was
found
that
light
drove
dihedral
angles
between
quinoline
nucleus
adjacent
benzene
rings
Finally,
on
basis
stimuli‐induced
stepwise
responsive
QIPA‐Eu‐1,
logic
gate
time‐dependent
dynamic
anti‐counterfeiting
pattern
successfully
constructed.
This
study
provided
new
perspective
design
construction
SSR
system,
showed
promising
fields
data
transmission
encryption.
