Palladium‐Catalyzed 2‐Aminoacetophenone Oxime Directed β‐sp2 and γ‐sp3 C─H Bond Functionalization of Aryl Carboxamides DOI
Rathinam Sankar, Gnanasambandam Vasuki

ChemistrySelect, Год журнала: 2024, Номер 9(45)

Опубликована: Ноя. 26, 2024

Abstract Pd(II)‐catalyzed 2‐aminoacetophenone oxime‐assisted sp 2 and 3 C─H arylation of aryl carboxamides is disclosed. The oxime an N,N ‐bidentate auxiliary that proceeds activation through a six‐membered palladacycle intermediate, the activation/functionalization on C(sp )─H bond by ligand novel achieved. This facilitates subsequent in one step. optimized protocol enables access to various groups at β ‐sp ‐ γ ‐centers carboxamides. bidentate easy synthesize gram scale, we also described deoximination procedure after functionalization.

Язык: Английский

Visible-Light-Catalyzed Fast Synthesis of 1,4-Benzoxazepine Derivatives from 2-Alkoxyarylaldehydes and N-Arylglycines DOI
Sheng Huang, Haibo Zhu, Anbang Wang

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 3, 2025

A novel photocatalytic method for the synthesis of 1,4-benzoxazepine using 2-alkoxyarylaldehyde as an oxygen source and N-arylglycine a nitrogen has been reported. This is mild, efficient, fast, corresponding reaction can be completed within 2 h at room temperature under atmosphere light-irradiation conditions. Mechanistic studies have confirmed that this scheme involves decarboxylation cyclization provides convenient pathway preparation various 2-alkyl-N-phenyl-substituted 1,4-benzoxazepine.

Язык: Английский

Процитировано

1
Visible light-mediated synthesis of quinazolinones from benzyl bromides and 2-aminobenzamides without using any photocatalyst or additive DOI
Sheng Huang, Liang Jin, Yufeng Liu

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2023, Номер 22(4), С. 784 - 789

Опубликована: Дек. 20, 2023

The synthesis of quinazolinones via a visible light-mediated reaction benzyl bromides with 2-aminobenzamides is reported, and the HBr generated during first step promoted subsequent step.

Язык: Английский

Процитировано

9
Visible-light induced cascade sulfonation/cyclization reaction in water towards sulfonated dihydroisoquinolino[1,2-b]quinazolinone DOI
Jun Huang, J. J. Qin,

Caijin Ban

и другие.

Chinese Chemical Letters, Год журнала: 2025, Номер unknown, С. 111379 - 111379

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0
Copper and electrocatalytic synergy for the construction of fused quinazolinones with 2-aminobenzaldehydes and cyclic amines DOI Creative Commons
Yujie Shi, Ganpeng Li,

Ruirui Wang

и другие.

RSC Advances, Год журнала: 2024, Номер 14(44), С. 32195 - 32199

Опубликована: Янв. 1, 2024

A new copper and electrocatalytic synergy strategy for efficiently constructing fused quinazolinones has been developed.

Язык: Английский

Процитировано

0
Palladium‐Catalyzed 2‐Aminoacetophenone Oxime Directed β‐sp2 and γ‐sp3 C─H Bond Functionalization of Aryl Carboxamides DOI
Rathinam Sankar, Gnanasambandam Vasuki

ChemistrySelect, Год журнала: 2024, Номер 9(45)

Опубликована: Ноя. 26, 2024

Abstract Pd(II)‐catalyzed 2‐aminoacetophenone oxime‐assisted sp 2 and 3 C─H arylation of aryl carboxamides is disclosed. The oxime an N,N ‐bidentate auxiliary that proceeds activation through a six‐membered palladacycle intermediate, the activation/functionalization on C(sp )─H bond by ligand novel achieved. This facilitates subsequent in one step. optimized protocol enables access to various groups at β ‐sp ‐ γ ‐centers carboxamides. bidentate easy synthesize gram scale, we also described deoximination procedure after functionalization.

Язык: Английский

Процитировано

0